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2.7.7.14: ethanolamine-phosphate cytidylyltransferase

This is an abbreviated version!
For detailed information about ethanolamine-phosphate cytidylyltransferase, go to the full flat file.

Word Map on EC 2.7.7.14

Reaction

CTP
+
Ethanolamine phosphate
=
diphosphate
+
CDP-ethanolamine

Synonyms

CTP-phosphoethanolamine cytidylyltransferase, CTP:ethanolaminephosphate cytidylyltransferase, CTP:phosphoethanolamine CT, CTP:phosphoethanolamine cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase gene, cytidylyltransferase, ethanolamine phosphate, ECT, ET, ethanolamine phosphate cytidylyltransferase, ethanolamine-phosphate cytidylyltransferase, Pcyt2, Pcyt2alpha, Pcyt2beta, PECT1, phosphoethanolamine cytidyltransferase, phosphoethanolamine cytidylyltransferase, phosphorylethanolamine transferase, Tb11.01.5730

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.14 ethanolamine-phosphate cytidylyltransferase

Cloned

Cloned on EC 2.7.7.14 - ethanolamine-phosphate cytidylyltransferase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
cDNA encoding CTP:phosphoethanolamine cytidylyltransferase is transiently or stably transfected in CHO cells and a rat liver-derived cell line (McA-RH7777), resulting in a maximum of 26fold and 4fold increase in specific activity of CTP:phosphoethanolamine cytidylyltransferase respectively
-
expressed in COS-7 cells
expression in Escherichia coli as a fusion protein with maltose-binding protein
His-tagged version expressed in Escherichia coli BL21(DE3)
Pcyt2, DNA and amino acid sequence and promoter determination and analysis, three splicing isoforms of Pcyt2, alpha, beta, and gamma, encoded by a single Pcyt2 gene, genetic structures. Transcriptional regulation of Pcyt2, overview
-
Pcyt2, two splicing isozymes Pcyt2alpha and Pcyt2beta, DNA and amino acid sequence and promoter determination and analysis, human Pcyt2, cDNA isolated from glioblastoma cells, is able to restore the synthesis of CDP-ethanolamine as well as the formation of PE in the enzyme-deficient yeast mutant. Transcriptional regulation of Pcyt2, overview
-
Pcyt2, two splicing isozymes Pcyt2alpha and Pcyt2beta, DNA and amino acid sequence and promoter determination and analysis. Transcriptional regulation of Pcyt2, overview
-
PfECT, sequence comparison, expression of N-terminally His6-tagged enzyme in Escherichia coli strain BL21(DE3)