Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphatidylglycerol | slightly stimulating | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetamide | - |
Rattus norvegicus | |
NEM | - |
Rattus norvegicus | |
oleate | - |
Rattus norvegicus | |
PCMB | - |
Rattus norvegicus | |
Sphingosine/phosphatidylcholine vesicles | inhibit cytosolic and purified enzyme | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | postmicrosomal supernatant | Rattus norvegicus | 5829 | - |
additional information | approximately 50% of the total activity is in the supernatant, the remainder being distributed among subcellular localizations | Rattus norvegicus | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
49600 | - |
x * 49600, SDS-PAGE | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + ethanolamine phosphate | Rattus norvegicus | rate-regulatory enzyme of phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway | diphosphate + CDP-ethanolamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
1430fold to homogeneity | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
6.505 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
CTP + ethanolamine phosphate | - |
Rattus norvegicus | diphosphate + CDP-ethanolamine | - |
? | |
CTP + ethanolamine phosphate | rate-regulatory enzyme of phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway | Rattus norvegicus | diphosphate + CDP-ethanolamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 49600, SDS-PAGE | Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Rattus norvegicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Rattus norvegicus | - |
- |
6.5 |