2.7.1.4: fructokinase
This is an abbreviated version!
For detailed information about fructokinase, go to the full flat file.
Word Map on EC 2.7.1.4
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2.7.1.4
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cyclosporine
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rejection
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allograft
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tacrolimus
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steroid
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opioids
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rapamycin
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keratitis
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enkephalin
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bowel
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naloxone
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forskolin
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corneal
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creatinine
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mycophenolate
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nephrotoxicity
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met-enkephalin
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mofetil
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postoperative
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calcineurin
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orthotopic
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invertase
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opiate
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morphine
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trough
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glucokinase
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azathioprine
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sirolimus
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heterotopic
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immunophilins
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posttransplant
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d-ala2
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readable
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allotransplantation
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beta-endorphin
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readability
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tachykinins
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medicine
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synthesis
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retransplantation
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donor-specific
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keratoplasty
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fractalkine
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actuarial
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hexokinases
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fructose-1-phosphate
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methionine-enkephalin
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steroid-resistant
- 2.7.1.4
-
cyclosporine
-
rejection
-
allograft
- tacrolimus
- steroid
-
opioids
- rapamycin
- keratitis
- enkephalin
- bowel
- naloxone
- forskolin
- corneal
- creatinine
- mycophenolate
-
nephrotoxicity
- met-enkephalin
- mofetil
-
postoperative
- calcineurin
-
orthotopic
- invertase
-
opiate
- morphine
-
trough
- glucokinase
- azathioprine
- sirolimus
-
heterotopic
-
immunophilins
-
posttransplant
-
d-ala2
-
readable
-
allotransplantation
- beta-endorphin
-
readability
- tachykinins
- medicine
- synthesis
-
retransplantation
-
donor-specific
-
keratoplasty
- fractalkine
-
actuarial
- hexokinases
- fructose-1-phosphate
- methionine-enkephalin
-
steroid-resistant
Reaction
Synonyms
At1g06020, At1g66430, At2g31390, At3g59480, At4g10260, At5g51830, AtFRK6, AtFRK7, CL6EHI_054510, cscK, D-fructokinase, D-fructose(D-mannose)kinase, FK, FK1, FK2, FRK, Frk1, Frk2, Frk3, Frk4, FRK5, FRK6, FRK7, fructokinase, Hore_18220, KHK, kinase, fructo- (phosphorylating), MdFRK1, MdFRK2, MEALZv4_0616, putative fructokinase, ROK FK, sacK1, Vc-FK, YdhR
ECTree
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Inhibitors
Inhibitors on EC 2.7.1.4 - fructokinase
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Mn2+
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can partially replace Mg2+ in activation, inhibition above 0.5 mM at 1 mM ATP
UTP
FRK1 activity decreases by 85% activity in the presence of 1 mM UTP; FRK2 activity decreases by 75% activity in the presence of 1 mM UTP; FRK3 activity decreases by 75% activity in the presence of 1 mM UTP
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inhibitory at concentrations higher than 10 mM, complete inactivation above 25 mM
ATP
50 mM, almost complete inhibition; 50 mM, almost complete inhibition
D-fructose
substrate inhibition above 1 mM; substrate inhibition above 1 mM; substrate inhibition above 1 mM; substrate inhibition above 1 mM; substrate inhibition above 1 mM
D-fructose
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above 0.4 mM at pH 8.2, no substrate inhibition at pH 6.6; substrate inhibition
D-fructose
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severe inhibition with fructokinase-Ia and-Ib, slight with fructokinase II; substrate inhibition
D-fructose
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D-isomer; hyperbolic-noncompetitive with respect to both substrates
D-fructose
SlFRK2 and SlFRK3, are substrate inhibited. FRK1 is not inhibited by fructose; substrate inhibition; substrate inhibition, SlFRK3
D-fructose
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isoenzyme FK-I: substrate inhibition at 4-8 mM, FK-II: substrate inhibition above 1 mM, FK-III: no substrate inhibition
FRK1 activity decreases by 35% activity in the presence of 1 mM GTP; FRK2 activity decreases by about 50% activity in the presence of 1 mM GTP; FRK3 activity decreases by about 50% activity in the presence of 1 mM GTP
Mg2+
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inhibition of FK1 above 1 mM, only little inhibition of FDIII, no inhibition of FKII
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
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no substrate inhibition by D-fructose (above 1 mM); no substrate inhibition by D-fructose (above 1 mM)
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additional information
not inhibitory: D-glucose, and Mg2+ up to 10 mM
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