2.7.1.4: fructokinase
This is an abbreviated version!
For detailed information about fructokinase, go to the full flat file.
Word Map on EC 2.7.1.4
-
2.7.1.4
-
cyclosporine
-
rejection
-
allograft
-
tacrolimus
-
steroid
-
opioids
-
rapamycin
-
keratitis
-
enkephalin
-
bowel
-
naloxone
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forskolin
-
corneal
-
creatinine
-
mycophenolate
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nephrotoxicity
-
met-enkephalin
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mofetil
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postoperative
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calcineurin
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orthotopic
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invertase
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opiate
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morphine
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trough
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glucokinase
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azathioprine
-
sirolimus
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heterotopic
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immunophilins
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posttransplant
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d-ala2
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readable
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allotransplantation
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beta-endorphin
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readability
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tachykinins
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medicine
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synthesis
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retransplantation
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donor-specific
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keratoplasty
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fractalkine
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actuarial
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hexokinases
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fructose-1-phosphate
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methionine-enkephalin
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steroid-resistant
- 2.7.1.4
-
cyclosporine
-
rejection
-
allograft
- tacrolimus
- steroid
-
opioids
- rapamycin
- keratitis
- enkephalin
- bowel
- naloxone
- forskolin
- corneal
- creatinine
- mycophenolate
-
nephrotoxicity
- met-enkephalin
- mofetil
-
postoperative
- calcineurin
-
orthotopic
- invertase
-
opiate
- morphine
-
trough
- glucokinase
- azathioprine
- sirolimus
-
heterotopic
-
immunophilins
-
posttransplant
-
d-ala2
-
readable
-
allotransplantation
- beta-endorphin
-
readability
- tachykinins
- medicine
- synthesis
-
retransplantation
-
donor-specific
-
keratoplasty
- fractalkine
-
actuarial
- hexokinases
- fructose-1-phosphate
- methionine-enkephalin
-
steroid-resistant
Reaction
Synonyms
At1g06020, At1g66430, At2g31390, At3g59480, At4g10260, At5g51830, AtFRK6, AtFRK7, CL6EHI_054510, cscK, D-fructokinase, D-fructose(D-mannose)kinase, FK, FK1, FK2, FRK, Frk1, Frk2, Frk3, Frk4, FRK5, FRK6, FRK7, fructokinase, Hore_18220, KHK, kinase, fructo- (phosphorylating), MdFRK1, MdFRK2, MEALZv4_0616, putative fructokinase, ROK FK, sacK1, Vc-FK, YdhR
ECTree
2.7.1.4 fructokinaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.7.1.4 - fructokinase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
to enter metabolism, fructose is phosphorylated by a fructokinase
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
no activity with ribose, xylose, fucose, glucose, tagatose or arabinose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
high specificity for fructose but no affinity for glucose
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
the first step in fructose metabolism is mediated by fructokinase
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose, both isoforms
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
sucrose to starch synthetic pathway
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
-
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
higher affinity for ATP than for other NTPs
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
best phosphate donor for isozymes FK-II and FK-III
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
fructose metabolism
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
sucrose to starch synthetic pathway
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
inducible enzyme
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
highly specific for D-fructose, minor products are D-fructose 2-phosphate and D-fructose-3 phosphate
-
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose
-
?
ATP + D-fructose
ADP + D-fructose 6-phosphate
-
specific for fructose and ATP
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
isoform FRK1, 1.6% of activity with D-fructose, isoform FRK2, 7.8% of activity with D-fructose
-
-
?
ATP + D-glucose
ADP + D-glucose 6-phosphate
-
isoenzyme FK-I and FK-II less than 5% of the activity with fructose
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
D-fructose and D-mannose phosphorylated at equivalent rates
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
isoform FRK1, 2.2% of activity with D-fructose, isoform FRK2, 2.4% of activity with D-fructose
-
-
?
ATP + D-mannose
ADP + D-mannose 6-phosphate
-
isoenzyme FK-I and FK-II low activity, less than 5% of D-fructose, FK-III no activity
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
6% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
higher activity than with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
40% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
isoform FRK1, 35% of activity with ATP, isoform FRK2, 83% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
16% of activity with ATP
-
-
?
CTP + D-fructose
CDP + D-fructose 6-phosphate
-
7.4times higher activity than with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
90% of the activity with ATP
-
-
?
dATP + D-fructose
dADP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
23% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
30% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
isoform FRK1, 23% of activity with ATP, isoform FRK2, 135% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
best phosphate donor for isozyme FK-I
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
50% of the activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
62% of activity with ATP
-
-
?
GTP + D-fructose
GDP + D-fructose 6-phosphate
-
3fold higher activity than with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
78% of activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
25% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
60% of the activity with ATP
-
-
?
ITP + D-fructose
IDP + D-fructose 6-phosphate
-
73% of activity with ATP
-
-
?
TTP + D-fructose
TDP + D-fructose 6-phosphate
-
0.18% of activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
higher activity than with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
80% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
isoform FRK1, 39% of activity with ATP, isoform FRK2, 84% of activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
20% of the activity with ATP
-
-
?
UTP + D-fructose
UDP + D-fructose 6-phosphate
-
16% of activity with ATP
-
-
?
additional information
?
-
no substrates: glucose, galactose
-
-
?
additional information
?
-
-
very low activity as phosphate donors: dGTP, TTP, XTP
-
-
?
additional information
?
-
-
discussion of possible significance of the enzyme in plant carbohydrate metabolism
-
-
?
additional information
?
-
-
no substrate: ADP, GDP, phosphoenolpyruvate, diphosphate
-
-
?
