Disease on EC 2.7.1.4 - fructokinase
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Acromegaly
Disturbed prolactin responses to dopamine-related substances in patients with acromegaly and hyperprolactinemia.
Acromegaly
Plasma LH, FSH and TSH responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Acromegaly
Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Acute Kidney Injury
Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice.
Acute Kidney Injury
The sweetest thing: blocking fructose metabolism to prevent acute kidney injury?
Acute Kidney Injury
[Pancreas transplant pathology: clinicopathologic and experimental findings]
Addison Disease
Effects of a met-enkephalin analog on adrenocorticotropin (ACTH), growth hormone, and prolactin in patients with ACTH hypersecretion.
Addison Disease
Effects of ovine corticotropin-releasing hormone and FK 33-824 (met-enkephalin analogue) on the secretions of proopiomelanocortin-derived N-terminal peptide, beta-lipotropin, beta-endorphin and adrenocorticotropin in patients with Addison's disease.
Adenocarcinoma
Clinical pharmacology of 11-acetyl-8-carbamoyloxymethyl-4-formyl-14-oxa-1,11-diazatetracyclo (7.4.1.0(2,7).0(10,12) tetradeca-2,4,6-trien-6,9-diyl diacetate (FK 973).
Adenoma
FK 33-824, a met-enkephalin analog, blocks corticotropin-releasing hormone-induced adrenocorticotropin secretion in normal subjects but not in patients with Cushing's disease.
Alopecia
Hair growth modulation by topical immunophilin ligands: induction of anagen, inhibition of massive catagen development, and relative protection from chemotherapy-induced alopecia.
Alopecia Areata
Differential effects of FK 506 and cyclosporine on hair regrowth in the DEBR model of alopecia areata.
Anemia, Hemolytic
Acute hemolytic anemia in liver and bone marrow transplant patients under FK 506 therapy.
Aphasia
Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Arthritis
Characterisation of passively transferred antigen arthritis induced by methylated bovine serum albumin in the rat: effect of FK 506 on arthritis development.
Arthritis, Experimental
Effect of FK 506 (FR 900506) on collagen arthritis in rats: a preliminary report.
Aspergillosis
The spectrum of aspergillosis in liver transplant patients: comparison of FK 506 and cyclosporine immunosuppression.
Asthma
Steroid withdrawal in tacrolimus (FK506)-treated pediatric liver transplant recipients.
Asthma
[Inhibitory effect of inhaled FK-506 on increased bronchial responsiveness and eosinophil infiltration in the airway mucosa]
Atherosclerosis
Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.
Atherosclerosis
Functional analysis of the fractalkine gene promoter in human aortic smooth muscle cells exposed to proinflammatory conditions.
Autoimmune Diseases
FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh.
Autoimmune Diseases
Functional and structural characteristics of experimental FK 506 nephrotoxicity.
Bacterial Infections
A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation.
Bacterial Infections
Effect of RS61443 in combination with leflunomide or FK506 on rat heart allograft survival.
Bacterial Infections
Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis.
Blepharitis
[FK 506 ointment 0.1 % - A new therapeutic option for atopic blepharitis. Clinical trial with 14 patients]
Blindness
Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model.
Bradycardia
Addition of Low-Dose Ketamine to Propofol-Fentanyl Sedation for Gynecologic Diagnostic Laparoscopy: Randomized Controlled Trial.
Bradycardia
Cardiorespiratory effects of D-Ala-2-Me-Phe-4-Met-(0)-ol enkephalin in the third ventricle, and in anterior hypothalamic and paraventricular areas of the rat brain.
Bradycardia
Cardiorespiratory responses to D-Ala-2-Me-Phe-4-Met-(O)-ol-enkephalin after administration into the fourth cerebral ventricle of the rat: interaction with cholinergic mechanisms.
Bradycardia
Perfusion of the fourth cerebral ventricle with the synthetic opioid peptide, FK 33-824, induces dose-related bradycardia and naloxone-reversible respiratory depression in the awake dog.
Brain Edema
A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation.
Brain Ischemia
[The effect of FK 506, an immunosuppressant, on cerebral infarction volume in focal cerebral ischemia in rats]
Bronchiolitis
FK 506 'rescue' immunosuppression for obliterative bronchiolitis after lung transplantation.
Bronchiolitis Obliterans
FK 506 'rescue' immunosuppression for obliterative bronchiolitis after lung transplantation.
Carcinogenesis
Effect of bile acids and dietary fat on large bowel carcinogenesis in animal models.
Carcinoma
Chemoattraction, adhesion and activation of natural killer cells are involved in the antitumor immune response induced by fractalkine/CX3CL1.
Carcinoma
Fractalkine transgene induces T-cell-dependent antitumor immunity through chemoattraction and activation of dendritic cells.
Carcinoma, Hepatocellular
A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation.
Carcinoma, Hepatocellular
Gene therapy with CX3CL1/Fractalkine induces antitumor immunity to regress effectively mouse hepatocellular carcinoma.
Carcinoma, Hepatocellular
[Activity of enzymes of glycolysis and gluconeogenesis in primary hepatomas induced by diethylnitrosamine]
Carcinoma, Hepatocellular
[Experimental gene therapy mediated by fractalkine (FK) for murine liver cancer]
Catatonia
Strain dependent effects of the enkephalin analogue FK 33-824 on locomotor activity in mice.
Cerebral Infarction
[The effect of FK 506, an immunosuppressant, on cerebral infarction volume in focal cerebral ischemia in rats]
Coma
Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Congenital Abnormalities
[A clinical radiological score for femoral head grafts : Establishment of the Tabea FK score to ensure the quality of human femoral head grafts].
Contracture
Neural activation of opioid mechanisms in guinea pig ileum by excitatory peptides.
Corneal Injuries
Expression and potential role of major inflammatory cytokines in experimental keratomycosis.
Corneal Injuries
MSCs helped reduce scarring in the cornea after fungal infection when combined with anti-fungal treatment.
Corneal Opacity
MSCs helped reduce scarring in the cornea after fungal infection when combined with anti-fungal treatment.
Corneal Perforation
Mast Cell Activation Protects Cornea by Promoting Neutrophil Infiltration via Stimulating ICAM-1 and Vascular Dilation in Fungal Keratitis.
Corneal Ulcer
Conjunctival microbiome changes associated with fungal keratitis: metagenomic analysis.
Coronary Artery Disease
Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.
Coronary Artery Disease
Does FK 506 accelerate the development of coronary artery disease in the transplanted heart as well as the native heart?
Coronary Artery Disease
Graft coronary arteriosclerosis in rat heart transplant model with FK 506 short-term administration.
Coronary Artery Disease
Suppressive effects of combination therapy with mizoribine and FK 506 on the development of accelerated coronary artery disease and myocardial rejection after heart transplantation.
Cough
Angiotensin-converting enzyme inhibitor and danazol increase sensitivity of cough reflex in female guinea pigs.
Cough
The pharmacological characterization of FK 739, a new angiotensin II-receptor antagonist.
Crohn Disease
Oral tacrolimus (FK 506) in Crohn's disease complicated by fistulae of the perineum.
Cushing Syndrome
Effects of a met-enkephalin analog on adrenocorticotropin (ACTH), growth hormone, and prolactin in patients with ACTH hypersecretion.
Cushing Syndrome
FK 33-824, a met-enkephalin analog, blocks corticotropin-releasing hormone-induced adrenocorticotropin secretion in normal subjects but not in patients with Cushing's disease.
Dehydration
A novel method for determining rate constants for dehydration of aldehyde hydrates.
Dehydration
Changes in leaf hexokinase activity and metabolite levels in response to drying in the desiccation-tolerant species Sporobolus stapfianus and Xerophyta viscosa.
Dehydration
Identification of proteins regulated by cross-talk between drought and hormone pathways in Arabidopsis wild-type and auxin-insensitive mutants, axr1 and axr2.
Dehydration
Rehydration with Soft Drink-like Beverages Exacerbates Dehydration and Worsens Dehydration-associated Renal Injury.
Demyelinating Diseases
Immunoaugmenting effect of FK 506 on experimental allergic encephalomyelitis in Lewis rats.
Dermatitis
Scratching behavior does not necessarily correlate with epidermal nerve fiber sprouting or inflammatory cell infiltration.
Dermatitis, Allergic Contact
Anti-Inflammatory Effects of Macrophilin-lnteracting Drugs in Animal Models of Irritant and Allergic Contact Dermatitis.
Dermatitis, Allergic Contact
Horizons in pharmacologic intervention in allergic contact dermatitis.
Dermatitis, Allergic Contact
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases?
Dermatitis, Atopic
[FK 506 ointment 0.1 % - A new therapeutic option for atopic blepharitis. Clinical trial with 14 patients]
Dermatitis, Contact
Tacrolimus enhances irritation in a 5-day human irritancy in vivo model.
Dermatitis, Irritant
Anti-Inflammatory Effects of Macrophilin-lnteracting Drugs in Animal Models of Irritant and Allergic Contact Dermatitis.
Diabetes Mellitus
Complete reversal of FK 506 induced diabetes in a liver transplant recipient by change of immunosuppression to cyclosporine A.
Diabetes Mellitus
Corticosteroids and concomitant medication in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Diabetes Mellitus
Diabetes mellitus after renal transplantation under FK 506 (tacrolimus) as primary immunosuppression.
Diabetes Mellitus
Disappearance of diabetes mellitus after conversion from FK 506 to Neoral in two liver transplanted patients.
Diabetes Mellitus
FK 506-associated diabetes mellitus in the pediatric transplant population is a rare complication.
Diabetes Mellitus
Glucose metabolism in liver transplant recipients treated with FK 506 or cyclosporin in the European multicentre study.
Diabetes Mellitus
Posttransplant diabetes mellitus in African Americans after renal transplantation under FK 506 immunosuppression.
Diabetes Mellitus, Experimental
Response of hepatic fructokinase to long-term sucrose diets and diabetes in spiny mice, albino mice and rats.
Diabetes Mellitus, Type 1
-to: Pani MA, Van Autreve J, Van der Auwera BJ, Gorus FK, Badenhoop K (2002) Non-transmitted maternal HLA DQ2 or DQ8 alleles and risk of Type 1 diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 45:1340-1343.
Diabetes Mellitus, Type 1
Comparison of short and long-term renal function in liver transplant patients receiving cyclosporin or FK 506.
Diabetes Mellitus, Type 2
Correction to: Apolipoprotein C3Gene Variants and Risk of Developing Type 2 Diabetes in Saudi Subjects by Alharbi KK, Hussain T, Alharbi FK, Tabassum SN, Mohammed AA, Gambhir D, and Khan IA. Metab Syndr Relat Disord 2015;13;7;298-303 DOI:10.1089/met.2015.0022.
Diabetic Nephropathies
Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy.
Drug-Related Side Effects and Adverse Reactions
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression.
Drug-Related Side Effects and Adverse Reactions
New approaches in the use of cyclosporine: with particular reference to the liver.
Drug-Related Side Effects and Adverse Reactions
The immunomodulatory effects of a novel agent, leflunomide, in rat cardiac allotransplantation.
Dwarfism, Pituitary
Plasma LH, FSH and TSH responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Dwarfism, Pituitary
Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Encephalomyelitis
Immunoaugmenting effect of FK 506 on experimental allergic encephalomyelitis in Lewis rats.
Encephalomyelitis, Autoimmune, Experimental
Effects of FK 506 on acute experimental allergic encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Immunoaugmenting effect of FK 506 on experimental allergic encephalomyelitis in Lewis rats.
Encephalomyelitis, Autoimmune, Experimental
The ability of myelin basic protein-sensitised leukocytes to adoptively transfer experimental allergic encephalomyelitis following coculture with FK 506, cyclosporine, or prednisolone.
Encephalomyelitis, Autoimmune, Experimental
[Effects of novel immunosuppressant FK 506 in acute experimental allergic encephalomyelitis]
Endophthalmitis
Arthrographis kalrae Keratitis Complicated by Endophthalmitis: A Case Report With Literature Review.
Endotoxemia
Evidence that FK506 alleviates ischemia/reperfusion injury to the rat liver: in vivo demonstration for suppression of TNF-a production in response to endotoxemia.
Endotoxemia
Fructokinase, Fructans, Intestinal Permeability, and Metabolic Syndrome: An Equine Connection?
Enteritis
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients.
Eosinophilia
Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient.
Epilepsy
Absence of seizure activity following focal cerebral injection of enkephalins in a primate.
Epilepsy
Acetone as biomarker for ketosis buildup capability--a study in healthy individuals under combined high fat and starvation diets.
Esophageal Achalasia
Laparoscopic Heller myotomy and Dor fundoplication for the treatment of achalasia. Assessment in relation to morphologic type.
Essential Hypertension
Antihypertensive effect of a new calcium channel blocker, FK 235, in essential hypertension.
Fasciitis, Necrotizing
Necrotizing fasciitis in a renal transplant recipient treated with FK 506: the first reported case.
Fatty Liver
High fat and high sucrose (western) diet induce steatohepatitis that is dependent on fructokinase.
Fatty Liver
Synergistic effect of uricase blockade plus physiological amounts of fructose-glucose on glomerular hypertension and oxidative stress in rats.
Fatty Liver
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.
Favism
[New acquisitions on the subject of the bio-enzymology of ictero-hemoglobinuric favism. Note I. The enolase, fructokinase and phosphofructokinase activity of the erythrocytes.]
Fetal Growth Retardation
Windows of therapeutic opportunity on fetal growth retardation induced by transient intrauterine ischemia in rats.
fructokinase deficiency
Cyclical dehydration-induced renal injury and Mesoamerican nephropathy: as sweet by any other name?
fructose-bisphosphatase deficiency
Inborn Errors of Fructose Metabolism. What Can We Learn from Them?
Gingival Hyperplasia
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression.
Glomerulonephritis
Effect of a novel immunosuppressant, FK 506, on autoimmune glomerulonephritis in Brown Norway rats.
Glomerulonephritis
Effect of FK 506 in the prophylaxis of autoimmune glomerulonephritis in NZB/WF1 mice.
Glomerulonephritis
Effect of FK 506 in the treatment of autoimmune glomerulonephritis in Brown Norway rats.
Glomerulonephritis
FK 506 in steroid-resistant focal sclerosing glomerulonephritis of childhood.
Glomerulonephritis, Membranous
De novo membranous glomerulopathy in a renal transplant patient treated with FK 506. The first reported case.
Glomerulosclerosis, Focal Segmental
FK 506 in steroid-resistant focal sclerosing glomerulonephritis of childhood.
Glucose Intolerance
Liver AMP/ATP ratio and fructokinase expression are related to gender differences in AMPK activity and glucose intolerance in rats ingesting liquid fructose.
Glucose Intolerance
Metabolic effects of cyclosporin A and FK 506 in liver transplant recipients.
Graft vs Host Disease
Addition of the colon to small bowel grafts causes lethal graft-versus-host disease in FK 506-treated pigs.
Graft vs Host Disease
Clinical outcome after conversion to FK 506 (tacrolimus) therapy for acute graft-versus-host disease resistant to cyclosporine or for cyclosporine-associated toxicities.
Graft vs Host Disease
FK 506 inhibits severe graft-versus-host disease without mediating cytokine balance and/or cytotoxic molecules.
Graft vs Host Disease
FK 506 reverses acute graft-versus-host disease after allogeneic bone marrow transplantation in rats.
Graft vs Host Disease
FK 506-based immunosuppression for prevention of graft versus host disease after unrelated donor marrow transplantation.
Graft vs Host Disease
Fulminant graft-versus-host disease after FK 506 treatment in fully allogeneic small bowel transplantation.
Graft vs Host Disease
Immunosuppressive power and limitations of FK 506 for prevention and treatment of graft-vs-host disease after small bowel transplantation.
Graft vs Host Disease
Prolonged prevention of acute graft-versus-host disease after allogeneic bone marrow transplantation by donor pretreatment using FK 506.
Hallucinations
Acute effects of the synthetic analogue of methionine enkephalin FK 33-824 in schizophrenic patients. A double blind trial.
Hallucinations
Ketamine and lornoxicam for preventing a fentanyl-induced increase in postoperative morphine requirement.
Heart Arrest
A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation.
Heart Failure
Altered interaction of FKBP12.6 with ryanodine receptor as a cause of abnormal Ca(2+) release in heart failure.
Heart Failure
Diabetic Cardiomyopathy: The Case for a Role of Fructose in Disease Etiology.
Heart Failure
Sarcoplasmic reticulum calcium release function and FK binding proteins in heart failure: another piece of a complex jigsaw.
Hemolytic-Uremic Syndrome
FK 506 as an alternative in cyclosporin-induced hemolytic uremic syndrome in a kidney transplant recipient.
Hemolytic-Uremic Syndrome
Hemolytic-uremic syndrome in a renal transplant recipient on FK 506 immunosuppression.
Hemolytic-Uremic Syndrome
Renal transplantation under cyclosporine and FK 506 for hemolytic uremic syndrome.
Hemolytic-Uremic Syndrome
Renal transplantation under FK 506 in patients with previous loss of renal function due to hemolytic uremic syndrome.
Hepatitis
Interferon therapy of hepatitis following liver transplantation under FK 506 or cyclosporine.
Hepatitis
[BEHAVIOR OF FRUCTOSE AND INORGANIC PHOSPHORUS FOLLOWING ORAL SACCHAROSE LOAD AS AN INDEX OF FRUCTOSE METABOLISM. FRUCTOKINASE ACTIVITY OF THE LIVER IN VIRAL HEPATITIS.]
Hepatitis C
A randomized, prospective, pharmacoeconomic trial of neoral 2-hour postdose concentration monitoring versus tacrolimus trough concentration monitoring in de novo liver transplant recipients.
Hepatitis C
Four-year follow-up of a prospective randomized trial of mycophenolate mofetil with cyclosporine microemulsion or tacrolimus following liver transplantation.
Hepatitis C
Increased rejection after liver transplantation in FK 506-treated patients is associated with viral hepatitis C disease.
Hepatitis C
Influence of hepatitis C virus infection on FK 506 blood levels in renal transplant patients.
Hepatitis C
Severe neurotoxicity after liver transplantation: association between FK 506 therapy and hepatitis C virus disease.
Hirsutism
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression.
Hypercholesterolemia
Hypercholesterolemia in long-term survivors of liver transplantation: a comparison between cyclosporine and FK 506.
Hypercholesterolemia
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506.
Hyperglycemia
Islet cell damage associated with tacrolimus and cyclosporine: morphological features in pancreas allograft biopsies and clinical correlation.
Hyperglycemia
Japanese study of FK 506 on kidney transplantation: 2. Follow-up study of FK 506-treated patients.
Hyperkalemia
Comparison of short and long-term renal function in liver transplant patients receiving cyclosporin or FK 506.
Hyperprolactinemia
Disturbed prolactin responses to dopamine-related substances in patients with acromegaly and hyperprolactinemia.
Hyperprolactinemia
Plasma LH, FSH and TSH responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Hyperprolactinemia
Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Hypersensitivity
Comparison of topical dexamethasone and topical FK506 treatment for the experimental allergic conjunctivitis model in BALB/c mice.
Hypersensitivity
Immunosuppressive effect of FK 506 on cytotoxic T lymphocytes and delayed-type hypersensitivity in rats.
Hypersensitivity
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases?
Hypertension
A decade (1982 to 1992) of pediatric cardiac transplantation and the impact of FK 506 immunosuppression.
Hypertension
A prospective trial of tacrolimus (FK 506) in clinical heart transplantation: intermediate-term results.
Hypertension
Comparison of short and long-term renal function in liver transplant patients receiving cyclosporin or FK 506.
Hypertension
Effect of FK 506 on the expression of endothelin receptor mRNA in the vasculature.
Hypertension
FK 506 versus cyclosporin in the prevention of renal allograft rejection--European pilot study: six-week results.
Hypertension
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506.
Hypertension
Optimal FK 506 dosage in patients under primary immunosuppression following liver transplantation.
Hypertension
Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506.
Hypertension
Renal complications and development of hypertension in the European study of FK 506 and cyclosporin in primary liver transplant recipients.
Hypertension
Study on the mechanisms of glucocorticoid-induced hypertension: glucocorticoids increase transmembrane Ca2+ influx in vascular smooth muscle in vivo.
Hypertension
Tailored dialysis start may allow persistence of residual renal function after graft failure: a case report.
Hypertension
The pharmacological characterization of FK 739, a new angiotensin II-receptor antagonist.
Hypertension, Portal
FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway.
Hypotension
Cardiorespiratory effects of D-Ala-2-Me-Phe-4-Met-(0)-ol enkephalin in the third ventricle, and in anterior hypothalamic and paraventricular areas of the rat brain.
Hypotension
Cardiorespiratory responses to D-Ala-2-Me-Phe-4-Met-(O)-ol-enkephalin after administration into the fourth cerebral ventricle of the rat: interaction with cholinergic mechanisms.
Infections
A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment.
Infections
A prospective randomized trial of mycophenolate mofetil with neoral or tacrolimus after orthotopic liver transplantation.
Infections
Acute rejection and heart infection rates in FK 506- versus cyclosporine A-treated heart transplant recipients: an endomyocardial biopsy pathologic study.
Infections
Analysis of time-dependent risks for infection, rejection, and death after pulmonary transplantation.
Infections
Antimicrobial peptides in human corneal tissue of patients with fungal keratitis.
Infections
CMV infection in liver transplantation under cyclosporine or FK 506 immunosuppression.
Infections
Comparison of antibacterial activity of a new cephalosporin, ceftizoxime (FK 749) with other cephalosporin antibiotics.
Infections
Cytomegalovirus infection of the upper gastrointestinal tract following liver transplantation--incidence, location, and severity in cyclosporine- and FK506-treated patients.
Infections
Early steroid withdrawal in pediatric renal transplantation at a single center: preliminary report.
Infections
Evaluation of Liposomal and Conventional Amphotericin B in Experimental Fungal Keratitis Rabbit Model.
Infections
FK 506 primary immunosuppression following emergency liver transplantation for fulminant hepatic failure. European FK 506 Study Liver Group.
Infections
FK 506 versus cyclosporin in the prevention of renal allograft rejection--European pilot study: six-week results.
Infections
Four-year follow-up of a prospective randomized trial of mycophenolate mofetil with cyclosporine microemulsion or tacrolimus following liver transplantation.
Infections
High incidence of severe infections in heart transplant recipients receiving tacrolimus.
Infections
In vitro and in vivo antibacterial properties of FK 027, a new orally active cephem antibiotic.
Infections
Infections during a randomized trial comparing cyclosporine to FK 506 immunosuppression in liver transplantation.
Infections
Infections with FK 506 immunosuppression: preliminary results with primary therapy.
Infections
Inhibition of human immunodeficiency virus and growth of infected T cells by the immunosuppressive drugs cyclosporin A and FK 506.
Infections
Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients.
Infections
Postoperative selective bowel decontamination prevents gram-negative bacterial translocation in small-bowel graft recipients.
Infections
Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506.
Infections
Recipient FK506 pretreatment regimens in rat small bowel transplantation: allograft survival, function, and systemic infection.
Insulin Resistance
Cacao extract enriched in polyphenols prevents endocrine-metabolic disturbances in a rat model of prediabetes triggered by a sucrose rich diet.
Insulin Resistance
Effect of CsA versus FK 506 on insulin sensitivity and insulin response using a modeling technique.
Insulin Resistance
Fructokinase, Fructans, Intestinal Permeability, and Metabolic Syndrome: An Equine Connection?
Keratitis
Altered Patterns of Fungal Keratitis at a London Ophthalmic Referral Hospital: An Eight-Year Retrospective Observational Study.
Keratitis
Antimicrobial peptides in human corneal tissue of patients with fungal keratitis.
Keratitis
Baicalein Protects Against Aspergillus fumigatus Keratitis by Reducing Fungal Load and Inhibiting TSLP-Induced Inflammatory Response.
Keratitis
Comparison of fungal and bacterial keratitis between tropical and subtropical Taiwan: a prospective cohort study.
Keratitis
Diagnostic Evaluation of Co-Occurrence of Acanthamoeba and Fungi in Keratitis: A Preliminary Report.
Keratitis
Isorhamnetin Ameliorates Aspergillus fumigatus Keratitis by Reducing Fungal Load, Inhibiting Pattern-Recognition Receptors and Inflammatory Cytokines.
Keratitis
Lipoxin A4 activates ALX/FPR2 to attenuate inflammation in Aspergillus fumigatus keratitis.
Keratitis
Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States.
Keratitis
Quercetin amelioratesAspergillus fumigatuskeratitis by inhibiting fungal growth, toll-like receptors and inflammatory cytokines.
Keratitis
Topical Corticosteroids for Infectious Keratitis Before Culture-Proven Diagnosis.
Kidney Diseases
The sweetest thing: blocking fructose metabolism to prevent acute kidney injury?
Leukoencephalopathies
FK 506-induced fulminant leukoencephalopathy after kidney transplantation: case report.
Liver Diseases
Comparison of different assays for the quantitation of FK 506 levels in blood or plasma.
Liver Diseases
Plasma level-guided low-dose FK 506 therapy in patients with early liver dysfunction after liver transplantation.
Liver Diseases
Single-center experience with primary orthotopic liver transplantation with FK 506 immunosuppression.
Liver Failure, Acute
FK 506 primary immunosuppression following emergency liver transplantation for fulminant hepatic failure. European FK 506 Study Liver Group.
Lupus Nephritis
Analysis of cytochrome P450 gene polymorphism in a lupus nephritis patient in whom tacrolimus blood concentration was markedly elevated after administration of azole antifungal agents.
Lymphocytosis
Comparative effects of rapamycin, FK 506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat.
Lymphoma
Establishment of Epstein-Barr virus-associated lymphoma cell line SUBL with t(2;3)(p11;q27) from a liver transplant patient.
Lymphoproliferative Disorders
Lymphoproliferative disorder in a liver transplant patient on FK 506.
Lymphoproliferative Disorders
Lymphoproliferative disorders arising under immunosuppression with FK 506: initial observations in a large transplant population.
Lymphoproliferative Disorders
Posttransplant lymphoproliferative disorders occurring under primary FK 506 immunosuppression.
Metabolic Syndrome
Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction.
Metabolic Syndrome
Fructokinase, Fructans, Intestinal Permeability, and Metabolic Syndrome: An Equine Connection?
Metabolic Syndrome
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Metabolic Syndrome
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake.
Metabolic Syndrome
Sugar causes obesity and metabolic syndrome in mice independently of sweet taste.
Multiple Sclerosis
Incidence of CD4+ IL-2R alpha+ and CD4+ CD45RA+ T-cells in progressive multiple sclerosis and the influence of short-term (3 months) FK 506 therapy.
Multiple Sclerosis
Influence of FK 506 (tacrolimus) on circulating CD4+ T cells expressing CD25 and CD45RA antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial.
Multiple Sclerosis
[Current therapy of multiple sclerosis: value of cyclosporin A and FK 506]
Multiple Sclerosis, Chronic Progressive
Influence of FK 506 (tacrolimus) on circulating CD4+ T cells expressing CD25 and CD45RA antigens in 19 patients with chronic progressive multiple sclerosis participating in an open label drug safety trial.
Myasthenia Gravis
Benefits of FK 506 for refractory eye symptoms in a young child with ocular myasthenia gravis.
Mycoses
Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis.
Mycoses
Reducing mortality associated with immediate treatment complications of adult leukemias.
Mycoses
Therapeutic effects of an anti-IL-6 antibody in fungal keratitis: Macrophage inhibition and T cell subset regulation.
Myocarditis
Pharmacotherapy of dilated cardiomyopathy: current status and future directions.
Neoplasms
A comparative study on immunosuppressive effects of cyclosporin A and FK 506 on peripheral blood lymphocytes in dogs.
Neoplasms
A fusion fragment from Flt-1 and KDR, acted as VEGF decoy receptor and exhibited anti-tumor function
Neoplasms
A fusion fragment from Flt-1 and KDR, acted as VEGF decoy receptor and exhibited anti-tumor function.
Neoplasms
Chemoattraction, adhesion and activation of natural killer cells are involved in the antitumor immune response induced by fractalkine/CX3CL1.
Neoplasms
Dynamic testing of prolactin and growth hormone secretion in patients with neuroendocrine disorders.
Neoplasms
FK 506 ameliorates normothermic liver ischemia in rats by suppressing production of tumor necrosis factor.
Neoplasms
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion.
Neoplasms
Fractalkine transgene induces T-cell-dependent antitumor immunity through chemoattraction and activation of dendritic cells.
Neoplasms
Gene therapy with CX3CL1/Fractalkine induces antitumor immunity to regress effectively mouse hepatocellular carcinoma.
Neoplasms
Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption.
Neoplasms
The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62.
Neoplasms
Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine.
Nephrosis, Lipoid
FK 506 for vascular permeability factor production in minimal change nephrotic syndrome.
Nephrotic Syndrome
FK 506 for vascular permeability factor production in minimal change nephrotic syndrome.
Nephrotic Syndrome
FK 506 in the management of nephrotic syndrome after renal transplantation.
Nephrotic Syndrome
FK 506 in the management of transplant-related nephrotic syndrome and steroid-resistant nephrotic syndrome.
Nephrotic Syndrome
Pilot trial of FK 506 in the management of steroid-resistant nephrotic syndrome.
Nervous System Diseases
FK 506 versus cyclosporin in the prevention of renal allograft rejection--European pilot study: six-week results.
Neurodegenerative Diseases
Distribution of immunophilin FKBP-12 protein and mRNA within the mammalian cochlea and cochlear nucleus.
Neurofibroma
Mast cells migrate, but do not degranulate, in response to fractalkine, a membrane-bound chemokine expressed constitutively in diverse cells of the skin.
Neurologic Manifestations
Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy.
Neutropenia
[Use of Sirolimus in five pediatric patients undergoing solid organ transplantation]
Non-alcoholic Fatty Liver Disease
Fructose consumption as a risk factor for non-alcoholic fatty liver disease.
Obesity
High fat and high sucrose (western) diet induce steatohepatitis that is dependent on fructokinase.
Ocular Hypertension
[Comment on Velten IM, Bergua A, Horm FK, Junemann A, Korth M. "Central corneal thickness in normal probands, patients with ocular hypertension, normal pressure and open-angle glaucomas--a clinical study"]
Oliguria
Corticosteroids and concomitant medication in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Opportunistic Infections
FK 506 therapy for refractory renal allograft rejection: lessons from liver transplantation.
Paralysis
[Comment on Beller FK. Incidence and causes of upper arm plexus paralysis in newborn infants. An overview and basic principles of legal considerations]
Paresis
Transient diffusion-weighted imaging changes in a patient with reversible leukoencephalopathy syndrome.
Pituitary ACTH Hypersecretion
Effects of a met-enkephalin analog on adrenocorticotropin (ACTH), growth hormone, and prolactin in patients with ACTH hypersecretion.
Pituitary ACTH Hypersecretion
FK 33-824, a met-enkephalin analog, blocks corticotropin-releasing hormone-induced adrenocorticotropin secretion in normal subjects but not in patients with Cushing's disease.
Pituitary Diseases
Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Pituitary Neoplasms
Effects of a met-enkephalin analog on adrenocorticotropin (ACTH), growth hormone, and prolactin in patients with ACTH hypersecretion.
Pituitary Neoplasms
Plasma LH, FSH and TSH responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Pituitary Neoplasms
Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases.
Pleurisy
Characterization of the receptor and the mechanisms underlying the inflammatory response induced by des-Arg9-BK in mouse pleurisy.
Pneumonia, Bacterial
A prospective randomized trial of FK506 versus cyclosporine after human pulmonary transplantation.
Pneumoperitoneum
Addition of Low-Dose Ketamine to Propofol-Fentanyl Sedation for Gynecologic Diagnostic Laparoscopy: Randomized Controlled Trial.
Polyneuropathies
[Acute peripheral demyelinating polyneuropathy and acute renal failure after administration of FK506]
Porcine Reproductive and Respiratory Syndrome
Persistence of Innate Immune Pathways in Late Stage Human Bacterial and Fungal Keratitis: Results from a Comparative Transcriptome Analysis.
Prolactinoma
Persistence of a defective tuberoinfundibular dopaminergic function in rats after long-term removal of oestrogen treatment. An in vivo study.
Proteinuria
Effect of a novel immunosuppressant, FK 506, on autoimmune glomerulonephritis in Brown Norway rats.
Proteinuria
Effect of FK 506 in the treatment of autoimmune glomerulonephritis in Brown Norway rats.
Proteinuria
Pilot trial of FK 506 in the management of steroid-resistant nephrotic syndrome.
Psoriasis
ICAM-1 and E-selectin expression in lesional biopsies of psoriasis patients responding to systemic FK 506 therapy.
Psoriasis
Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases.
Psoriasis
Systemic tacrolimus (FK 506) is effective for the treatment of psoriasis in a double-blind, placebo-controlled study. The European FK 506 Multicentre Psoriasis Study Group.
Psoriasis
The effect of cyclosporin A and FK 506 on the cAMP content in psoriatic keratinocytes.
Pyelonephritis
Pronounced renal vasoconstriction and systemic hypertension in renal transplant patients treated with cyclosporin A versus FK 506.
Pyoderma Gangrenosum
Efficacy of FK 506 in the treatment of recalcitrant pyoderma gangrenosum.
Renal Insufficiency
Comparison of short and long-term renal function in liver transplant patients receiving cyclosporin or FK 506.
Renal Insufficiency
Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK 506-treated patients.
Renal Insufficiency
Pharmacokinetics of cefixime (CL 284,635; FK 027) in healthy subjects and patients with renal insufficiency.
Reperfusion Injury
A spontaneous nitric oxide donor ameliorates small bowel ischemia-reperfusion injury in dogs.
Reperfusion Injury
Ameliorative effect of FK 506 on cold ischemia reperfusion injury of the rat liver.
Reperfusion Injury
Beneficial effects of FK409, a novel nitric oxide donor, on reperfusion injury of rat liver.
Reperfusion Injury
FK 506 ameliorates normothermic liver ischemia in rats by suppressing production of tumor necrosis factor.
Reperfusion Injury
Modulation of endothelin and nitric oxide: a rational approach to improve canine hepatic microcirculation.
Reperfusion Injury
NO donor ameliorates ischemia-reperfusion injury of the rat liver with iNOS attenuation.
Reperfusion Injury
Prior induction of heat shock proteins by a nitric oxide donor attenuates cardiac ischemia/reperfusion injury in the rat.
Reperfusion Injury
The effect of a selective cyclooxygenase-2 inhibitor in extended liver resection with ischemia in dogs.
Reperfusion Injury
The effect of cyclooxygenase-2 inhibitor FK3311 on ischemia-reperfusion injury in a canine total hepatic vascular exclusion model.
Reperfusion Injury
The effects of a cyclooxygenase-2 inhibitor, FK3311, on total hepatic ischemia-reperfusion injury of the rat.
Reperfusion Injury
The effects of a selective cyclooxygenase-2 inhibitor on small bowel ischemia-reperfusion injury.
Respiratory Insufficiency
Addition of Low-Dose Ketamine to Propofol-Fentanyl Sedation for Gynecologic Diagnostic Laparoscopy: Randomized Controlled Trial.
Respiratory Insufficiency
Cardiorespiratory responses to D-Ala-2-Me-Phe-4-Met-(O)-ol-enkephalin after administration into the fourth cerebral ventricle of the rat: interaction with cholinergic mechanisms.
Respiratory Insufficiency
D-Ala-2-Me-Phe-4-Met-(O)-ol-enkephalin in the nucleus tractus solitarius of the rat produces cardiorespiratory depression.
Respiratory Insufficiency
Effects of the enkephalin analogue FK33-824 on rectal temperature and respiratory rate in male mice.
Respiratory Insufficiency
Perfusion of the fourth cerebral ventricle with the synthetic opioid peptide, FK 33-824, induces dose-related bradycardia and naloxone-reversible respiratory depression in the awake dog.
Seizures
Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Seizures
Successful therapy for cerebral phaeohyphomycosis due to Dactylaria gallopava in a liver transplant recipient.
Sepsis
Cyclosporine withdrawal for nephrotoxicity in liver transplant recipients does not result in sustained improvement in kidney function and causes cellular and ductopenic rejection.
Sepsis
Single-center experience with primary orthotopic liver transplantation with FK 506 immunosuppression.
Skin Diseases
Immunosuppressive macrolides of the type FK 506: a novel class of topical agents for treatment of skin diseases?
Sleep Initiation and Maintenance Disorders
Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Spinal Cord Injuries
FK 506 reduces tissue damage and prevents functional deficit after spinal cord injury in the rat.
Spinal Cord Ischemia
Immunophilin ligands FK506 and cyclosporine A improve neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits.
Staphylococcal Infections
Comparison of antibacterial activity of a new cephalosporin, ceftizoxime (FK 749) with other cephalosporin antibiotics.
Starvation
In situ activities of hexokinase and fructokinase in relation to phosphorylation status of root meristem cells of Vicia faba during reactivation from sugar starvation
Starvation
In situ activities of hexokinase and fructokinase in relation to phosphorylation status of root meristem cells of Vicia faba during reactivation from sugar starvation.
Status Epilepticus
Transient diffusion-weighted imaging changes in a patient with reversible leukoencephalopathy syndrome.
Tachycardia
Coronary and systemic hemodynamic effects of the putative nitric oxide donor, FK 409, in comparison with nitroglycerin in conscious and anesthetized dogs.
Tetanus
Regulation of antigen-induced human T-lymphocyte responses by calcineurin antagonists.
Thrombosis
Vascular graft thrombosis after pancreas transplantation: comparison of the FK 506 and cyclosporine eras.
Thyroid Diseases
Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production.
Thyroiditis, Autoimmune
Suppression of autoimmune thyroid disease by FK 506: influence on thyroid-infiltrating cells, adhesion molecule expression and anti-thyroglobulin antibody production.
Tremor
Neurological complications in the European multicentre study of FK 506 and cyclosporin in primary liver transplantation.
Tremor
Neurological examinations after liver transplantation concerning patients under corticosteroid immunosuppression and either FK 506 or cyclosporin.
Tremor
Severe neurological complications following orthotopic liver transplantation in patients receiving FK 506 and prednisone.
Uveitis
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behçet's disease. Japanese FK 506 Study Group on Refractory Uveitis.
Vasculitis
Pathologic characteristics of vasculitis in renal transplant recipient dogs receiving immunosuppressive agents, FK 506, rapamycin, or RS-61443.
Vasculitis, Central Nervous System
Cerebral vasculitis during FK 506 treatment in a liver transplant patient.
Virus Diseases
Influence of hepatitis C virus infection on FK 506 blood levels in renal transplant patients.
Virus Diseases
Severe neurotoxicity after liver transplantation: association between FK 506 therapy and hepatitis C virus disease.
Whooping Cough
Mechanism of mu-opioid receptor-mediated presynaptic inhibition in the rat hippocampus in vitro.
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