2.7.1.145: deoxynucleoside kinase

This is an abbreviated version!
For detailed information about deoxynucleoside kinase, go to the full flat file.

Reaction

Synonyms

AGCK, AgdNK, BmdNK, D. melanogaster deoxynucleoside kinase, deoxyribonucleoside kinase, deoxyribonucleoside kinase , deoxyribonucleoside phosphotransferase, Dm-dNK, DmdNK, dNK, kinase (phosphorylating), deoxynucleoside, More, ms-dNK, multi-substrate deoxyribonucleoside kinase, multifunctional deoxynucleoside kinase, multispecific deoxynucleoside kinase, multisubstrate deoxyribonucleoside kinase, nucleoside triphosphate: deoxyribonucleoside 5'-phosphotransferase, pyrimidine deoxyribonucleoside kinase, white stripe leaf8, WSL8, Xen-PyK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.145 deoxynucleoside kinase

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Results	in table
28	AA Sequence
21	Application
1	CAS Registry Number
28	Cloned(Commentary)
23	Cofactor
7	Crystallization (Commentary)
1	Expression
11	General Information
1	General Stability
18	IC50 Value
47	Inhibitors
9	kcat/KM [mM/s]
22	Ki Value [mM]
140	KM Value [mM]
8	Localization
15	Metals/Ions
19	Molecular Weight [Da]
49	Natural Substrates/ Products (Substrates)
49	Organism
4	Pathway
68	PDB ID
5	pH Optimum
54	Protein Variants
14	Purification (Commentary)
7	Reaction
1	Reaction Type
47	Reference
10	Source Tissue
14	Specific Activity [micromol/min/mg]
282	Substrates and Products (Substrate)
18	Subunits
75	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
100	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 2.7.1.145 - deoxynucleoside kinase

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

314

2'-deoxy-2',2'-difluorocytidine

Drosophila melanogaster

Q9XZT6

-

702047

165 - 183.3

2'-deoxycytidine

2 entries

0.45 - 3

2'-deoxyguanosine

2 entries

9 - 65

2-amino-8-(1'-beta-D-2'-deoxyribofuranosyl)-imidazo[1,2-a]-1,3,5-triazin-4(8H)-one

2 entries

-

0.0583 - 98.3

6-amino-5-nitro-3-(1'-beta-D-2'-deoxyribofuranosyl)-2(1H)-pyridone

2 entries

-

165

2'-deoxycytidine

Drosophila melanogaster

Q9XZT6

wild type enzyme, at pH 7.6 and 37°C

762219

183.3

2'-deoxycytidine

Drosophila melanogaster

Q9XZT6

mutant enzyme Q81E, at pH 7.6 and 37°C

762219

0.45

2'-deoxyguanosine

Drosophila melanogaster

Q9XZT6

mutant enzyme Q81E, at pH 7.6 and 37°C

762219

3

2'-deoxyguanosine

Drosophila melanogaster

Q9XZT6

wild type enzyme, at pH 7.6 and 37°C

762219

9

2-amino-8-(1'-beta-D-2'-deoxyribofuranosyl)-imidazo[1,2-a]-1,3,5-triazin-4(8H)-one

Drosophila melanogaster

Q9XZT6

wild type enzyme, at pH 7.6 and 37°C

762219

-

65

2-amino-8-(1'-beta-D-2'-deoxyribofuranosyl)-imidazo[1,2-a]-1,3,5-triazin-4(8H)-one

Drosophila melanogaster

Q9XZT6

mutant enzyme Q81E, at pH 7.6 and 37°C

762219

-

0.0583

6-amino-5-nitro-3-(1'-beta-D-2'-deoxyribofuranosyl)-2(1H)-pyridone

Drosophila melanogaster

Q9XZT6

wild type enzyme, at pH 7.6 and 37°C

762219

-

98.3

6-amino-5-nitro-3-(1'-beta-D-2'-deoxyribofuranosyl)-2(1H)-pyridone

Drosophila melanogaster

Q9XZT6

mutant enzyme Q81E, at pH 7.6 and 37°C

762219

-