Crystallization (Comment) | Organism |
---|---|
truncated dNK lacking the last 20 amino acid residues in complex with gemcitabine, hanging drop vapor diffusion method, using 0.1 M MES pH 6.5, 0.2 M lithium sulfate and 26% (w/v) mPEG2000 | Drosophila melanogaster |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0207 | - |
2'-deoxy-2',2'-difluorocytidine | - |
Drosophila melanogaster |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | Q9XZT6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 2'-deoxy-2',2'-difluorocytidine | 2'-deoxy-2',2'-difluorocytidine is gemcitabine, dNK is an activator of gemcitabine | Drosophila melanogaster | ADP + difluorodeoxycytidine 5'-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
dNK | - |
Drosophila melanogaster |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
6.5 | - |
2'-deoxy-2',2'-difluorocytidine | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Drosophila melanogaster |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
314 | - |
2'-deoxy-2',2'-difluorocytidine | - |
Drosophila melanogaster |