2.7.1.145: deoxynucleoside kinase
This is an abbreviated version!
For detailed information about deoxynucleoside kinase, go to the full flat file.
Word Map on EC 2.7.1.145
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2.7.1.145
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thymidine
-
drosophila
-
deoxycytidine
-
suicide
-
deoxyguanosine
-
herpes
-
medicine
-
deoxyadenosine
-
e-5-2-bromovinyl-2'-deoxyuridine
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kinase-deficient
-
dttp
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deoxythymidine
-
dado
-
1-beta-d-arabinofuranosylthymine
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synthesis
-
agriculture
- 2.7.1.145
- thymidine
- drosophila
- deoxycytidine
-
suicide
- deoxyguanosine
-
herpes
- medicine
- deoxyadenosine
-
e-5-2-bromovinyl-2'-deoxyuridine
-
kinase-deficient
- dttp
- deoxythymidine
-
dado
- 1-beta-d-arabinofuranosylthymine
- synthesis
- agriculture
Reaction
Synonyms
AGCK, AgdNK, BmdNK, D. melanogaster deoxynucleoside kinase, deoxyribonucleoside kinase, deoxyribonucleoside kinase
ECTree
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IC50 Value
IC50 Value on EC 2.7.1.145 - deoxynucleoside kinase
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0.0277
(E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosyluracil
Drosophila melanogaster
IC50: 0.0277 mM for reaction with thymidine and 0.0158 mM for reaction with 2'-deoxycytidine
0.00257
(E)-5-(2-bromovinyl)-2'-deoxyuridine
Drosophila melanogaster
IC50: 0.00257 mM for reaction with thymidine and 0.00194 mM for reaction with 2'-deoxycytidine
0.0026
(E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-monophosphate
Drosophila melanogaster
-
IC50: 0.0026 mM, reaction with thymidine, fusion protein with glutathione S-transferase
0.0069
(E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate
Drosophila melanogaster
-
IC50: 0.0069 mM, reaction with thymidine, fusion protein with glutathione S-transferase. The inhibitor is efficiently metabolized to its 5'-mono-, 5'-di- and 5'-triphosphate derivatives in the insect cell culture and abundently incorporated into the insec
0.0163
1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil
Drosophila melanogaster
IC50: 0.0163 mM for reaction with thymidine and 0.0154 mM for reaction with 2'-deoxycytidine
0.0534
1-beta-D-arabinofuranosylcytosine
Drosophila melanogaster
IC50: 0.0534 mM for reaction with thymidine and 0.089 mM for reaction with 2'-deoxycytidine
0.0648
1-beta-D-arabinofuranosylthymidine
Drosophila melanogaster
IC50: 0.0648 mM for reaction with thymidine and 0.0348 mM for reaction with 2'-deoxycytidine
0.057
1-beta-D-arabinofuranosyluracil
Drosophila melanogaster
IC50: 0.057 mM for reaction with thymidine and 0.058 mM for reaction with 2'-deoxycytidine
0.145
2',2'-difluorodeoxycytidine
Drosophila melanogaster
IC50: 0.145 mM for reaction with thymidine and 0.102 mM for reaction with 2'-deoxycytidine
0.76
2',3'-dideoxycytidine
Drosophila melanogaster
IC50: 0.76 mM for reaction with thymidine and 0.838 mM for reaction with 2'-deoxycytidine
0.075
2',3'-dideoxythymidine
Drosophila melanogaster
IC50: 0.075 mM for reaction with thymidine and 0.0703 mM for reaction with 2'-deoxycytidine
0.74
2'-deoxy-3'-thiacytidine
Drosophila melanogaster
IC50: 0.74 mM for reaction with thymidine and 0.868 mM for reaction with 2'-deoxycytidine
0.123
2-chloro-2'-deoxyadenosine
Drosophila melanogaster
IC50: 0.123 mM for reaction with thymidine and 0.12 mM for reaction with 2'-deoxycytidine
0.0419
3'-azido-2',3'-dideoxythymidine
Drosophila melanogaster
IC50: 0.0419 mM for reaction with thymidine and 0.0296 mM for reaction with 2'-deoxycytidine
0.0258
5-fluoro-2'-deoxyuridine
Drosophila melanogaster
IC50: 0.0258 mM for reaction with thymidine and 0.02235 mM for reaction with 2'-deoxycytidine
0.012
dTTP
Drosophila melanogaster
-
IC50: 0.012 mM, reaction with thymidine, fusion protein with glutathione S-transferase
0.805
Drosophila melanogaster
IC50 for reaction with 2'-deoxycytidine is 0.805 mM