2.3.1.23: 1-acylglycerophosphocholine O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerophosphocholine O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-acyl-sn-glycero-3-phosphocholine acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-acylglycerophosphocholine acyltransferase, 1-AGP acyltransferase 8, 1-AGPAT 8, 1-AGPAT7, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, acyl-CoA:glycerophosphocholine acyltransferase, acyl-CoA:lysocardiolipin acyltransferase 1, acyl-CoA:lysophosphatidylcholine acyltransferase, acyl-CoA:lysophosphatidylethanolamine acyltransferase 2, acyl-CoA:lysophospholipid acyltransferase, acyltransferase, lysolecithin, AGPAT7, AGPAT8, Alcat1, ALE1, At1g78690, AtLPLAT2, AYTL1, AYTL2, AYTL3, CF3, CG18445, CsLPCAT, GPCAT, hPrdx6, Lclat1, LPAT, LPC acyltransferase, LPCAT, LPCAT1, LPCAT2, LPCAT3, LPCAT4, LPEAT2, LPG acyltransferase, LPGAT, LPGAT1, LPLAT, LPLAT5, lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1, LYCAT, lyso-PAF acetyltransferase, lyso-PC acyltransferase, lyso-PC acyltransferase 1, lyso-phosphatidylcholine acyltransferase 1, lysolecithin acyltransferase, lysoPC acyltransferase, lysophosphatide acyltransferase, lysophosphatidylcholine acyl transferase, lysophosphatidylcholine acyltransferase, lysophosphatidylcholine acyltransferase 1, lysophosphatidylcholine acyltransferase 3, lysophosphatidylcholine acyltransferase 4, lysophosphatidylethanolamine acyltransferase 2, lysophosphocholine acyltransferase 1, lysophosphocholine acyltransferase 2, lysophosphocholine acyltransferase 3, lysophosphocholine acyltransferase 4, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mboa-6, MBOAT protein Nes, MBOAT5, membrane-bound O-acyltransferase 5, mLPEAT2, More, mPrdx6, N-acylphosphatidylethanolamine synthase, NAPE synthase, PCAT1, PCAT2, PGAT, rPrdx6, YALI0E16797g, yeast tafazzin, Ypr140wp

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.23 1-acylglycerophosphocholine O-acyltransferase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
25	Activating Compound
741	AA Sequence
2	Application
1	CAS Registry Number
38	Cloned(Commentary)
533	Disease/ Diagnostics
7	Expression
54	General Information
2	General Stability
9	IC50 Value
110	Inhibitors
8	kcat/KM [mM/s]
6	Ki Value [mM]
65	KM Value [mM]
105	Localization
2	Metals/Ions
16	Molecular Weight [Da]
66	Natural Substrates/ Products (Substrates)
194	Organism
14	Pathway
39	pH Optimum
7	pH Range
3	Posttranslational Modification
32	Protein Variants
27	Purification (Commentary)
3	Reaction
1	Reaction Type
125	Reference
247	Source Tissue
52	Specific Activity [micromol/min/mg]
8	Storage Stability
328	Substrates and Products (Substrate)
20	Subunits
216	Synonyms
1	Systematic Name
44	Temperature Optimum [°C]
2	Temperature Range [°C]
9	Temperature Stability [°C]
2	Turnover Number [1/s]

IC50 Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

IC50 Value on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to IC50 Value Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.02

2-methoxy-5-methyl-3-tetradecanoyloxy-1,4-benzoquinone

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.166

3,4-dihydroxy-1,2-dimethoxy-5-methylbenzene

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.391

3-acetoxy-2-methoxy-5-methyl-1,4-benzoquinone

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.003

3-decanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.139

3-hexanoyloxy-2-methoxy-5-methyl-1,4-benzoquinone

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.015

CI-976

Rattus norvegicus

-

complete inhibition at 0.05 mM, IC50: 0.015 mM, inhibition of Golgi complex-associated LPAT activity by the drug CI-976 stimulates Golgi tubule formation and subsequent redistribution of resident Golgi proteins to the endoplasmic reticulum, overview

675007

0.101

dihydrofumigatin

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.109

fumigatin

Rattus norvegicus

-

at pH 6.9 and 37°C

735644

0.174

TSI-10

Homo sapiens

Q6P1A2

pH 6.0, 30°C, recombinant enzyme

756737