2.3.1.23: 1-acylglycerophosphocholine O-acyltransferase

This is an abbreviated version!
For detailed information about 1-acylglycerophosphocholine O-acyltransferase, go to the full flat file.

Reaction

Synonyms

1-acyl-sn-glycero-3-phosphocholine acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 8, 1-acylglycerophosphocholine acyltransferase, 1-AGP acyltransferase 8, 1-AGPAT 8, 1-AGPAT7, acetyl-CoA:1-O-alkyl-sn-glycero-3-phosphocholine acetyltransferase, acyl coenzyme A-monoacylphosphatidylcholine acyltransferase, acyl-CoA:1-acyl-glycero-3-phosphocholine transacylase, acyl-CoA:glycerophosphocholine acyltransferase, acyl-CoA:lysocardiolipin acyltransferase 1, acyl-CoA:lysophosphatidylcholine acyltransferase, acyl-CoA:lysophosphatidylethanolamine acyltransferase 2, acyl-CoA:lysophospholipid acyltransferase, acyltransferase, lysolecithin, AGPAT7, AGPAT8, Alcat1, ALE1, At1g78690, AtLPLAT2, AYTL1, AYTL2, AYTL3, CF3, CG18445, CsLPCAT, GPCAT, hPrdx6, Lclat1, LPAT, LPC acyltransferase, LPCAT, LPCAT1, LPCAT2, LPCAT3, LPCAT4, LPEAT2, LPG acyltransferase, LPGAT, LPGAT1, LPLAT, LPLAT5, lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1, LYCAT, lyso-PAF acetyltransferase, lyso-PC acyltransferase, lyso-PC acyltransferase 1, lyso-phosphatidylcholine acyltransferase 1, lysolecithin acyltransferase, lysoPC acyltransferase, lysophosphatide acyltransferase, lysophosphatidylcholine acyl transferase, lysophosphatidylcholine acyltransferase, lysophosphatidylcholine acyltransferase 1, lysophosphatidylcholine acyltransferase 3, lysophosphatidylcholine acyltransferase 4, lysophosphatidylethanolamine acyltransferase 2, lysophosphocholine acyltransferase 1, lysophosphocholine acyltransferase 2, lysophosphocholine acyltransferase 3, lysophosphocholine acyltransferase 4, lysophospholipid acyltransferase, lysophospholipid:acyl-CoA acyltransferase, mboa-6, MBOAT protein Nes, MBOAT5, membrane-bound O-acyltransferase 5, mLPEAT2, More, mPrdx6, N-acylphosphatidylethanolamine synthase, NAPE synthase, PCAT1, PCAT2, PGAT, rPrdx6, YALI0E16797g, yeast tafazzin, Ypr140wp

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.1 Transferring groups other than aminoacyl groups

                2.3.1.23 1-acylglycerophosphocholine O-acyltransferase

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Results	in table
25	Activating Compound
741	AA Sequence
2	Application
1	CAS Registry Number
38	Cloned(Commentary)
533	Disease/ Diagnostics
7	Expression
54	General Information
2	General Stability
9	IC50 Value
110	Inhibitors
8	kcat/KM [mM/s]
6	Ki Value [mM]
65	KM Value [mM]
105	Localization
2	Metals/Ions
16	Molecular Weight [Da]
66	Natural Substrates/ Products (Substrates)
194	Organism
14	Pathway
39	pH Optimum
7	pH Range
3	Posttranslational Modification
32	Protein Variants
27	Purification (Commentary)
3	Reaction
1	Reaction Type
125	Reference
247	Source Tissue
52	Specific Activity [micromol/min/mg]
8	Storage Stability
328	Substrates and Products (Substrate)
20	Subunits
216	Synonyms
1	Systematic Name
44	Temperature Optimum [°C]
2	Temperature Range [°C]
9	Temperature Stability [°C]
2	Turnover Number [1/s]

pH Range

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pH Range on EC 2.3.1.23 - 1-acylglycerophosphocholine O-acyltransferase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5 - 10

Cavia porcellus

-

approx. half-maximal activity at pH 5.0 and 10.0

486629

5.5 - 8.5

Rattus norvegicus

-

approx. half-maximal activity at pH 5.5 and 8.5

486633

6 - 10

Rattus norvegicus

-

pH 6.0: about 55% of maximal activity, pH 10.0: about 80% of maximal activity, Golgi-associated enzyme

657761

6 - 12

Camelina sativa

-

activity range, 64% of maximal activity at pH 11.0, 34% at pH 12.0, and 10% at pH 6.0

758095

6 - 9

2 entries

6.5 - 8

Brassica napus

-

pH 6.5: about 80% of maximal activity, pH 8.0: about 70% of maximal activity

659833

6 - 9

Bos taurus

-

almost no activity at pH 6.0 and pH 9.0

486650

6 - 9

Rattus norvegicus

-

approx. half-maximal activity at pH 6.0 and 9.6

486637