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1.4.3.22: diamine oxidase

This is an abbreviated version!
For detailed information about diamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.22

Reaction

histamine
+
H2O
+
O2
=
(imidazol-4-yl)acetaldehyde
+
NH3
+
H2O2

Synonyms

ABP1, AGAO, Amiloride-binding protein, Amine oxidase, BSAO, Copper amine oxidase, DAO, DAO-1, Diamine oxidase, EC 1.4.3.6, ELAO, GPAO, hDAO, histaminase, histamine dehydrogenase, histamine oxidase, LCAO, LSAO, methylputrescine oxidase, More, MPO, N-methylputrescine oxidase, pea seedling amine oxidase, PKAO, PPLO, PSAO, pWGH15, rhDAO, vDAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.22 diamine oxidase

Temperature Stability

Temperature Stability on EC 1.4.3.22 - diamine oxidase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0 - 60
-
10 min, pH 7.0, stable
100
-
10 min, complete loss of activity
30 - 60
-
the enzyme retains its activity after being incubated at 30°C for 30 min, the enzyme is rapidly deactivated above 45°C and reaches almost zero activity at 60°C
40
-
stable below, unstable above 50°C
69
-
Tm-value of aminoguanidine-inhibited enzyme
80
-
15 min, complete loss of activity
additional information
-
deglycosylation has no effect on the thermal stability of the enzyme. Aminoguanidine raises the stability of the protein