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1.4.3.22: diamine oxidase

This is an abbreviated version!
For detailed information about diamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.22

Reaction

histamine
+
H2O
+
O2
=
(imidazol-4-yl)acetaldehyde
+
NH3
+
H2O2

Synonyms

ABP1, AGAO, Amiloride-binding protein, Amine oxidase, BSAO, Copper amine oxidase, DAO, DAO-1, Diamine oxidase, EC 1.4.3.6, ELAO, GPAO, hDAO, histaminase, histamine dehydrogenase, histamine oxidase, LCAO, LSAO, methylputrescine oxidase, More, MPO, N-methylputrescine oxidase, pea seedling amine oxidase, PKAO, PPLO, PSAO, pWGH15, rhDAO, vDAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.22 diamine oxidase

KM Value

KM Value on EC 1.4.3.22 - diamine oxidase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.1
(E)-1,4-diamino-2-butene
0.13 - 17
1,3-diaminopropane
0.36
1,4-diamino-2-butene
-
-
0.2 - 2.85
1,4-diaminobutane
0.14
1,4-methylhistamine
-
0.2
1,5-diamino-3-oxapentane
-
-
0.47
1,5-Diaminopentane
-
-
0.11 - 0.15
1,6-diaminohexane
0.00036
1,8-diaminooctane
-
pH 7.2, 37°C
2.5
1-aminobutane
-
pH 7.2, 37°C
0.0087
1-aminononane
-
pH 7.2, 37°C
0.0034
1-Methylhistamine
-
pH 7.2, 37°C
0.051 - 0.16
2-aminoethylpyridine
0.005 - 0.031
2-aminomethylpyridine
0.67
2-hydroxyputrescine
0.12
2-Phenylethylamine
-
0.21 - 0.58
3-aminomethylpyridine
0.09
3-hydroxycadaverine
0.1 - 0.48
4-aminomethylpyridine
0.004
4-aminomethylpyridine dihydrochloride
-
9.71
acetylputrescine
-
-
0.017 - 0.5
agmatine
0.6
aminobutane
-
0.15 - 0.2
aminohexane
0.35
aminopentane
-
1.6
Aminopropane
-
0.12 - 2.2
benzaldehyde
0.1 - 4.1
benzylamine
0.877 - 5
Butylamine
0.0146 - 8.1
cadaverine
0.1
cystamine
66
ethylamine
-
at pH 7.4
0.63 - 66
ethylenediamine
0.0028 - 2.3
histamine
2.8
L-Lysine methyl ester
-
pH 7.2, 37°C
6.5
lysine methylester
-
at pH 7.4
0.075 - 0.158
Methylhistamine
0.097
N(tau)-methylhistamine
-
-
3.28
N-acetylcadaverine
-
-
-
0.19 - 1.22
N-methylputrescine
0.625
N1-acetylspermidine
-
-
0.15 - 0.33
N6-(4-amino-trans-but-2-enyl)adenine
0.25 - 0.77
N6-(4-aminobutyl)adenine
0.64
N8-Acetylspermidine
-
pH 7.2, 37°C
1.05
norepinephrine
-
0.00037 - 0.046
O2
0.36
octopamine
-
0.11
p-dimethylaminomethylbenzylamine
-
pH 7.2, 37°C
0.0015 - 1.4
Phenylethylamine
3.4 - 6.6
Propylamine
0.01 - 7
putrescine
0.29
serotonin
-
0.022 - 9.52
spermidine
0.02 - 5.71
spermine
0.1
tryptamine
-
0.12 - 3.1
tyramine
additional information
additional information
-
the kinetic properties of the MPO1 enzyme may play an important role in determining the pyridine alkaloid profiles observed in tobacco roots
-