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7.1.2.2: H+-transporting two-sector ATPase

This is an abbreviated version!
For detailed information about H+-transporting two-sector ATPase, go to the full flat file.

Word Map on EC 7.1.2.2

Reaction

ATP
+
H2O
 + 4 H+[side 1] =
ADP
 +
phosphate
 + 4 H+[side 2]

Synonyms

15 kDa mediatophore protein, 32 kDa accessory protein, 59 kDa membrane-associated GTP-binding protein, A-ATP synthase, A-ATPase, A1A0-ATP synthase, A1AO ATP synthase, A6L, ApNa+-ATPase, ATP synthase, ATP synthase F1, ATP synthase proteolipid P1, ATP synthase proteolipid P2, ATP synthase proteolipid P3, ATP5alpha1, ATPase, ATPaseTb2, atpB, AtpZ, bacterial Ca2+/Mg2+ ATPase, BN59, C7-1 protein, cf1, CF1-ATPase, CGI-11, chloroplast ATP synthase, chloroplast ATPase, chlorpoplast ATP synthase, complex V, coupling factor CF1, coupling factors (F0,F1 and CF1), Dicyclohexylcarbodiimide-binding protein, Ductin, DVA41, EC 3.6.1.34, EC 3.6.3.14, ECF1, Ecto-F1Fo ATP synthase/F1 ATPase, ectopic FoF1 ATP synthase, F-type proton-translocating ATPase, F0F1 ATP synthase, F0F1-ATP synthase, F0F1-ATP synthase alpha, F0F1-ATPase, F0F1ATP synthase, F1, F1 ATPase, F1-ATP synthase, F1-ATPase, F1-ATPase beta subunit, F1-F0 ATP synthase, F1F0 ATP synthase, F1F0 ATPase, F1F0-ATP synthase, F1F0-ATPase, F1F0H+-ATPase, F1Fo, F1Fo ATP synthase, F1FO ATPase, F1FO-ATP synthase, F1FO-ATPase, FoF1, FoF1 ATP synthase, FoF1 ATPase, FoF1-ATP synthase, FoF1-ATPase, FoF1-ATPase/synthase, FoF1H+-ATPase/synthase, Fo·F1-H+-ATPase (synthase), H(+)-transporting ATP synthase, H+ FoF1-ATP synthase, H+-ATP synthase, H+-ATPase, H+-coupled ATP synthase, H+-translocating ATPase, H+-transporting ATP synthase, H+-transporting ATPase, H+-V-ATPase, HATPL, HO57, Invasion protein invC, Isoform HO68, Isoform VA68, Lipid-binding protein, M40, matpase, membrane-associated ATPase, mitochondrial ATPase, mitochondrial F(1)-ATPase, mitochondrial F0F1-ATP synthase, mitochondrial F1F0 ATP hydrolase, mitochondrial F1Fo-ATP synthase, mitochondrial FOF1 ATP synthase, mitochondrial H+-ATP synthase, More, My032 protein, Na+-dependent F1F0-ATP synthase, Oligomycin sensitivity conferral protein, OSCP, P31, P39, photosynthetic F1-ATPase, Physophilin, PKIWI505, plasma membrane V-ATPase, plasma membrane vacuolar H+-ATPase, Protein bellwether, proton translocating chloroplast ATP synthase, proton-translocating ATPase, rotary FOF1-ATPase, rotary molecular motor, Spa47, Stv1p, Sul-ATPase, Sul-ATPase alpha, Sul-ATPase beta, SUL-ATPase epsilon, Sul-ATPase gamma, T3SS ATPase, Tbeta, TF1, TF1-ATPase, TFoF1, tonoplast H+-ATPase, type III secretion-associated ATPase, uncB, UV-inducible PU4 protein, V-ATPase, V-ATPase 28 kDa accessory protein, V-ATPase 40 kDa accessory protein, V-ATPase 41 KDa accessory protein, V-ATPase 9.2 kDa membrane accessory protein, V-ATPase S1 accessory protein, V-pump, V-type ATPase/synthase, V-type H+-ATPase, V1VO ATPase, vacuolar (H+)-ATPase, vacuolar ATPase, vacuolar H(+)-ATPase, vacuolar H+-ATPase, vacuolar H+-pumping ATPase, vacuolar H+-translocating ATPase, vacuolar H+-transporting adenosine triphosphatase, vacuolar proton-translocating ATPase, vacuolar-type H+-ATPase, vacuolar-type H+-translocating ATPase, vacuolar-type proton pumping ATPase, vacuolar-type, proton-translocating ATPase enzyme complex, VEG100, VEG31, Vegetative protein 100, Vegetative protein 31, VHA, VHA-A, VHA16K, VMA8, Vma8p, Vph1p, YOPS secretion ATPase

ECTree

     7 Translocases
         7.1 Catalysing the translocation of hydrons
             7.1.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.1.2.2 H+-transporting two-sector ATPase

Activating Compound

Activating Compound on EC 7.1.2.2 - H+-transporting two-sector ATPase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4-dinitrophenol
abscisic acid
-
plant hormone abscisic acid slightly induces the enzyme expression and highly increases the enzyme's H+-translocation activity
apoA-I
-
the enzyme binds apoA-I which activates the ATPase activity. The antiapoptotic and proliferative effects of apoA-I on HUVECs are totally blocked by the F1-ATPase ligands IF1-H49K, angiostatin and anti-F1-ATPase antibody, independently of the scavenger receptor SR-BI and ABCA1
-
cyclosporin A
-
cyclosporin A stimulates both ATP hydrolysis and synthesis, and displaces cyclophilin D from MgATP-submitochondrial particles
gramicidin D
-
-
lauryl dimethylamine-N-oxide
Thermosynechococcus vestitus
-
-
Lauryldimethylamine oxide
light
-
promotes ATP hydrolysis
-
N,N'-dicyclohexylcarbodiimide
-
0.1 mM increases ATPase activity by 20%
NaHCO3
-
stimulator of Mg2+-ATPase activity of CF1. The rate of ATP hydrolysis increases significantly, when 1 mM NaHCO3 is added to the medium (pH 7.8)
soybean phospholipid
-
-
-
sulfate
-
ATP hydrolysis-driven H+ translocation is stimulated by sulfate, but sulfate is a partial inhibitor at low and a nonessential activator at high ATP concentrations of the ATPase activity of F1
sulfite
Trypsin
-
elicits higher rates of ATPase activity, Mg2+-ATPase activity of trypsinized thylakoids is only partially inhibited by the uncouplers
-
additional information
-