7.1.2.2: H+-transporting two-sector ATPase

This is an abbreviated version!
For detailed information about H+-transporting two-sector ATPase, go to the full flat file.

Reaction

Synonyms

15 kDa mediatophore protein, 32 kDa accessory protein, 59 kDa membrane-associated GTP-binding protein, A-ATP synthase, A-ATPase, A1A0-ATP synthase, A1AO ATP synthase, A6L, ApNa+-ATPase, ATP synthase, ATP synthase F1, ATP synthase proteolipid P1, ATP synthase proteolipid P2, ATP synthase proteolipid P3, ATP5alpha1, ATPase, ATPaseTb2, atpB, AtpZ, bacterial Ca2+/Mg2+ ATPase, BN59, C7-1 protein, cf1, CF1-ATPase, CGI-11, chloroplast ATP synthase, chloroplast ATPase, chlorpoplast ATP synthase, complex V, coupling factor CF1, coupling factors (F0,F1 and CF1), Dicyclohexylcarbodiimide-binding protein, Ductin, DVA41, EC 3.6.1.34, EC 3.6.3.14, ECF1, Ecto-F1Fo ATP synthase/F1 ATPase, ectopic FoF1 ATP synthase, F-type proton-translocating ATPase, F0F1 ATP synthase, F0F1-ATP synthase, F0F1-ATP synthase alpha, F0F1-ATPase, F0F1ATP synthase, F1, F1 ATPase, F1-ATP synthase, F1-ATPase, F1-ATPase beta subunit, F1-F0 ATP synthase, F1F0 ATP synthase, F1F0 ATPase, F1F0-ATP synthase, F1F0-ATPase, F1F0H+-ATPase, F1Fo, F1Fo ATP synthase, F1FO ATPase, F1FO-ATP synthase, F1FO-ATPase, FoF1, FoF1 ATP synthase, FoF1 ATPase, FoF1-ATP synthase, FoF1-ATPase, FoF1-ATPase/synthase, FoF1H+-ATPase/synthase, Fo�F1-H+-ATPase (synthase), H(+)-transporting ATP synthase, H+ FoF1-ATP synthase, H+-ATP synthase, H+-ATPase, H+-coupled ATP synthase, H+-translocating ATPase, H+-transporting ATP synthase, H+-transporting ATPase, H+-V-ATPase, HATPL, HO57, Invasion protein invC, Isoform HO68, Isoform VA68, Lipid-binding protein, M40, matpase, membrane-associated ATPase, mitochondrial ATPase, mitochondrial F(1)-ATPase, mitochondrial F0F1-ATP synthase, mitochondrial F1F0 ATP hydrolase, mitochondrial F1Fo-ATP synthase, mitochondrial FOF1 ATP synthase, mitochondrial H+-ATP synthase, More, My032 protein, Na+-dependent F1F0-ATP synthase, Oligomycin sensitivity conferral protein, OSCP, P31, P39, photosynthetic F1-ATPase, Physophilin, PKIWI505, plasma membrane V-ATPase, plasma membrane vacuolar H+-ATPase, Protein bellwether, proton translocating chloroplast ATP synthase, proton-translocating ATPase, rotary FOF1-ATPase, rotary molecular motor, Spa47, Stv1p, Sul-ATPase, Sul-ATPase alpha, Sul-ATPase beta, SUL-ATPase epsilon, Sul-ATPase gamma, T3SS ATPase, Tbeta, TF1, TF1-ATPase, TFoF1, tonoplast H+-ATPase, type III secretion-associated ATPase, uncB, UV-inducible PU4 protein, V-ATPase, V-ATPase 28 kDa accessory protein, V-ATPase 40 kDa accessory protein, V-ATPase 41 KDa accessory protein, V-ATPase 9.2 kDa membrane accessory protein, V-ATPase S1 accessory protein, V-pump, V-type ATPase/synthase, V-type H+-ATPase, V1VO ATPase, vacuolar (H+)-ATPase, vacuolar ATPase, vacuolar H(+)-ATPase, vacuolar H+-ATPase, vacuolar H+-pumping ATPase, vacuolar H+-translocating ATPase, vacuolar H+-transporting adenosine triphosphatase, vacuolar proton-translocating ATPase, vacuolar-type H+-ATPase, vacuolar-type H+-translocating ATPase, vacuolar-type proton pumping ATPase, vacuolar-type, proton-translocating ATPase enzyme complex, VEG100, VEG31, Vegetative protein 100, Vegetative protein 31, VHA, VHA-A, VHA16K, VMA8, Vma8p, Vph1p, YOPS secretion ATPase

ECTree

     7 Translocases

         7.1 Catalysing the translocation of hydrons

             7.1.2 Linked to the hydrolysis of a nucleoside triphosphate

                7.1.2.2 H+-transporting two-sector ATPase

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Results	in table
24	Activating Compound
137971	AA Sequence
18	Application
1	CAS Registry Number
63	Cloned(Commentary)
12	Cofactor
22	Crystallization (Commentary)
4035	Disease/ Diagnostics
6	Expression
118	General Information
1	General Stability
4	IC50 Value
253	Inhibitors
6	kcat/KM [mM/s]
4	Ki Value [mM]
50	KM Value [mM]
267	Localization
160	Metals/Ions
107	Molecular Weight [Da]
202	Natural Substrates/ Products (Substrates)
616	Organism
6	Pathway
919	PDB ID
37	pH Optimum
6	pH Range
1	pI Value
2	Posttranslational Modification
233	Protein Variants
60	Purification (Commentary)
51	Reaction
2	Reaction Type
358	Reference
7	Renatured (Commentary)
90	Source Tissue
19	Specific Activity [micromol/min/mg]
6	Storage Stability
499	Substrates and Products (Substrate)
144	Subunits
461	Synonyms
1	Systematic Name
25	Temperature Optimum [°C]
4	Temperature Range [°C]
15	Temperature Stability [°C]
16	Turnover Number [1/s]

pH Range

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pH Range on EC 7.1.2.2 - H+-transporting two-sector ATPase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

10

Haloferax volcanii

-

ATP synthesis in washed membranes of Haloferax volcanii, 75% of the optimal activity

727822

5.5 - 7.5

Escherichia coli

-

at pH 7.5 H+ efflux is stimulated in fhlA mutant, with defective transcriptional activator of Hyd-3 or Hyd-4, and lowered in hyaB or hybC mutants, with defective Hyd-1 or Hyd-2. At pH 5.5 H+ efflux in wild-type cells is lowered compared with that at pH 7.5, but is increased in fhlA mutant and absent in hyaB/hybC mutant, overview

711528

6.5 - 8

Bos taurus

-

-

696051

7 - 9

[Clostridium] paradoxum

Q0ZS18, Q0ZS19, Q0ZS20, Q0ZS21, Q0ZS22, Q0ZS23, Q0ZS24, Q0ZS25, Q0ZS26

enzyme retains ca. 20% of its maximum activity at below pH 7.0

669124

7 - 9.5

Acidithiobacillus ferrooxidans

-

ATPase activity decreases markedly above or below this range

672662

additional information

Escherichia coli

-

pH-dependence of unisite and multisite catalysis

210246