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4.3.1.19: threonine ammonia-lyase

This is an abbreviated version!
For detailed information about threonine ammonia-lyase, go to the full flat file.

Word Map on EC 4.3.1.19

Reaction

2-aminobut-2-enoate
=
2-iminobutanoate

Synonyms

BsBTD1, CgBTD1, CgCTD, EC 4.2.1.16, EcBTD2, EcCTD, FgIlv1, GSU0486, ilvA, L-TD, L-TDH, L-threonine deaminase, L-threonine dehydratase, MSMEG3183, OMR1, PpBTD2, pTD2, SaBTD1, SaCTD, SgBTD1, SlTD1, SlTD2, sp0454, TD, TD1, TD2, tdcB, TDH, TH, Thr ammonia-lyase, threonine ammonia-lyase, Threonine deaminase, threonine deaminase/dehydratase, threonine dehydrase, threonine dehydratase, threonine dehydratase/deaminase

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.19 threonine ammonia-lyase

Temperature Stability

Temperature Stability on EC 4.3.1.19 - threonine ammonia-lyase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0
-
10 h, 81% loss of activity in presence of 0.05 mM Ile, stable in presence of 1 mM Ile
27
-
10 h, 27% loss of activity in presence of 0.05 mM Ile, stable in presence of 1 mM Ile
37
-
10 min, 16% loss of activity of dehydratase I and 36% loss of activity of dehydratase II, loss of activity of dehydratase I is prevented by 1 mM Ile, but that of dehydratase II is not
39
15 min, 50% loss of activity, wild-type enzyme
41
15 min, 50% loss of activity, mutant enzyme A14T
41.2
15 min, 50% loss of activity, mutant enzyme R449C
44.8
15 min, 50% loss of activity, mutant enzyme F510L
45
-
15 min, complete loss of activity in absence of phosphate, 94% loss of activity in presence of 50 mM phosphate, 49% loss of activity in presence of 250 mM phosphate
46.2
15 min, 50% loss of activity, mutant enzyme G323D
47.1
15 min, 50% loss of activity, mutant enzyme G323D/T344A
52.4
15 min, 50% loss of activity, mutant enzyme G323D/F510L/R449C
52.5
15 min, 50% loss of activity, mutant enzyme G323D/F510L
70
-
1 h, 15% loss of activity
90
-
rapid inactivation