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Literature summary for 4.3.1.19 extracted from

  • Bode, R.; Birnbaum, D.
    Threonine dehydratase activity from several yeast species is activated and affected by phosphate (1986), FEMS Microbiol. Lett., 37, 189-192.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
phosphate increases activity Cyberlindnera jadinii
phosphate increases activity Saccharomyces cerevisiae
phosphate increases activity Yarrowia lipolytica
phosphate increases activity Ogataea angusta
phosphate increases activity Sporidiobolus salmonicolor
phosphate increases activity Meyerozyma guilliermondii
phosphate increases activity Rhodotorula toruloides
phosphate increases activity Ogataea henricii
phosphate increases activity Wickerhamomyces anomalus
phosphate increases activity Candida maltosa
phosphate increases activity Solicoccozyma terrea
phosphate increases activity Brettanomyces anomalus
phosphate increases activity Ogataea pini
phosphate increases activity Trigonopsis variabilis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5
-
L-Thr in absence of phosphate Candida maltosa
3
-
L-Thr in presence of 50 mM phosphate Candida maltosa
4
-
L-Thr in presence of 250 mM phosphate Candida maltosa

Organism

Organism UniProt Comment Textmining
Brettanomyces anomalus
-
-
-
Candida maltosa
-
-
-
Cyberlindnera jadinii
-
-
-
Meyerozyma guilliermondii
-
-
-
Ogataea angusta
-
-
-
Ogataea henricii
-
-
-
Ogataea pini
-
-
-
Rhodotorula toruloides
-
-
-
Saccharomyces cerevisiae
-
-
-
Solicoccozyma terrea
-
-
-
Sporidiobolus salmonicolor
-
-
-
Trigonopsis variabilis
-
-
-
Wickerhamomyces anomalus
-
-
-
Yarrowia lipolytica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-threonine
-
Cyberlindnera jadinii 2-oxobutanoate + NH3
-
?
L-threonine
-
Saccharomyces cerevisiae 2-oxobutanoate + NH3
-
?
L-threonine
-
Yarrowia lipolytica 2-oxobutanoate + NH3
-
?
L-threonine
-
Ogataea angusta 2-oxobutanoate + NH3
-
?
L-threonine
-
Sporidiobolus salmonicolor 2-oxobutanoate + NH3
-
?
L-threonine
-
Meyerozyma guilliermondii 2-oxobutanoate + NH3
-
?
L-threonine
-
Rhodotorula toruloides 2-oxobutanoate + NH3
-
?
L-threonine
-
Ogataea henricii 2-oxobutanoate + NH3
-
?
L-threonine
-
Wickerhamomyces anomalus 2-oxobutanoate + NH3
-
?
L-threonine
-
Candida maltosa 2-oxobutanoate + NH3
-
?
L-threonine
-
Solicoccozyma terrea 2-oxobutanoate + NH3
-
?
L-threonine
-
Brettanomyces anomalus 2-oxobutanoate + NH3
-
?
L-threonine
-
Ogataea pini 2-oxobutanoate + NH3
-
?
L-threonine
-
Trigonopsis variabilis 2-oxobutanoate + NH3
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35
-
in absence of phosphate Candida maltosa
37
-
in presence of 50 mM phosphate Candida maltosa
44
-
in presence of 250 mM phosphate Candida maltosa

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
45
-
15 min, complete loss of activity in absence of phosphate, 94% loss of activity in presence of 50 mM phosphate, 49% loss of activity in presence of 250 mM phosphate Candida maltosa