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4.3.1.19: threonine ammonia-lyase

This is an abbreviated version!
For detailed information about threonine ammonia-lyase, go to the full flat file.

Word Map on EC 4.3.1.19

Reaction

2-aminobut-2-enoate
=
2-iminobutanoate

Synonyms

BsBTD1, CgBTD1, CgCTD, EC 4.2.1.16, EcBTD2, EcCTD, FgIlv1, GSU0486, ilvA, L-TD, L-TDH, L-threonine deaminase, L-threonine dehydratase, MSMEG3183, OMR1, PpBTD2, pTD2, SaBTD1, SaCTD, SgBTD1, SlTD1, SlTD2, sp0454, TD, TD1, TD2, tdcB, TDH, TH, Thr ammonia-lyase, threonine ammonia-lyase, Threonine deaminase, threonine deaminase/dehydratase, threonine dehydrase, threonine dehydratase, threonine dehydratase/deaminase

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.19 threonine ammonia-lyase

pH Range

pH Range on EC 4.3.1.19 - threonine ammonia-lyase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
6.8 - 8.9
pH has no significant effect on activity
7 - 8
-
65% of maximal activity at pH 7 and at pH 8
7.5 - 9.5
8.1 - 9.6
-
50% of maximal activity at pH 8.1 and 9.6
8.5 - 11
-
pH 8.5: about 30% of maximal activity, pH 11.0: about 70% of maximal activity, with L-Thr as substrate
additional information
the enzyme is highly active in an alkaline pH range, little or no activity is observed at pH values below 6.0