1.5.8.4: dimethylglycine dehydrogenase
This is an abbreviated version!
For detailed information about dimethylglycine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.8.4
-
1.5.8.4
-
sarcosine
-
fad
-
flavinylated
-
folate-binding
-
wagner
-
medicine
-
diagnostics
- 1.5.8.4
- sarcosine
- fad
-
flavinylated
-
folate-binding
-
wagner
- medicine
- diagnostics
Reaction
Synonyms
Csal_0990, DdhC, DMGDH, EC 1.5.99.2, Me2GlyDH, mMe2GlyDH, N,N-dimethylglycine oxidase, pMe2GlyDH
ECTree
Advanced search results
Natural Substrates Products
Natural Substrates Products on EC 1.5.8.4 - dimethylglycine dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
5,10-methenyltetrahydrofolate + FADH2
5,10-methylene tetrahydrofolate + FAD
-
-
-
-
?
N,N-dimethylglycine + 5,6,7,8-tetrahydrofolate + electron-transfer flavoprotein
sarcosine + 5,10-methylenetetrahydrofolate + reduced electron-transfer flavoprotein
the enzyme takes part in choline degradation, one-carbon metabolism and electron transfer to the respiratory chain
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
N,N-dimethylglycine + electron-transfer flavoprotein + H2O
sarcosine + formaldehyde + reduced electron-transfer flavoprotein
-
-
-
?
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
during the reaction tightly bound tetrahydropteroylpentaglutamate is converted to 5,10-methylene tetrahydropteroylpentaglutamate
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
reaction of the choline degradation pathway
-
?
N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor
sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
-
tetrahydropteroylpentaglutamate is used in vivo as an acceptor of the one-carbon group generated during the reaction
-
?