1.5.8.4: dimethylglycine dehydrogenase
This is an abbreviated version!
For detailed information about dimethylglycine dehydrogenase, go to the full flat file.
Word Map on EC 1.5.8.4
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1.5.8.4
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sarcosine
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fad
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flavinylated
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folate-binding
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wagner
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medicine
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diagnostics
- 1.5.8.4
- sarcosine
- fad
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flavinylated
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folate-binding
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wagner
- medicine
- diagnostics
Reaction
Synonyms
Csal_0990, DdhC, DMGDH, EC 1.5.99.2, Me2GlyDH, mMe2GlyDH, N,N-dimethylglycine oxidase, pMe2GlyDH
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Inhibitors
Inhibitors on EC 1.5.8.4 - dimethylglycine dehydrogenase
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Na+, K+, Ca2+, Zn2+, Mn2+, Mg2+, Fe2+, and Co2+ display no or slightly inhibitory effects at 2 mM
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additional information
the expressions of 23 genes, including the dimethylglycine dehydrogenase precursor pMe2GlyDH, are significantly down-regulated in the hearts of cardio-specific caspase recruitment domain transgenic mice. Caspase recruitment domain ARC may protect cardiomyocytes from hypoxic cell death by regulating its downstream, dimethylglycine dehydrogenase and developmentally regulated RNA-binding protein Drbp1
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additional information
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the expressions of 23 genes, including the dimethylglycine dehydrogenase precursor pMe2GlyDH, are significantly down-regulated in the hearts of cardio-specific caspase recruitment domain transgenic mice. Caspase recruitment domain ARC may protect cardiomyocytes from hypoxic cell death by regulating its downstream, dimethylglycine dehydrogenase and developmentally regulated RNA-binding protein Drbp1
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