25/26-hydroxycholesterol 7alpha-hydroxylase

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For detailed information about 25/26-hydroxycholesterol 7alpha-hydroxylase, go to the full flat file.

Word Map on EC


[reduced NADPH-hemoprotein reductase]
[oxidized NADPH-hemoprotein reductase]


25-hydroxycholesterol 7alpha-hydroxylase, 25-hydroxycholesterol 7alpha-monooxygenase, 25-hydroxycholesterol-7alpha-hydroxylase, cholesterol 25-hydroxylase, Cyp39a1, CYP7B, CYP7B1, CYP7B1 oxysterol 7alpha-hydroxylase, CYPB1, cytochome P450 7B1, cytochrome P-450 oxysterol 7-alpha-hydroxylase, oxysterol 7 alpha-hydroxylase, oxysterol 7alpha-hydroxylase, oxysterol-7alpha-hydroxylase, Steroid hydroxylase


     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
       25/26-hydroxycholesterol 7alpha-hydroxylase


Cloned on EC - 25/26-hydroxycholesterol 7alpha-hydroxylase

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14 deletion mutants of the regulatory sequences of CYP7B1/Luc reporter gene are constructed for transfection assays. The constructs are transiently transfected into HepG2, NT1088, and HEK 293 cells
CYP7B1 genotyping and screening for CYP7B1 mutations in a large cohort of 105 Italian HSP index patients, including 50 patients with a complicated phenotype and 55 with a pure form, overall mutation frequencies of CYP7B1, overview
expression in 293/T cells
from pCMV6 vector overexpressed in HEK-293 cells