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EC 3.4.24.45 Details
EC number
3.4.24.45
Accepted name
atrolysin F
Reaction
Cleavage of Val2┼Asn, Gln4┼His, Leu6┼Cys, His10┼Leu, Ala14┼Leu and Tyr16┼Leu bonds in insulin B chain
Other name(s)
Crotalus atrox metalloendopeptidase,
hemorrhagic toxin f,
Crotalus atrox metalloendopeptidase f
CAS registry number
172306-52-4
Comment
A 64 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests the γ chain of fibrinogen. Immunologically distinct from EC 3.4.24.1, atrolysin A.
History
created 1992
EC Tree
3.4.24.2 created 1972, deleted 1992
3.4.24.4 created 1972 [EC 3.4.99.13 and EC 3.4.99.22 both created 1972, incorporated 1978], deleted 1992
3.4.24.5 created 1978, deleted 1989
3.4.24.8 created 1978, deleted 1992
3.4.24.9 created 1978, deleted 1992
3.4.24.10 created 1972 as EC 3.4.99.12, transferred 1978 to EC 3.4.24.10, deleted 1992