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EC 3.4.24.38 Details
EC number
3.4.24.38
Accepted name
gametolysin
Reaction
Cleavage of the proline- and hydroxyproline-rich proteins of the Chlamydomonas cell wall; also cleaves azocasein, gelatin and Leu-Trp-Met┼Arg-Phe-Ala
Other name(s)
autolysin, Chlamydomonas cell wall degrading protease, lysin, Chlamydomonas reinhardtii metalloproteinase, gamete lytic enzyme, gamete autolysin
CAS registry number
97089-74-2
Comment
A glycoprotein found in the periplasmic space of Chlamydomonas reinhardtii gametes in a 62 kDa inactive form; decreased to 60 kDa upon activation. A zinc enzyme, inhibited by phosphoramidon, but also thiol activated. Type example of peptidase family M11
History
created 1992, modified 2000
EC Tree
3.4.24.2 created 1972, deleted 1992
3.4.24.4 created 1972 [EC 3.4.99.13 and EC 3.4.99.22 both created 1972, incorporated 1978], deleted 1992
3.4.24.5 created 1978, deleted 1989
3.4.24.8 created 1978, deleted 1992
3.4.24.9 created 1978, deleted 1992
3.4.24.10 created 1972 as EC 3.4.99.12, transferred 1978 to EC 3.4.24.10, deleted 1992