Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.2.22: xanthine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about xanthine phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.22

Reaction

XMP
+
diphosphate
=
5-phospho-alpha-D-ribose 1-diphosphate
 +
xanthine

Synonyms

5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase, EcXGPRT, HGXPRT, hypoxanthine-guanine-(xanthine) phosphoribosyltransferase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, More, Pf HGXPRT, phosphoribosyltransferase, xanthine, ttha0535, TtXPRT, Xan phosphoribosyltransferase, xanthine phosphoribosyltransferase, xanthine PRT, xanthine-guanine PRT, xanthosine 5'-phosphate pyrophosphorylase, xanthylate pyrophosphorylase, xanthylic pyrophosphorylase, XGPRT , XMP pyrophosphorylase, XPRT, XPRTase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.22 xanthine phosphoribosyltransferase

KI Value

KI Value on EC 2.4.2.22 - xanthine phosphoribosyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.024
2,4-Dihydroxypteridine
-
-
0.0041
2,4-dihydroxypyrido[3,2-d]pyrimidine
-
-
0.41
2,6-dichloropurine
-
-
1.5
2,6-dioxo 3-isobutyl-1-methylpurine
-
-
1
2,6-dioxo-1,3,7-trimethylpurine
-
-
5.3
2,6-dioxo-1,3,9-trimethylpurine
-
-
1.9
2,6-dioxo-7-(beta-hydroxypropyl)-1,3-dimethylpurine
-
-
0.42
2,6-dithiopurine
-
-
0.15
2,6-dithioxanthine
-
-
0.04
2-amino 1-methylhypoxanthine
-
-
0.29
2-amino 1-methylpurine
-
-
0.23
2-amino-6-chloropurine
-
-
0.026
2-amino-7-deazahypoxanthine
-
-
3.1
2-amino-7-methylhypoxanthine
-
-
0.014
2-amino-9-deazahypoxanthine
-
-
0.23
2-amino-9-methylhypoxanthine
-
-
0.012
2-aminohypoxanthine
-
-
0.067
2-Aminopurine
-
-
0.002
2-aminopurine-6-thione
-
-
0.022
2-aza-3-deazahypoxanthine
-
-
0.231
2-aza-6-amino-3-deazapurine
-
-
0.03
2-aza-6-thio-3-deazapurine
-
-
0.17
2-hydroxy-6-methylthiopurine
-
-
1.4
2-oxo 1-methylhypoxanthine
-
-
1.9
2-oxo 7-methylhypoxanthine
-
-
0.246
2-oxo-6-thiopurine
-
-
0.014
2-oxohypoxanthine
-
-
1.3
2-oxohypoxanthine-N3-oxide
-
-
0.57
2-oxopurine
-
-
0.068
2-thiohypoxanthine
-
-
0.38
2-Thioxanthine
-
-
0.62
3-Methylxanthine
-
-
0.31
4,6-dihydroxypyrazolo[3,4-d]-pyrimidine
-
-
0.2
4-mercapto-6-hydroxypyrazolo[3,4-d]pyrimidine
-
-
0.379
4-oxopyrimidine
-
-
0.0079
5(4)-amino-4-imidazolecarboxamide
-
-
0.032
5,7-dihydroxy(1,2,5)thiadiazolo[3,4-d]pyrimidine
-
-
0.11
5,7-dihydroxy-v-triazolo[4,5-d]pyrimidine
-
-
0.0022
5,7-dihydroxypyrazolo[4,3-d]pyrimidine
-
-
0.657
5-fluorocytosine
-
-
0.021
5-phospho-alpha-D-ribose 1-diphosphate
-
-
0.31
6-amino 1-methylpurine
-
-
0.437
6-amino-2,8-diaza-3-deazapurine
-
-
2.2
6-amino-2-chloropurine
-
-
0.37
6-amino-2-methylpurine
-
-
0.053
6-amino-2-oxopurine
-
-
1.7
6-amino-7-deazapurine
-
-
0.75
6-amino-8-bromopurine
-
-
1.1
6-benzylaminopurine
-
-
0.1
6-Chloropurine
-
-
3.4
6-Hydroxymethylpterin
-
-
0.38
6-methoxypurine
-
-
0.97
6-Methylaminopurine
-
-
0.006
6-Thiopurine
-
-
0.34
6-Thioxanthine
-
-
5.2
8-aza-1,3-dideazapurine
-
-
0.39
8-aza-1-nitro-1,3-dideazapurine
-
-
0.85
8-aza-2,6-diaminopurine
-
-
2.6
8-aza-2-aminohypoxanthine
-
-
2.5
8-aza-6-aminopurine
-
-
0.88
8-aza-7-deaza 6-thiopurine
-
-
0.081
8-aza-7-deaza-6-aminopurine
-
-
0.035
8-aza-7-deazahypoxanthine
-
-
2
8-Azahypoxanthine
-
-
0.54
8-bromo-2-aminohypoxanthine
-
-
0.39
8-mercaptoxanthine
-
-
4.1
8-oxohypoxanthine
-
-
0.42
8-thiohypoxanthine
-
-
0.87
Benzonitrile
-
-
0.286
cytosine
-
-
0.033 - 0.067
GMP
0.0035
hypoxanthine
-
-
1.06
isocytosine
-
-
0.0025
pppGpp
at pH 7.6 and 25°C
0.808
Uracil
-
-
0.024
xanthine
-
-
0.000006
[3-(guanine-9-yl)-2-((2-phosphonoethoxy)methyl)propoxy]methylphosphonic acid
pH 7.4, temperature not specified in the publication