2.4.2.22: xanthine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about xanthine phosphoribosyltransferase, go to the full flat file.

Reaction

Synonyms

5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase, EcXGPRT, HGXPRT, hypoxanthine-guanine-(xanthine) phosphoribosyltransferase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, More, Pf HGXPRT, phosphoribosyltransferase, xanthine, ttha0535, TtXPRT, Xan phosphoribosyltransferase, xanthine phosphoribosyltransferase, xanthine PRT, xanthine-guanine PRT, xanthosine 5'-phosphate pyrophosphorylase, xanthylate pyrophosphorylase, xanthylic pyrophosphorylase, XGPRT , XMP pyrophosphorylase, XPRT, XPRTase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.2 Pentosyltransferases

                2.4.2.22 xanthine phosphoribosyltransferase

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Results	in table
1	Activating Compound
13958	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
2	Crystallization (Commentary)
9	General Information
2	General Stability
3	IC50 Value
157	Inhibitors
10	kcat/KM [mM/s]
82	Ki Value [mM]
69	KM Value [mM]
3	Localization
23	Metals/Ions
5	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
25	Organism
6	Pathway
28	PDB ID
8	pH Optimum
2	pH Range
1	pH Stability
9	Protein Variants
8	Purification (Commentary)
1	Reaction
1	Reaction Type
25	Reference
5	Source Tissue
4	Specific Activity [micromol/min/mg]
4	Storage Stability
64	Substrates and Products (Substrate)
9	Subunits
37	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
53	Turnover Number [1/s]

Cloned

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Cloned on EC 2.4.2.22 - xanthine phosphoribosyltransferase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

Escherichia coli Sphi606 or Sphi609 cells transformed with pSelect-LdXPRT, pSelectldxprtE198D, pSelect-ldxprtE215D, pSelect-ldxprtE215Q and pSelectldxprtE198,215D

Leishmania donovani

-

704046

expressed in Escherichia coli

Plasmodium falciparum

-

760104

expressed in Escherichia coli BL21(DE3) cells

Bacillus subtilis

P42085

759629

expression in Escherichia coli

Leishmania donovani

-

638009

expression of full length and C-terminally truncated enzymes in Escherichia coli

Leishmania donovani

-

659904

gene xprt, DNA and amino acid sequence determination and analysis, recombinant expression of N-terminally His6-tagged enzyme in Escherichia coli strain BL21(DE3)

Thermus thermophilus

Q5SKV8

758716

isolation and characterization of the XPT1 gene

Saccharomyces cerevisiae

-

638007