2.4.2.22: xanthine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about xanthine phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.22

2.4.2.22

purine

salvage

falciparum

plasmodium

6-oxopurine

phosphoribosylation

phosphoribosyltransferases

tritrichomonas

prtases

2.4.2.8

cho-k1-bh4

hgprts

2.7.1.20

psv2-gpt

medicine

Reaction

Synonyms

5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase, EcXGPRT, HGXPRT, hypoxanthine-guanine-(xanthine) phosphoribosyltransferase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, More, Pf HGXPRT, phosphoribosyltransferase, xanthine, ttha0535, TtXPRT, Xan phosphoribosyltransferase, xanthine phosphoribosyltransferase, xanthine PRT, xanthine-guanine PRT, xanthosine 5'-phosphate pyrophosphorylase, xanthylate pyrophosphorylase, xanthylic pyrophosphorylase, XGPRT , XMP pyrophosphorylase, XPRT, XPRTase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.2 Pentosyltransferases

2.4.2.22 xanthine phosphoribosyltransferase

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Results	in table
1	Activating Compound
13958	AA Sequence
1	Application
1	CAS Registry Number
7	Cloned(Commentary)
2	Crystallization (Commentary)
9	General Information
2	General Stability
3	IC50 Value
157	Inhibitors
10	kcat/KM [mM/s]
82	Ki Value [mM]
69	KM Value [mM]
3	Localization
23	Metals/Ions
5	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
25	Organism
6	Pathway
28	PDB ID
8	pH Optimum
2	pH Range
1	pH Stability
9	Protein Variants
8	Purification (Commentary)
1	Reaction
1	Reaction Type
25	Reference
5	Source Tissue
4	Specific Activity [micromol/min/mg]
4	Storage Stability
64	Substrates and Products (Substrate)
9	Subunits
37	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
53	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 2.4.2.22 - xanthine phosphoribosyltransferase

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5-phospho-alpha-D-ribose 1-diphosphate + 4,6-dihydroxypyrazolo[3,4-d]pyrimidine

Enterococcus faecalis

at 0.064% of the activity with xanthine

638005

5-phospho-alpha-D-ribose 1-diphosphate + 5,7-dihydroxy-v-triazolo[4,5-d]pyrimidine

Enterococcus faecalis

at 16.8% of the activity with xanthine

638005

5-phospho-alpha-D-ribose 1-diphosphate + adenine

AMP + diphosphate

2 entries

5-phospho-alpha-D-ribose 1-diphosphate + guanine

GMP + diphosphate

6 entries

5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine

IMP + diphosphate

9 entries

5-phospho-alpha-D-ribose 1-diphosphate + xanthine

9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate

14 entries

5-phospho-alpha-D-ribose 1-diphosphate + xanthine

XMP + diphosphate

3 entries

9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate

5-phospho-alpha-D-ribose 1-diphosphate + xanthine

Leishmania donovani

704046

guanine + 5-phospho-alpha-D-ribose 1-diphosphate

GMP + diphosphate

4 entries

guanosine + 5-phospho-alpha-D-ribose 1-diphosphate

GMP + diphosphate

Plasmodium falciparum

Q8IJS1

759601

hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate

IMP + diphosphate

5 entries

IMP + diphosphate

5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine

Leishmania donovani

704046

xanthine + 5-phospho-alpha-D-ribose 1-diphosphate

XMP + diphosphate

5 entries

additional information

6 entries