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2.4.2.22: xanthine phosphoribosyltransferase

This is an abbreviated version!
For detailed information about xanthine phosphoribosyltransferase, go to the full flat file.

Word Map on EC 2.4.2.22

Reaction

XMP
+
diphosphate
=
5-phospho-alpha-D-ribose 1-diphosphate
+
xanthine

Synonyms

5-phospho-alpha-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase, EcXGPRT, HGXPRT, hypoxanthine-guanine-(xanthine) phosphoribosyltransferase, hypoxanthine-guanine-xanthine phosphoribosyltransferase, More, Pf HGXPRT, phosphoribosyltransferase, xanthine, ttha0535, TtXPRT, Xan phosphoribosyltransferase, xanthine phosphoribosyltransferase, xanthine PRT, xanthine-guanine PRT, xanthosine 5'-phosphate pyrophosphorylase, xanthylate pyrophosphorylase, xanthylic pyrophosphorylase, XGPRT , XMP pyrophosphorylase, XPRT, XPRTase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.2 Pentosyltransferases
                2.4.2.22 xanthine phosphoribosyltransferase

Natural Substrates Products

Natural Substrates Products on EC 2.4.2.22 - xanthine phosphoribosyltransferase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
5-phospho-alpha-D-ribose 1-diphosphate + guanine
GMP + diphosphate
show the reaction diagram
-
-
-
-
?
5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine
IMP + diphosphate
show the reaction diagram
-
-
-
-
?
5-phospho-alpha-D-ribose 1-diphosphate + xanthine
9-(5-phospho-beta-D-ribosyl)xanthine + diphosphate
show the reaction diagram
-
the enzyme is involved in purine nucleotide synthesis via phosphorylation of purines acquisited from the host, since Leishmania donovani is not able to perform de novo biosynthesis of purine nucleotides
-
-
?
5-phospho-alpha-D-ribose 1-diphosphate + xanthine
XMP + diphosphate
show the reaction diagram
guanine + 5-phospho-alpha-D-ribose 1-diphosphate
GMP + diphosphate
show the reaction diagram
-
-
-
r
guanosine + 5-phospho-alpha-D-ribose 1-diphosphate
GMP + diphosphate
show the reaction diagram
-
-
-
?
hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
IMP + diphosphate
show the reaction diagram
reaction of EC 2.4.2.8
-
-
?
xanthine + 5-phospho-alpha-D-ribose 1-diphosphate
XMP + diphosphate
show the reaction diagram
additional information
?
-