2.4.1.15: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

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For detailed information about alpha,alpha-trehalose-phosphate synthase (UDP-forming), go to the full flat file.

Reaction

Synonyms

alpha,alpha-trehalose phosphate synthase (UDP-forming), alpha,alpha-trehalose-phosphate synthase (UDP-forming), AtTPS1, AtTPS6, GbTPS, glucosyltransferase, uridine diphosphoglucose phosphate, OtsA, OtsA1, OtsA2, phosphotrehalose-uridine diphosphate transglucosylase, T-6-P, T6P synthase, Ta1210, TPS, TPS-2, TPS-3, TPS1, TPS2, TPS3, TPS5, TPSP, transglucosylase, trehalose 6-phosphate synthase, trehalose 6-phosphate synthase 1, trehalose 6-phosphate synthetase, trehalose phosphate synthase, trehalose phosphate synthase 5, trehalose phosphate synthetase, trehalose phosphate-uridine diphosphate glucosyltransferase, trehalose-6-P synthase, trehalose-6-phosphate synthase, trehalose-6-phosphate synthase 1, trehalose-6-phosphate synthase/phosphatase, trehalose-6P synthase, trehalose-P synthetase, trehalosephosphate-UDP glucosyl transferase, UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase, UDPglucose-glucose-phosphate glucosyltransferase

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.15 alpha,alpha-trehalose-phosphate synthase (UDP-forming)

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Results	in table
52	Activating Compound
8087	AA Sequence
7	Application
1	CAS Registry Number
56	Cloned(Commentary)
7	Crystallization (Commentary)
12	Expression
49	General Information
5	General Stability
62	IC50 Value
153	Inhibitors
1	kcat/KM [mM/s]
2	Ki Value [mM]
49	KM Value [mM]
4	Localization
70	Metals/Ions
32	Molecular Weight [Da]
74	Natural Substrates/ Products (Substrates)
4	Organic Solvent Stability
124	Organism
6	Pathway
70	PDB ID
25	pH Optimum
9	pH Range
7	pH Stability
10	pI Value
4	Posttranslational Modification
30	Protein Variants
32	Purification (Commentary)
4	Reaction
7	Reaction Type
121	Reference
61	Source Tissue
42	Specific Activity [micromol/min/mg]
9	Storage Stability
199	Substrates and Products (Substrate)
45	Subunits
185	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
9	Temperature Range [°C]
9	Temperature Stability [°C]
7	Turnover Number [1/s]

General Stability

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General Stability on EC 2.4.1.15 - alpha,alpha-trehalose-phosphate synthase (UDP-forming)

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

heparin helps to retain both stability and activity of the final purified enzyme

Saccharomyces cerevisiae

-

702423

in phosphate or acetate buffers, the activity of TpS1 is decreased to 25% and 30%, respectively, of activity in Tris-HCl buffer

Actinoplanes sp.

A8QX04

690584

stabilization during purification, 10fold by addition of 20 mM MgCl2, 50 mM NaCl, 2 M glycine betaine and 5 mM mercaptoethanol

Halorhodospira halochloris

-

488594

stable to at least 4 successive freeze/thaw cycles

Dictyostelium discoideum

-

488597

stable to dialysis against either water or 0.1 M Tris-maleate buffer, pH 7.0

Hyalophora cecropia

-

488599