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2.4.1.15: alpha,alpha-trehalose-phosphate synthase (UDP-forming)

This is an abbreviated version!
For detailed information about alpha,alpha-trehalose-phosphate synthase (UDP-forming), go to the full flat file.

Word Map on EC 2.4.1.15

Reaction

UDP-alpha-D-glucose
+
D-glucose 6-phosphate
=
UDP
 +
alpha,alpha-trehalose 6-phosphate

Synonyms

alpha,alpha-trehalose phosphate synthase (UDP-forming), alpha,alpha-trehalose-phosphate synthase (UDP-forming), AtTPS1, AtTPS6, GbTPS, glucosyltransferase, uridine diphosphoglucose phosphate, OtsA, OtsA1, OtsA2, phosphotrehalose-uridine diphosphate transglucosylase, T-6-P, T6P synthase, Ta1210, TPS, TPS-2, TPS-3, TPS1, TPS2, TPS3, TPS5, TPSP, transglucosylase, trehalose 6-phosphate synthase, trehalose 6-phosphate synthase 1, trehalose 6-phosphate synthetase, trehalose phosphate synthase, trehalose phosphate synthase 5, trehalose phosphate synthetase, trehalose phosphate-uridine diphosphate glucosyltransferase, trehalose-6-P synthase, trehalose-6-phosphate synthase, trehalose-6-phosphate synthase 1, trehalose-6-phosphate synthase/phosphatase, trehalose-6P synthase, trehalose-P synthetase, trehalosephosphate-UDP glucosyl transferase, UDP-glucose:D-glucose-6-phosphate 1-alpha-D-glucosyltransferase, UDPglucose-glucose-phosphate glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.15 alpha,alpha-trehalose-phosphate synthase (UDP-forming)

Expression

Expression on EC 2.4.1.15 - alpha,alpha-trehalose-phosphate synthase (UDP-forming)

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
a transitory increase in the expression of TPS2 and TPS1 genes is promoted in wild-type cells inresponse to acute, but not to gentleoxidative exposure
-
both low temperature and accumulation of trehalose can inhibit OtsA expression, increase of trehalose in the first 2.3 h of cold shock
enzyme expression increases 24-48 h after heat treatment (37°C)
enzyme transcription is upregulated following bacterial challenge by Escherichia coli or Staphylococcus aureus
in the case of expression of the TPS-3 gene, drought resistant seedlings significantly increase during the first 30 min and again 2 h later to decrease to normal levels from 4 h until 72 h. In susceptible seedlings on the other hand, there was an upregulation in the expression of TPS-3 from 2 to 6 h, and then a downregulation of the expression to the 12 h after start of stress conditions
-
lipopolysaccharide treatment results in increase in expression, enzyme activity, and hemolymph trehalose levels
pathogen infection with Botrytis cinerea and Pseudomonas syringae upregulates isoform TPS5 expression. An isoform TPS5-interacting protein (multiprotein bridging factor 1c) is required for induced expression of isoform TPS5 during pathogen infections. The enzyme expression is upregulated by 0.1 mM methyl jasmonate and 2 mM salicylic acid treatments
the enzyme is highly expressed after pupation or before molting
-
the relative expression level of isoform TPS1 gradually increases from 0 h of 4th instar to the highest level at the adult stage. The relative expression level of isoform TPS2 increases obviously from the end of 4th instar and is higher in the whole 5th instar. The expression of isoform TPS3 is relatively higher at the end of the 5th instar and the early stage of adult
-
with the increase of the salt concentration in the medium, the expression of DvTPS has a slight decrease of 17% in 5 M NaCl compared with 0.5 M condition