Reference on EC 4.2.1.28 - propanediol dehydratase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Abeles, R.H.
Dehydrations requiring vitamin B12 coenzyme
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
5
481-497
1971
Klebsiella pneumoniae
-
Toraya, T.; Fukui, S.
Coenzyme B12-dependent propanediol dehydratase system. Ternary complex between apoenzyme, coenzyme, and substrate analog
Biochim. Biophys. Acta
284
536-548
1972
Klebsiella pneumoniae
Toraya, T.; Uesaka, M.; Kondo, M.; Fukui, S.
Dissociation of diol dehydrase into two different protein components
Biochem. Biophys. Res. Commun.
52
350-355
1973
Klebsiella pneumoniae
Toraya, T.
Diol dehydrase and glycerol dehydrase, coenzyme B12-dependent isozymes
Met. Ions Biol. Syst.
30
217-254
1994
Flavobacterium sp., Klebsiella pneumoniae, Salmonella enterica subsp. enterica serovar Typhimurium
-
Jensen, F.R.; Neese, R.A.
Relative enantiomer binding and reaction rates with propanediol dehydrase
Biochem. Biophys. Res. Commun.
62
816-821
1975
Klebsiella pneumoniae
Toraya, T.; Shirakashi, T.; Kosuga, T.; Fukui, S.
Substrate specificity of coenzyme B12-dependent diol dehydrase: glycerol as both a good substrate and a potent inactivator
Biochem. Biophys. Res. Commun.
69
475-480
1976
Klebsiella pneumoniae
Bachovchin, W.W.; Eagar Jr., R.G.; Moore, K.W.; Richards, J.H.
Mechanism of action of Adenosylcobalamin: glycerol and other substrate analogues as substrates and inactivators for propanediol dehydratase - kinetics, stereospecificity, and mechanism
Biochemistry
16
1082-1092
1977
Klebsiella pneumoniae
Poznanskaja, A.A.; Tanizawa, K.; Soda, K.; Toraya, T.; Fukui, S.
Coenzyme B12-dependent diol dehydrase: purification, subunit heterogeneity, and reversible association
Arch. Biochem. Biophys.
194
379-386
1979
Klebsiella pneumoniae
Moore, K.W.; Richards, J.H.
Stereospecificity and mechanism of adenosylcobalamin-dependent diol dehydratase. Catalysis and inactivation with meso- and DL-2,3-butanediols as substrates
Biochem. Biophys. Res. Commun.
87
1052-1057
1979
Klebsiella pneumoniae
Poppe, L.; Retey, J.
Kinetic investigations with inhibitors that mimic the posthomolysis intermediate in the reactions of coenzyme-B12-dependent glycerol dehydratase and diol deydratase
Eur. J. Biochem.
245
398-401
1997
Klebsiella pneumoniae
Toraya, T.; Abeles, R.H.
Inactivation of dioldehydrase in the presence of a coenzyme-B12 analog
Arch. Biochem. Biophys.
203
174-180
1980
Klebsiella pneumoniae
McGee, D.E.; Richards, J.H.
Purification and subunit characterization of propanediol dehydratase, a membrane-associated enzyme
Biochemistry
20
4293-4298
1981
Klebsiella pneumoniae
Toraya, T.; Fukui, S.
Diol dehydrase
B12 (Dolphin, D. ed. ) Wiley, New York
2
233-262
1982
Citrobacter freundii, Klebsiella pneumoniae, Propionibacterium freudenreichii
-
Forage, R.G.; Foster, M.A.
Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases
J. Bacteriol.
149
413-419
1982
Klebsiella pneumoniae
McGee, D.E.; Carroll, S.S.; Bond, M.W.
Diol dehydratase: N-terminal amino acid sequences and subunit stoichiometry
Biochem. Biophys. Res. Commun.
108
547-551
1982
Klebsiella pneumoniae
Schuetz, H.; Radler, F.
Propanediol-1,2-dehydratase and metabolism of glycerol of Lactobacillus brevis
Arch. Microbiol.
139
366-370
1984
Levilactobacillus brevis, Lentilactobacillus buchneri
-
Ichikawa, Y.; Horike, Y.; Mori, N.; Hosoi, N.; Kitamoto, Y.
Purification and properties of propanediol dehydratase from Propionibacterium freudenreichii
J. Ferment. Technol.
63
135-141
1985
Propionibacterium freudenreichii
-
Hartmanis, M.G.N.; Stadtman, T.C.
Diol metabolism and diol dehydratase in Clostridium glycoliticum
Arch. Biochem. Biophys.
245
144-152
1986
Terrisporobacter glycolicus
Tanizawa, K.; Nakijama, N.; Toraya, T.; Tanaka, H.; Soda, K.
Re-investigation of the protein structure of coenzyme-B12-dependent diol dehydrase
Z. Naturforsch. C
42
353-359
1986
Klebsiella pneumoniae
Masuda, J.; Yamaguchi, T.; Tobimatsu, T.; Toraya, T.; Suto, K.; Shibata, N.; Morimoto, Y.; Higuchi, Y.; Yasuoka, N.
Crystallization and preliminary X-ray study of two crystal forms of Klebsiella oxytoca diol dehydratase-cyanocobalamin complex
Acta Crystallogr. Sect. D
55
907-909
1999
Klebsiella pneumoniae
Toraya, T.; Mori, K.
A reactivating factor for coenzyme B12-dependent diol dehydratase
J. Biol. Chem.
274
3372-3377
1999
Klebsiella pneumoniae
Yamanishi, M.; Yamada, S.; Ishida, A.; Yamauchi, J.; Toraya, T.
EPR spectroscopic evidence for the mechanism-based inactivation of adenosylcobalamin-dependent diol dehydratase by coenzyme analogs
J. Biochem.
124
598-601
1998
Klebsiella pneumoniae
Schramm, E.; Schink, B.
Ether-cleaving enzyme and diol dehydratase involved in anaerobic polyethylene glycol degradation by a new Acetobacterium sp
Biodegradation
2
71-79
1991
Acetobacterium sp.
Ishida, A.; Toraya, T.
Adenosylcobinamide methyl phosphate as a pseudocoenzyme for diol dehydrase
Biochemistry
32
1535-1540
1993
Klebsiella pneumoniae
Tobimatsu, T.; Sakai, T.; Hashida, Y.; Mizoguchi, N.; Miyoshi, S.; Toraya, T.
Heterologous expression, purification, and properties of diol dehydratase, an adenosylcobalamin-dependent enzyme of Klebsiella oxytoca
Arch. Biochem. Biophys.
247
132-140
1997
Klebsiella pneumoniae
Hartmanis, M.G.N.
Diol dehydrase from Clostridium glycolyticum: the non-B12-dependent enzyme
Met. Ions Biol. Syst.
30
201-215
1994
Terrisporobacter glycolicus
-
Tobimatsu, T.; Kajiura, H.; Toraya, T.
Specificities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase
Arch. Microbiol.
174
81-88
2000
Klebsiella oxytoca, Klebsiella pneumoniae
Mori, K.; Toraya, T.
Mechanism of reactivation of coenzyme B12-dependent diol dehydratase by a molecular chaperone-like reactivating factor
Biochemistry
38
13170-13178
1999
Klebsiella oxytoca
Abend, A.; Bandarian, V.; Reed, G.H.; Frey, P.A.
Identification of cis-ethanesemidione as the organic radical derived from glycolaldehyde in the suicide inactivation of dioldehydrase and of ethanolamine ammonia-lyase
Biochemistry
39
6250-6257
2000
Salmonella enterica subsp. enterica serovar Typhimurium
Toraya, T.
Radical catalysis of B12 enzymes: structure, mechanism, inactivation, and reactivation of diol and glycerol dehydratases
Cell. Mol. Life Sci.
57
106-127
2000
Klebsiella oxytoca, Klebsiella pneumoniae
Sauvageot, N.; Pichereau, V.; Louarme, L.; Hartke, A.; Auffray, Y.; Laplace, J.M.
Purification, characterization and subunits identification of the diol dehydratase of Lactobacillus collinoides
Eur. J. Biochem.
269
5731-5737
2002
Secundilactobacillus collinoides
Fukuoka, M.; Yamada, S.; Miyoshi, S.; Yamashita, K.; Yamanishi, M.; Zou, X.; Brown, K.L.; Toraya, T.
Functions of the D-ribosyl moiety and the lower axial ligand of the nucleotide loop of coenzyme B(12) in diol dehydratase and ethanolamine ammonia-lyase reactions
J. Biochem.
132
935-943
2002
Klebsiella oxytoca
Shibata, N.; Nakanishi, Y.; Fukuoka, M.; Yamanishi, M.; Yasuoka, N.; Toraya, T.
Structural rationalization for the lack of stereospecificity in coenzyme B12-dependent diol dehydratase
J. Biol. Chem.
278
22717-22725
2003
Klebsiella oxytoca
Masuda, J.; Shibata, N.; Morimoto, Y.; Toraya, T.; Yasuoka, N.
How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex
Structure Fold. Des.
8
775-788
2000
Klebsiella oxytoca
Fukuoka, M.; Nakanishi, Y.; Hannak, R.B.; Krautler, B.; Toraya, T.
Homoadenosylcobalamins as probes for exploring the active sites of coenzyme B12-dependent diol dehydratase and ethanolamine ammonia-lyase
FEBS J.
272
4787-4796
2005
Klebsiella oxytoca
Tobimatsu, T.; Kawata, M.; Toraya, T.
The N-terminal regions of beta and gamma subunits lower the solubility of adenosylcobalamin-dependent diol dehydratase
Biosci. Biotechnol. Biochem.
69
455-462
2005
Klebsiella oxytoca
Mansoorabadi, S.O.; Magnusson, O.T.; Poyner, R.R.; Frey, P.A.; Reed, G.H.
Analysis of the Cob(II)alamin-5-deoxy-3,4-anhydroadenosyl radical triplet spin system in the active site of diol dehydrase
Biochemistry
45
14362-14370
2006
Salmonella enterica subsp. enterica serovar Typhimurium
Schwartz, P.A.; Frey, P.A.
Dioldehydrase: an essential role for potassium ion in the homolytic cleavage of the cobalt-carbon bond in adenosylcobalamin
Biochemistry
46
7293-7301
2007
Salmonella enterica subsp. enterica serovar Typhimurium
Kajiura, H.; Mori, K.; Shibata, N.; Toraya, T.
Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases
FEBS J.
274
5556-5566
2007
Klebsiella oxytoca, Klebsiella pneumoniae
Sakai, T.; Yamasaki, A.; Toyofuku, S.; Nishiki, T.; Yunoki, M.; Komoto, N.; Tobimatsu, T.; Toraya, T.
Construction and characterization of hybrid dehydratases between adenosylcobalamin-dependent diol and glycerol dehydratases
J. Nutr. Sci. Vitaminol.
53
102-108
2007
Klebsiella oxytoca, Klebsiella pneumoniae
Kawata, M.; Kinoshita, K.; Takahashi, S.; Ogura, K.; Komoto, N.; Yamanishi, M.; Tobimatsu, T.; Toraya, T.
Survey of Catalytic Residues and Essential Roles of Glutamate-aplpha170 and Aspartate-alpha335 in Coenzyme B12-dependent Diol Dehydratase
J. Biol. Chem.
281
18327-18334
2006
Klebsiella oxytoca
Schwartz, P.A.; Lobrutto, R.; Reed, G.H.; Frey, P.A.
Probing interactions from solvent-exchangeable protons and monovalent cations with the 1,2-propanediol-1-yl radical intermediate in the reaction of dioldehydrase
Protein Sci.
16
1157-1164
2007
Salmonella enterica subsp. enterica serovar Typhimurium
Tobimatsu, T.; Nishiki, T.; Morimoto, M.; Miyata, R.; Toraya, T.
Low-solubility glycerol dehydratase, a chimeric enzyme of coenzyme B(12)-dependent glycerol and diol dehydratases
Arch. Microbiol.
191
199-206
2008
Salmonella enterica, Klebsiella oxytoca, Klebsiella pneumoniae
Kinoshita, K.; Kawata, M.; Ogura, K.; Yamasaki, A.; Watanabe, T.; Komoto, N.; Hieda, N.; Yamanishi, M.; Tobimatsu, T.; Toraya, T.
Histidine-alpha143 assists 1,2-hydroxyl group migration and protects radical intermediates in coenzyme B12-dependent diol dehydratase
Biochemistry
47
3162-3173
2008
Klebsiella oxytoca
Ogura, K.; Kunita, S.; Mori, K.; Tobimatsu, T.; Toraya, T.
Roles of adenine anchoring and ion pairing at the coenzyme B12-binding site in diol dehydratase catalysis
FEBS J.
275
6204-6216
2008
Klebsiella oxytoca
Sriramulu, D.D.; Liang, M.; Hernandez-Romero, D.; Raux-Deery, E.; Luensdorf, H.; Parsons, J.B.; Warren, M.J.; Prentice, M.B.
Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation
J. Bacteriol.
190
4559-4567
2008
Limosilactobacillus reuteri
Toraya, T.; Tamura, N.; Watanabe, T.; Yamanishi, M.; Hieda, N.; Mori, K.
Mechanism-based inactivation of coenzyme B12-dependent diol dehydratase by 3-unsaturated 1,2-diols and thioglycerol
J. Biochem.
144
437-446
2008
Klebsiella oxytoca
Parsons, J.B.; Dinesh, S.D.; Deery, E.; Leech, H.K.; Brindley, A.A.; Heldt, D.; Frank, S.; Smales, C.M.; Luensdorf, H.; Rambach, A.; Gass, M.H.; Bleloch, A.; McClean, K.J.; Munro, A.W.; Rigby, S.E.; Warren, M.J.; Prentice, M.B.
Biochemical and structural insights into bacterial organelle form and biogenesis
J. Biol. Chem.
283
14366-14375
2008
Citrobacter freundii (B1VB64), Citrobacter freundii (B1VB65), Citrobacter freundii (B1VB66)
Toraya, T.; Honda, S.; Mori, K.
Coenzyme B12-dependent diol dehydratase is a potassium ion-requiring calcium metalloenzyme: evidence that the substrate-coordinated metal ion is calcium
Biochemistry
49
7210-7217
2010
Klebsiella oxytoca, Klebsiella oxytoca ATCC 8724
Mori, K.; Hosokawa, Y.; Yoshinaga, T.; Toraya, T.
Diol dehydratase-reactivating factor is a reactivase - evidence for multiple turnovers and subunit swapping with diol dehydratase
FEBS J.
277
4931-4943
2010
Klebsiella oxytoca (Q59470), Klebsiella oxytoca (Q59471), Klebsiella oxytoca (Q59472)
Kamachi, T.; Doitomi, K.; Takahata, M.; Toraya, T.; Yoshizawa, K.
Catalytic roles of the metal ion in the substrate-binding site of coenzyme B12-dependent diol dehydratase
Inorg. Chem.
50
2944-2952
2011
Klebsiella oxytoca
Fan, C.; Bobik, T.A.
The N-terminal region of the medium subunit (PduD) packages adenosylcobalamin-dependent diol dehydratase (PduCDE) into the Pdu microcompartment
J. Bacteriol.
193
5623-5628
2011
Salmonella enterica
Wei, X.; Meng, X.; Chen, Y.; Wei, Y.; Du, L.; Huang, R.
Cloning, expression, and characterization of coenzyme-B12-dependent diol dehydratase from Lactobacillus diolivorans
Biotechnol. Lett.
36
159-165
2014
Lentilactobacillus diolivorans, Lentilactobacillus diolivorans DSM 14421
Yamanishi, M.; Kinoshita, K.; Fukuoka, M.; Saito, T.; Tanokuchi, A.; Ikeda, Y.; Obayashi, H.; Mori, K.; Shibata, N.; Tobimatsu, T.; Toraya, T.
Redesign of coenzyme B12 dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols
FEBS J.
279
793-804
2012
Klebsiella oxytoca (Q59470), Klebsiella oxytoca ATCC 8724 (Q59470)
Shibata, N.; Sueyoshi, Y.; Higuchi, Y.; Toraya, T.
Direct participation of a peripheral side chain of a corrin ring in coenzyme B12 catalysis
Angew. Chem. Int. Ed. Engl.
57
7830-7835
2018
Klebsiella oxytoca (Q59470)
Toraya, T.; Tanokuchi, A.; Yamasaki, A.; Nakamura, T.; Ogura, K.; Tobimatsu, T.
Diol dehydratase-reactivase is essential for recycling of coenzyme B12 in diol dehydratase
Biochemistry
55
69-78
2016
Klebsiella oxytoca (Q59470 and Q59471 and Q59472), Klebsiella oxytoca, Klebsiella oxytoca ATCC 8724 (Q59470 and Q59471 and Q59472)
Levin, B.J.; Balskus, E.P.
Characterization of 1,2-propanediol dehydratases reveals distinct mechanisms for B12-dependent and glycyl radical enzymes
Biochemistry
57
3222-3226
2018
Roseburia inulinivorans, Klebsiella oxytoca (Q59470 and Q59471 and Q59472), Roseburia inulinivorans A2-194, Klebsiella oxytoca ATCC 8724 (Q59470 and Q59471 and Q59472)
Doitomi, K.; Kamachi, T.; Toraya, T.; Yoshizawa, K.
Computational mutation study of the roles of catalytic residues in coenzyme B12-dependent diol dehydratase
Bull. Chem. Soc. JPN
89
955-964
2016
Klebsiella oxytoca (Q59470)
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