show all | hide all No of entries

Information on EC 4.1.1.21 - phosphoribosylaminoimidazole carboxylase

for references in articles please use BRENDA:EC4.1.1.21
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.1 Carboxy-lyases
                4.1.1.21 phosphoribosylaminoimidazole carboxylase
IUBMB Comments
While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in Escherichia coli, namely EC 6.3.4.18, 5-(carboxyamino)imidazole ribonucleotide synthase and EC 5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase . 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate.
Specify your search results
Select one or more organisms in this record:
Word Map
  • 4.1.1.21
  • saicar
  • n5-cair
  • 6.3.2.6
  • 4-carboxy-5-aminoimidazole
  • aircs
  • n5-carboxyaminoimidazole
  • samdc
  • analysis
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
paics, air carboxylase, class ii pure, aminoimidazole ribonucleotide carboxylase, phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2
show the reaction diagram
-
-
-
-
Select items on the left to see more content.