Ligand 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole

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Basic Ligand Information

Molecular Structure
Picture of 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H14N3O7P
5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
PDACUKOKVHBVHJ-XVFCMESISA-N
Synonyms:
1-(5'-phosphoribosyl)-5-aminoimidazole, 1-(5-phosphoribosyl)-5-aminoimidazole, 5'-phosphoribosyl-5-aminoimidazole, 5-amino-1(5-phospho-D-ribosyl)imidazole, 5-amino-1-(5-phospho-D-ribosyl)imidazole, 5-amino-1-beta-D-ribofuranosylimidazole 5'-phosphate, 5-aminoimidazole ribonucleotide, 5-phosphoribosyl-5-aminoimidazole, aminoimidazole ribotide, m-cresyl alpha-D-galactoside


Show all pahtways known for Show all BRENDA pathways known for 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine + reduced acceptor = 5-hydroxybenzimidazole + 5'-deoxyadenosine + L-methionine + formate + NH3 + phosphate + oxidized acceptor
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
m-cresyl alpha-D-galactoside + H2O = m-cresol + D-galactose
show the reaction diagram
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5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + S-adenosyl-L-methionine + reduced acceptor = 5-hydroxybenzimidazole + 5'-deoxyadenosine + L-methionine + formate + NH3 + phosphate + oxidized acceptor
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + 5-amino-1-(beta-D-ribosyl)imidazole = ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (10 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
40
-
-

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.017
-
pH 8.0, 37C, recombinant His-tagged enzyme

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.006
-
-

References & Links

Links to other databases for 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole

ChEBI
PubChem
ChEBI
PubChem