EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    4.1.1.21 | Abortion, Spontaneous |
31600779 |
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome. |
causal interaction
unassigned |
4
0 |
| 4.1.1.21 | Adenocarcinoma of Lung |
26140362 |
Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
3
2
1
0 |
| 4.1.1.21 | Adenocarcinoma of Lung |
30641222 |
Roles of highly expressed PAICS in lung adenocarcinoma. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 4.1.1.21 | Breast Neoplasms |
28411283 |
Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
2
3
3 |
| 4.1.1.21 | Breast Neoplasms |
30097015 |
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
4 |
| 4.1.1.21 | Breast Neoplasms |
30641222 |
Roles of highly expressed PAICS in lung adenocarcinoma. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 4.1.1.21 | Carcinogenesis |
30097015 |
Knockdown of PAICS inhibits malignant proliferation of human breast cancer cell lines. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
1
4
4 |
| 4.1.1.21 | Carcinogenesis |
32632107 |
PAICS contributes to gastric carcinogenesis and participates in DNA damage response by interacting with histone deacetylase 1/2. |
causal interaction
unassigned |
4
0 |
| 4.1.1.21 | Carcinoma, Non-Small-Cell Lung |
34323174 |
Regulating COX10-AS1 / miR-142-5p / PAICS axis inhibits the proliferation of non-small cell lung cancer. |
therapeutic application
unassigned |
1
0 |
| 4.1.1.21 | Colorectal Neoplasms |
32218208 |
PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
