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BRENDA support

Ligand carbon dioxide

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Basic Ligand Information

Molecular Structure
Picture of carbon dioxide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
CO2
carbon dioxide
CURLTUGMZLYLDI-UHFFFAOYSA-N
Synonyms:
carbondioxide, CO2
Pathway Source
Pathways
BRENDA
(5R)-carbapenem carboxylate biosynthesis, (S)-reticuline biosynthesis, 4-hydroxymandelate degradation, 4-hydroxyphenylacetate degradation, acetate fermentation more
KEGG
Arginine biosynthesis, Atrazine degradation, Bile secretion, Biosynthesis of amino acids, Carbohydrate digestion and absorption more
MetaCyc
(-)-4'-demethyl-epipodophyllotoxin biosynthesis, (-)-dehydrodiconiferyl alcohol degradation, (-)-microperfuranone biosynthesis, (1'S,5'S)-averufin biosynthesis, (2-trimethylamino)ethylphosphonate degradation more


Show all pahtways known for Show all BRENDA pathways known for carbon dioxide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (93 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
pyruvate + CO2 + NADH + H+ = (S)-malate + NAD+
show the reaction diagram
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2-oxoglutarate + CO2 + NADPH + H+ = isocitrate + NADP+
show the reaction diagram
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CO2 + NADPH = formate + NADP+
show the reaction diagram
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CO2 + NADH = formate + NAD+
show the reaction diagram
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5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH = glycine + tetrahydrofolate + NAD+
show the reaction diagram
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CO2 + H2O = HCO3- + H+
show the reaction diagram
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CO2 + reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + H+ = formate + oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB
show the reaction diagram
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2 S-adenosyl-L-methionine + 7-((3S)-3-amino-3-carboxypropyl)wyosine + CO2 = 2 S-adenosyl-L-homocysteine + wybutosine
show the reaction diagram
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beta-nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
show the reaction diagram
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ATP + NH3 + CO2 = ADP + carbamoyl phosphate
show the reaction diagram
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L-threonine + ATP + CO2 = L-threonylcarbamoyl-AMP + diphosphate
show the reaction diagram
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phenyl phosphate + CO2 + H2O = 4-hydroxybenzoate + phosphate
show the reaction diagram
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1-(5-Phosphoribosyl)-5-aminoimidazole + CO2 = ?
show the reaction diagram
Phenol + CO2 = ?
show the reaction diagram
ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein
show the reaction diagram
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ATP + urea + CO2 = ADP + phosphate + urea-1-carboxylate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1050 results)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
6-phospho-D-gluconate + NAD+ = D-ribulose 5-phosphate + CO2 + NADH + H+
show the reaction diagram
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D-malate + NAD+ = pyruvate + CO2 + NADH
show the reaction diagram
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(R)-3,3-dimethylmalate + NAD+ = 3-methyl-2-oxobutanoate + CO2 + NADH
show the reaction diagram
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2-hydroxy-3-oxosuccinate + NAD(P)H = D-glycerate + NAD(P)+ + CO2
show the reaction diagram
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(S)-lactate + O2 = acetate + CO2 + H2O
show the reaction diagram
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(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2
show the reaction diagram
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3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + O2 = grixazone B + H2O + CO2
show the reaction diagram
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palmitate + H2O2 = pentadecanal + CO2 + H2O
show the reaction diagram
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2,3-dihydroxybenzoate + O2 = CO2 + alpha-hydroxymuconic semialdehyde
show the reaction diagram
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2,3-dihydroxyindole + O2 = anthranilate + CO2
show the reaction diagram
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4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2
show the reaction diagram
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3-dimethylallyl-4-hydroxyphenylpyruvate + O2 = 3-dimethylallyl-4-hydroxymandelate + CO2
show the reaction diagram
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2-oxoadipate + O2 = (R)-2-hydroxyglutarate + CO2
show the reaction diagram
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L-lysine + O2 = 5-aminopentanamide + CO2 + H2O
show the reaction diagram
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3-dimethylallyl-4-hydroxymandelate + O2 = 3-dimethylallyl-4-hydroxybenzoate + CO2 + H2O
show the reaction diagram
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[apoaequorin] + coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
show the reaction diagram
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(S)-lactate + O2 = acetate + CO2 + H2O
show the reaction diagram
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Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + hv
show the reaction diagram
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Arachnocampa luciferin + O2 + ATP = Arachnocampa oxyluciferin + CO2 + AMP + diphosphate + hv
show the reaction diagram
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4-trimethylammoniobutanoate + 2-oxoglutarate + O2 = 3-hydroxy-4-trimethylammoniobutanoate + succinate + CO2
show the reaction diagram
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2'-deoxyuridine + 2-oxoglutarate + O2 = uracil + deoxyribonolactone + succinate + CO2
show the reaction diagram
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gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2
show the reaction diagram
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taurine + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2
show the reaction diagram
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phytanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyphytanoyl-CoA + succinate + CO2
show the reaction diagram
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deacetoxyvindoline + 2-oxoglutarate + O2 = deacetylvindoline + succinate + CO2
show the reaction diagram
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L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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hypoxia-inducible factor-L-asparagine + 2-oxoglutarate + O2 = hypoxia-inducible factor-(3S)-3-hydroxy-L-asparagine + succinate + CO2
show the reaction diagram
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kanamycin B + 2-oxoglutarate + O2 = 2'-dehydrokanamycin A + succinate + NH3 + CO2
show the reaction diagram
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fumitremorgin B + 2-oxoglutarate + 2 O2 + AH2 = verruculogen + succinate + CO2 + H2O + A
show the reaction diagram
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L-asparagine + 2-oxoglutarate + O2 = (2S,3S)-3-hydroxyasparagine + succinate + CO2
show the reaction diagram
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L-enduracididine + 2-oxoglutarate + O2 = (3S)-3-hydroxy-L-enduracididine + succinate + CO2
show the reaction diagram
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7-(3-amino-3-carboxypropyl)wyosine37 in tRNAPhe + 2-oxoglutarate + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine37 in tRNAPhe + succinate + CO2
show the reaction diagram
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(2-aminoethyl)phosphonate + 2-oxoglutarate + O2 = (2-amino-1-hydroxyethyl)phosphonate + succinate + CO2
show the reaction diagram
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[50S ribosomal protein L16]-L-Arg81 + 2-oxoglutarate + O2 = [50S ribosomal protein L16]-(3R)-3-hydroxy-L-Arg81 + succinate + CO2
show the reaction diagram
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xanthine + 2-oxoglutarate + O2 = urate + succinate + CO2
show the reaction diagram
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UMP + 2-oxoglutarate + O2 = 5'-dehydrouridine + succinate + CO2 + phosphate
show the reaction diagram
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N6-methyladenine in DNA + 2-oxoglutarate + O2 = adenine in DNA + formaldehyde + succinate + CO2
show the reaction diagram
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validamycin A + 2-oxoglutarate + O2 = validamycin B + succinate + CO2
show the reaction diagram
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L-proline + 2-oxoglutarate + O2 = trans-4-hydroxy-L-proline + succinate + CO2
show the reaction diagram
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scopoletin + 2-oxoglutarate + O2 = fraxetin + succinate + CO2
show the reaction diagram
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trans-feruloyl-CoA + 2-oxoglutarate + O2 = trans-6-hydroxyferuloyl-CoA + succinate + CO2
show the reaction diagram
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a [protein]-L-lysine + 2-oxoglutarate + O2 = a [protein]-(3S)-3-hydroxy-L-lysine + succinate + CO2
show the reaction diagram
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methylphosphonate + 2-oxoglutarate + O2 = hydroxymethylphosphonate + succinate + CO2
show the reaction diagram
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[2-(trimethylamino)ethyl]phosphonate + 2-oxoglutarate + O2 = [(1R)-1-hydroxy-2-(trimethylamino)ethyl]phosphonate + succinate + CO2
show the reaction diagram
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L-isoleucine + 2-oxoglutarate + O2 = (3S)-3'-hydroxy-L-isoleucine + succinate + CO2
show the reaction diagram
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(3S)-3'-hydroxy-L-isoleucine + 2-oxoglutarate + O2 = (3S,4R)-3',4-dihydroxy-L-isoleucine + succinate + CO2
show the reaction diagram
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S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH] + 2-oxoglutarate + O2 = S-(erythro-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH] + succinate + CO2
show the reaction diagram
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S-(L-glutamyl)-[peptidyl-carrier protein of nonribosomal peptide synthetase KtzH] + 2-oxoglutarate + O2 = S-(threo-3-hydroxy-L-glutamyl)-[peptidyl-carrier-protein of nonribosomal peptide synthetase KtzH] + succinate + CO2
show the reaction diagram
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luciferin + O2 + ATP = oxyluciferin + AMP + diphosphate + CO2 + light
show the reaction diagram
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6-hydroxynicotinate + NADH + H+ + O2 = 2,5-dihydroxypyridine + NAD+ + H2O + CO2
show the reaction diagram
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(indol-3-yl)pyruvate + NADPH + H+ + O2 = (indol-3-yl)acetate + NADP+ + H2O + CO2
show the reaction diagram
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5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
show the reaction diagram
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2-(L-cystein-S-yl)-2-(1H-indol-3-yl)acetonitrile + [reduced NADPH-hemoprotein reductase] + O2 = camalexin + hydrogen cyanide + CO2 + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
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(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = 3-[(Z)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
show the reaction diagram
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(2S)-3-(1H-indol-3-yl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = 3-[(E)-2-isocyanoethenyl]-1H-indole + succinate + 2 CO2 + H2O
show the reaction diagram
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L-threonyl-[L-threonyl-carrier protein SyrB1] + 2-oxoglutarate + O2 + Cl- = 4-chloro-L-threonyl-[L-threonyl-carrier protein SyrB1] + succinate + CO2 + H2O
show the reaction diagram
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2R,3S,4S-cis-leucoanthocyanidin + 2-oxoglutarate + O2 = cis- and trans-dihydroquercetins + succinate + CO2 + 2 H2O
show the reaction diagram
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(-)-yatein + 2-oxoglutarate + O2 = (-)-deoxypodophyllotoxin + succinate + CO2 + H2O
show the reaction diagram
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(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + succinate + CO2 + H2O
show the reaction diagram
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Latia luciferin + AH2 + O2 = oxidized Latia luciferin + CO2 + formate + A + H2O + hnu
show the reaction diagram
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formate + NADP+ = CO2 + NADPH
show the reaction diagram
-
formate + oxidized coenzyme F420 = CO2 + reduced coenzyme F420
show the reaction diagram
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3-oxopropanoate + CoA + NAD+ = acetyl-CoA + CO2 + NADH
show the reaction diagram
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pyruvate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH
show the reaction diagram
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2-oxoglutarate + CoA + NADP+ = succinyl-CoA + CO2 + NADPH
show the reaction diagram
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phenylglyoxylate + NAD+ + CoA-SH = benzoyl-S-CoA + CO2 + NADH
show the reaction diagram
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4-hydroxyphenylpyruvate + O2 = 4-hydroxyphenylacetate + CO2
show the reaction diagram
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oxalate + oxidized ferredoxin = CO2 + reduced ferredoxin
show the reaction diagram
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4-amino-4-deoxyprephenate + NAD+ = 3-(4-aminophenyl)pyruvate + CO2 + NADH + H+
show the reaction diagram
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(-)-3,5-cyclohexadiene-1,2-diol-1-carboxylic acid + NAD+ = catechol + CO2 + NADH
show the reaction diagram
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L-arogenate + NAD+ = L-tyrosine + NADH + CO2
show the reaction diagram
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benzylmalonyl-CoA + O2 = (E)-cinnamoyl-CoA + CO2 + H2O2
show the reaction diagram
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C-terminal [mycofactocin precursor peptide MftA]-glycyl-L-valyl-L-tyrosine + S-adenosyl-L-methionine = C-terminal [mycofactocin precursor peptide MftA]-glycyl-L-valyl-4-[2-aminoethenyl]phenol + CO2 + 5'-deoxyadenosine + L-methionine
show the reaction diagram
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cypemycin(1-18)-L-Cys-L-Leu-L-Val-L-Cys + acceptor = C3.19,S21-cyclocypemycin(1-18)-L-Ala-L-Leu-N-thioethenyl-L-valinamide + CO2 + H2S + reduced acceptor
show the reaction diagram
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glycine + tetrahydrofolate + NAD+ = 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH
show the reaction diagram
-
2-mercaptoethanesulfonate + acetoacetate + NADP+ = 2-(2-oxopropylthio)ethanesulfonate + CO2 + NADPH + H+
show the reaction diagram
2 formate + 2 oxidized ferredoxin [iron-sulfur] cluster + CoM-S-S-CoB = 2 CO2 + 2 reduced ferredoxin [iron-sulfur] cluster + CoB + CoM + 2 H+
show the reaction diagram
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cobalt-precorrin-6B + S-adenosyl-L-methionine = cobalt-precorrin-7 + S-adenosyl-L-homocysteine + CO2
show the reaction diagram
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pyruvate + (E)-oct-2-enal = (S)-3-acetyloctanal + CO2
show the reaction diagram
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2-oxoglutarate + glyoxylate = 2-hydroxy-3-oxoadipate + CO2
show the reaction diagram
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eicosanoyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + 8 H+ = tetramethyl-branched mycocerosoyl-CoA + 4 CoA + 4 CO2 + 8 NADP+ + 4 H2O
show the reaction diagram
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cinnamoyl-CoA + malonyl-CoA = 3,5-dihydroxystilbene + CoA + CO2
show the reaction diagram
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benzoyl-CoA + 3 malonyl-CoA = 2,4,6-trihydroxybenzophenone + 4 CoA + 3 CO2
show the reaction diagram
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malonyl-CoA + N-methylanthraniloyl-CoA = CoA + 1,3-dihydroxy-N-methylacridone + CO2
show the reaction diagram
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malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = CoA + isoliquiritigenin + CO2 + NADP+ + H2O
show the reaction diagram
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3 malonyl-CoA + hexanoyl-CoA = 3 CoA + 3,5,7-trioxododecanoyl-CoA + 3 CO2
show the reaction diagram
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octanoyl-CoA + malonyl-[acyl-carrier protein] = 3-oxodecanoyl-[acyl-carrier protein] + CoA + CO2
show the reaction diagram
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4-coumaroyl-CoA + malonyl-CoA + H2O = 2 CoA + 4-hydroxybenzalacetone + 2 CO2
show the reaction diagram
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5 malonyl-CoA = 5 CoA + 5,7-dihydroxy-2-methyl-4H-chromen-4-one + 5 CO2 + H2O
show the reaction diagram
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3 malonyl-CoA + benzoyl-CoA = 4 CoA + 2,4,6-trihydroxybenzophenone + 3 CO2
show the reaction diagram
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7 malonyl-CoA + hexanoyl-[acyl-carrier protein] = 7 CoA + norsolorinic acid anthrone + [acyl-carrier protein] + 7 CO2 + 2 H2O
show the reaction diagram
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10 malonyl-CoA = tetracenomycin F2 + 10 CoA + 10 CO2 + 2 H2O
show the reaction diagram
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acetyl-CoA + 5 malonyl-CoA + 3 NADPH + 3 H+ = 5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 4 H2O + 3 NADP+
show the reaction diagram
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acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+ = 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+
show the reaction diagram
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malonyl-CoA + 5 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+ = 10-deoxymethynolide + 6 CoA + 6 CO2 + 5 NADP+ + 2 H2O
show the reaction diagram
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malonyl-CoA + 6 (2S)-methylmalonyl-CoA + 5 NADPH + 5 H+ = narbonolide + 7 CoA + 7 CO2 + 5 NADP+ + 2 H2O
show the reaction diagram
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acetyl-CoA + malonyl-CoA + [2-methylbutanoate polyketide synthase] + 2 NADPH + 2 H+ + S-adenosyl-L-methionine = (S)-2-methylbutanoyl-[2-methylbutanoate polyketide synthase] + 2 CoA + CO2 + 2 NADP+ + S-adenosyl-L-homocysteine + H2O
show the reaction diagram
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a long-chain acyl-CoA + 3 (R)-methylmalonyl-CoA + 6 NADPH + 6 H+ + holo-[mycolipanoate synthase] = mycolipanoyl-[mycolipanoate synthase] + 4 CoA + 3 CO2 + 6 NADP+ + 3 H2O
show the reaction diagram
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3 malonyl-CoA = phloroglucinol + 3 CO2 + 3 CoA
show the reaction diagram
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malonamoyl-[OxyC acyl-carrier protein] + malonyl-CoA = 18-carbamoyl-3,5,7,9,11,13,15,17-octaoxooctadecanoyl-[OxyC acyl-carrier protein] + CO2 + CoA
show the reaction diagram
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a medium-chain acyl-CoA + 5 malonyl-CoA + 5 (S)-methylmalonyl-CoA + 22 NADPH + 22 H+ = a mycoketide-CoA + 10 CO2 + 10 CoA + 22 NADP+ + 11 H2O
show the reaction diagram
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succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2
show the reaction diagram
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acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O
show the reaction diagram
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8 malonyl-CoA + NADPH + H+ = 8 CoA + (4E,6E,8E,10E,12E,14E)-3-hydroxyhexadeca-4,6,8,10,12,14-hexaenoic acid + NADP+ + H2O + CO2
show the reaction diagram
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geranylgeranyl diphosphate + homogentisate = diphosphate + 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2
show the reaction diagram
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octaprenyl diphosphate + 1,4-dihydroxy-2-naphthoate = a demethylmenaquinol + diphosphate + CO2
show the reaction diagram
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pimeloyl-[acyl-carrier protein] + L-alanine = 8-amino-7-oxononanoate + CO2 + holo-[acyl-carrier protein]
show the reaction diagram
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ADP + carbamoyl phosphate = ATP + NH3 + CO2
show the reaction diagram
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polyneuridine aldehyde + H2O = 16-epivellosimine + CO2 + methanol
show the reaction diagram
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pheophorbide a + H2O = pyropheophorbide a + methanol + CO2
show the reaction diagram
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carbonyl sulfide + H2O = hydrogen sulfide + CO2
show the reaction diagram
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L-citrulline + H2O = L-ornithine + CO2 + NH3
show the reaction diagram
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N-carbamoylputrescine + H2O = putrescine + CO2 + NH3
show the reaction diagram
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N-carbamoylsarcosine + H2O = sarcosine + CO2 + NH3
show the reaction diagram
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biuret + H2O = urea + CO2 + NH3
show the reaction diagram
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cyanuric acid + H2O = biuret + CO2
show the reaction diagram