Information on EC 1.4.1.14 - glutamate synthase (NADH)

for references in articles please use BRENDA:EC1.4.1.14
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IUBMB Comments
A flavoprotein (FMN). The reaction takes place in the direction of L-glutamate production. The protein is composed of two domains, one hydrolysing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2, glutaminase), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2, glutamate dehydrogenase).
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
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2
L-glutamate
+
NAD+
=
L-glutamine
+
2-oxoglutarate
+
NADH
+
H+
2
+
=
+
+
+
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