Ligand NADH

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Basic Ligand Information

Molecular Structure
Picture of NADH (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H29N7O14P2
NADH
BOPGDPNILDQYTO-NNYOXOHSSA-N
Synonyms:
beta-NADH

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (728 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-xylulose + NADH = L-xylitol + NAD+
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4-oxo-proline + NADH = 4-hydroxy-L-proline + NAD+
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D-ribulose + NADH + H+ = D-arabinitol + NAD+
show the reaction diagram
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2,5-didehydro-3-deoxy-D-gluconate + NADH + H+ = 2-dehydro-3-deoxy-D-gluconate + NAD+
show the reaction diagram
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D-fructose 6-phosphate + NADH = D-sorbitol 6-phosphate + NAD+
show the reaction diagram
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(5Z,13E)-11alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + NADH = (5Z,13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD+
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hexadecanal + NADH = hexadecanol + NAD+
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2-dehydropantoate + NADH + H+ = (R)-pantoate + NAD+
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D-fructose 6-phosphate + NADH + H+ = D-mannitol 1-phosphate + NAD+
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2-oxoadipate + NADH = 2-hydroxyadipate + NAD+
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12-ketochenodeoxycholic acid + NADH = cholic acid + NAD+
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indole-3-acetaldehyde + NADH = indole-3-ethanol + NAD+
show the reaction diagram
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cinnamaldehyde + NADH + H+ = cinnamyl alcohol + NAD+
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L-usnic acid + NADH = NAD+ + 2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methyl-phenyl)-3-hydroxy-6-methyl-cyclohexa-2,4-dienone
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acetoacetyl-[acyl-carrier protein] + NADH = 3-hydroxybutanoyl-[acyl-carrier protein] + NAD+
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3-(4-hydroxyphenyl)pyruvate + NADH + H+ = 3-(4-hydroxyphenyl)lactate + NAD+
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3-dehydroquinate + NADH = quinate + NAD+
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D-ribulose + NADH = D-arabinitol + NAD+
show the reaction diagram
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D-talose + NADH = D-altritol + NAD+
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6-methylhept-5-en-2-one + NADH = 6-methylhept-5-en-2-ol + NAD+
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2-formylglutarate + NADH + H+ = 2-hydroxymethylglutarate + NAD+
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diacetyl + NADH + H+ = (R)-acetoin + NAD+
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diacetyl + NADH + H+ = (S)-acetoin + NAD+
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D-xylose + NADH + H+ = xylitol + NAD+
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phosphonoacetaldehyde + NADH + H+ = 2-hydroxyethylphosphonate + NAD+
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a 2-oxocarboxylate + NADH + H+ = (2S)-2-hydroxycarboxylate + NAD+
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3-oxoacyl-CoA + NADH = 3-hydroxyacyl-CoA + NAD+
show the reaction diagram
dTDP-4-dehydro-6-deoxy-alpha-D-gulopyranose + NADH + H+ = dTDP-6-deoxy-alpha-D-allopyranose + NAD+
show the reaction diagram
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3-sulfolactaldehyde + NADH + H+ = 2,3-dihydroxypropane-1-sulfonate + NAD+
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12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+ = 3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+
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2-oxoglutarate + NADH + H+ = (R)-2-hydroxyglutarate + NAD+
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2,3,5,6-tetrachloro-1,4-benzoquinone + NADH + H+ = 2,3,5,6-tetrachlorohydroquinone + NAD+
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5alpha-dihydrotestosterone + NADH = 3alpha-androstanediol + NAD+
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tartronate semialdehyde + NADH = (R)-glycerate + NAD+
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D-fructose + NADH + H+ = D-mannitol + NAD+
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5-dehydro-D-gluconate + NADH + H+ = D-gluconate + NAD+
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retinaldehyde + NADH = retinol + NAD+
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(2S)-acetoin + NADH + H+ = (2S,3S)-butane-2,3-diol + NAD+
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methylglyoxal + NADH = (R)-lactaldehyde + NAD+
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hydroxypyruvate + NADH + H+ = D-glycerate + NAD+
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D-xylulose + NADH + H+ = xylitol + NAD+
show the reaction diagram
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norsolorinate + NADH + H+ = (1'S)-averantin + NAD+
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17,21-dihydroxy-pregn-4-ene-3,11,20-trione + NADH = 11beta,17,21-trihydroxy-pregn-4-ene-3,20-dione + NAD+
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3-quinuclidinone + NADH + H+ = (R)-3-quinuclidinol + NAD+
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(S)-2-hydroxypropylphosphonic acid + 2 NADH + O2 = cis-(1R,2S)-epoxypropylphosphonic acid + 2 H2O + 2 NAD+
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H+ + NADH = H2 + NAD+
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NADH + H+ + reduced ferredoxin = H2 + NAD+ + oxidized ferredoxin
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FMNH2 + NADH + H+ + O2 + alloxan = 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + NAD+ + dialuric acid
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terephthalate + NADH + O2 + H+ = (1R,2S)-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate + NAD+
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nitric oxide + O2 + NADH = nitrate + NAD+ + H+
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9H-carbazole + NADH + H+ + O2 = 2'-aminobiphenyl-2,3-diol + NAD+
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phthalate + NADH + H+ + O2 = cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
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4-sulfobenzoate + NADH + O2 = 3,4-dihydroxybenzoate + sulfite + NAD+
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2,6-dihydroxypyridine + NADH + O2 = 2,3,6-trihydroxypyridine + NAD+ + H2O
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urate + NADH + H+ + O2 = 5-hydroxyisourate + NAD+ + H2O
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6-hydroxynicotinate + NADH + H+ + O2 = 2,5-dihydroxypyridine + NAD+ + H2O + CO2
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pyrrole-2-carboxylate + NADH + H+ + O2 = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O
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1-hydroxy-2-naphthoate + NADH + O2 = 1,2-dihydroxynaphthalene + NAD+ + H2O + CO2
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4-(6-hydroxypyridin-3-yl)-4-oxobutanoate + 2 NADH + 2 H+ + O2 = 2,5-dihydroxypyridine + succinate semialdehyde + 2 NAD+ + H2O
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salicylate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O
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2-heptyl-4(1H)-quinolone + NADH + H+ + O2 = 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD+ + H2O
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taxifolin + NADH + O2 = 2,3-dihydrogossypetin + NAD+ + H2O
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L-ornithine + NADH + H+ + O2 = N5-hydroxy-L-ornithine + NAD+ + H2O
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2-hydroxybenzoyl-CoA + NADH + H+ + O2 = gentisyl-CoA + NAD+ + H2O
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1,3,7-trimethylurate + NADH + H+ + O2 = 1,3,7-trimethyl-5-hydroxyisourate + NAD+ + H2O
show the reaction diagram
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protoasukamycin + NADH + H+ + O2 = 4-hydroxyprotoasukamycin + NAD+ + H2O
show the reaction diagram
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5-methylphenazine-1-carboxylate + NADH + O2 = pyocyanin + NAD+ + CO2 + H2O
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resorcinol + NADH + H+ + O2 = hydroxyquinol + NAD+ + H2O
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aurachin C + NADH + O2 = 4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide + NAD+ + H2O
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3-hydroxybenzoate + NADH + O2 = 3,4-dihydroxybenzoate + NAD+ + H2O
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butane + NADH + H+ + O2 = butan-1-ol + NAD+ + H2O
show the reaction diagram
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L-carnitine + NADH + H+ + O2 = (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NAD+ + H2O
show the reaction diagram
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3-(2-hydroxyphenyl)propanoate + NADH + O2 = 3-(2,3-dihydroxyphenyl)propanoate + NAD+ + H2O
show the reaction diagram
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2-hydroxybiphenyl + NADH + O2 = 2,3-dihydroxybiphenyl + NAD+ + H2O
show the reaction diagram
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4-imidazoleacetate + NADH + O2 = 5-hydroxy-4-imidazoleacetate + NAD+ + H2O
show the reaction diagram
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L-lysine + NADH + H+ + O2 = N6-hydroxy-L-lysine + NAD+ + H2O
show the reaction diagram
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orcinol + NADH + O2 = 2,3,5-trihydroxytoluene + NAD+ + H2O
show the reaction diagram
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3-Hydroxyphenylacetate + NADH + O2 = 2,5-Dihydroxyphenylacetate + NAD+
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phenol + NADH + H+ + O2 = catechol + NAD+ + H2O
show the reaction diagram
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N,N-dimethylaniline + NADH + H+ + O2 = N,N-dimethylaniline N-oxide + NAD+ + H2O
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L-kynurenine + NADH + H+ + O2 = 3-hydroxy-L-kynurenine + NAD+ + H2O
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styrene + NADH + H+ + O2 = styrene epoxide + NAD+ + H2O
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styrene + NADH + H+ + O2 = styrene oxide + NAD+ + H2O
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heme + 2 NADH + 2 H+ + 2 O2 = biliverdin + Fe2+ + CO + 2 NAD+ + H2O
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CMP-N-acetylneuraminate + NADH + O2 = CMP-N-glycoloylneuraminate + NAD+ + H2O
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4-methoxybenzoate + NADH + O2 = 4-hydroxybenzoate + NAD+ + H2O + formaldehyde
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kynurenate + NADH + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + NAD+
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4,9(11)-pregnadiene-3,20-dione + NADH + O2 = 9,11alpha-epoxypregn-4-ene-3,20-dione + NAD+ + H2O
show the reaction diagram
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2-hydroxypyridine + NADH + O2 = 2,5-dihydroxypyridine + NAD+ + H2O
show the reaction diagram
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[eIF5A]-deoxyhypusine + NADH + H+ + O2 = [eIF5A]-hypusine + NAD+ + H2O
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FMNH2 + NADH + H+ + O2 = 5,6-dimethylbenzimidazole + D-erythrose 4-phosphate + NAD+ + ?
show the reaction diagram
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transferrin[Fe(III)]2 + NADH = transferrin[Fe(II)]2 + NAD+
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NADH + aquacob(III)alamin = NAD+ + cob(II)alamin
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NADH + cob(II)alamine = NAD+ + cob(I)alamin
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CO2 + NADH = formate + NAD+
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NADH + oxidized rubredoxin = NAD+ + reduced rubredoxin
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2 oxidized rubredoxin + NADH = 2 reduced rubredoxin + NAD+ + H+
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beta-ketoacyl-[acyl-carrier protein] + NADH + H+ = beta-hydroxyacyl-[acyl-carrier protein] + NAD+
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chanoclavine-I aldehyde + NADH + H+ = dihydrochanoclavine-I aldehyde + NAD+
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4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADH + H+ = 4-hydroxy-2,5-dimethyl-3(2H)-furanone + NAD+
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cobalt-precorrin-6A + NADH + H+ = cobalt-precorrin-6B + NAD+
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(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA + 2 NADH + 2 oxidized ferredoxin iron-sulfur cluster = 3-(3,4-dihydroxyphenyl)propanoyl-CoA + 2 NAD+ + 2 reduced ferredoxin iron-sulfur cluster
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2-coumarate + NADH = melilotate + NAD+
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protochlorophyllide + NADH + H+ = chlorophyllide a + NAD+
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xanthommatin + NADH = 5,12-dihydroxanthommatin + NAD+
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crotonyl-CoA + NADH = butanoyl-CoA + NAD+
show the reaction diagram
5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + NADH = 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline + NAD+
show the reaction diagram
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(6E)-10-oxogeranial + NADH + H+ = cis-trans-nepetalactol + NAD+
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(3E)-3-[(4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NADH + H+ = 3-[(1R,4S)-4-hydroxycyclohex-2-en-1-yl]-2-oxopropanoate + NAD+
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crotonyl-CoA + 2 NADH + 2 Fd- = butyryl-CoA + 2 NAD+ + 2 Fd2-
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glyoxylate + NH3 + NADH = glycine + H2O + NAD+
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(indol-3-yl)pyruvate + NH3 + NADH + H+ = L-tryptophan + NAD+ + H2O
show the reaction diagram
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2-oxoglutarate + NH3 + NADH = L-glutamate + H2O + NAD+
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phenylpyruvate + NH3 + NADH = L-phenylalanine + H2O + NAD+
show the reaction diagram
oxaloacetate + NH4+ + NADH = L-aspartate + NAD+ + H2O
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L-arginine + pyruvate + NADH + H+ = N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O
show the reaction diagram
L-5,10-methenyl-tetrahydrofolate + NADH = L-5,10-methylenetetrahydrofolate + NAD+
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DELTA1-pyrroline-5-carboxylate + NADH + H+ = L-proline + NAD+
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glycine + pyruvate + NADH + H+ = N-(carboxymethyl)-D-alanine + NAD+ + H2O
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taurine + NADH + H+ + pyruvate = tauropine + NAD+ + H2O
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beta-alanine + pyruvate + NADH = beta-alanopine + NAD+ + H2O
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amino acid + pyruvate + NADH + H+ = opine + NAD+ + H2O
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7,8-dihydrofolate + NADH + H+ = 5,6,7,8-tetrahydrofolate + NAD+
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FMN + NADH + H+ = FMNH2 + NAD+
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FAD + NADH + H+ = FADH2 + NAD+
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FMN + NADH + H+ = FMNH2 + NAD+
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DELTA1-pyrroline-2-carboxylate + NADH + H+ = L-proline + NAD+
show the reaction diagram
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2-oxoglutarate + L-2,3-diaminopropanoate + NADH + H+ = N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate + NAD+ + H2O
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L-lysine + 2-oxoglutarate + NADH + H+ = N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O
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NADH + NADP+ = NADPH + NAD+
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NADH + H+ + ferrileghemoglobin = NAD+ + ferroleghemoglobin
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NADH + H+ + O2 = NAD+ + H2O2
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nitrite + NADH + H+ = ammonia + NAD+ + H2O
show the reaction diagram
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2,4,6-trinitrotoluene + NADH + H+ = 4-hydroxyamino-2,6-dinitrotoluene + NAD+ + H2O
show the reaction diagram
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trimethylamine N-oxide + NADH = NAD+ + trimethylamine + H2O
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asparagusate + NADH = dihydroasparagusate + NAD+
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CoA-disulfide + NADH + H+ = CoA + NAD+
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4,4'-disulfanediyldibutanoate + NADH + H+ = 4-mercaptobutyric acid + NAD+
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thioredoxin disulfide + NADH + H+ = thioredoxin + NAD+
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acetyl-CoA + malonyl-CoA + NADH + NADPH = ?
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ATP + NADH = ADP + NADPH
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NADH + H2O = NMNH + AMP
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NADH + H2O = NMNH + AMP
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1091 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-threonine + NAD+ = (2S)-2-amino-3-oxobutanoate + NADH + H+
show the reaction diagram
(R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH
show the reaction diagram
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pyridoxal + NAD+ = 4-pyridoxolactone + NADH + H+
show the reaction diagram
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indolelactate + NAD+ = indolepyruvate + NADH
show the reaction diagram
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D-apiitol + NAD+ = D-apiose + NADH
show the reaction diagram
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D-glucose + NAD+ = D-glucono-1,5-lactone + NADH + H+
show the reaction diagram
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L-arabinitol + NAD+ = L-xylulose + NADH + H+
show the reaction diagram
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D-aldose + NAD+ = D-aldonolactone + NADH
show the reaction diagram
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2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH
show the reaction diagram
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2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADH + H+
show the reaction diagram
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2-dehydro-3-deoxy-D-gluconate + NAD+ = (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH
show the reaction diagram
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L-threonate + NAD+ = 3-dehydro-L-threonate + NADH
show the reaction diagram
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L-arabinitol + NAD+ = L-ribulose + NADH + H+
show the reaction diagram
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D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+
show the reaction diagram
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5-O-methyl-myo-inositol + NAD+ = 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADH
show the reaction diagram
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perillyl alcohol + NAD+ = perillyl aldehyde + NADH
show the reaction diagram
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3alpha-hydroxy-5beta-androstane-17-one + NAD+ = 5beta-androstane-3,17-dione + NADH
show the reaction diagram
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cyclopentanol + NAD+ = cyclopentanone + NADH
show the reaction diagram
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2-butyne-1,4-diol + NAD+ = 4-hydroxybut-2-ynal + NADH
show the reaction diagram
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(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+ = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH
show the reaction diagram
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hydroxymalonate + NAD+ = oxomalonate + NADH
show the reaction diagram
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(R)-pantoate + NAD+ = 2-dehydropantoate + NADH + H+
show the reaction diagram
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L-rhamnose + NAD+ = L-rhamno-1,4-lactone + NADH
show the reaction diagram
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cholate + NAD+ = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + NADH + H+
show the reaction diagram
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2-methyl-3-hydroxybutyryl-CoA + NAD+ = 2-methylacetoacetyl-CoA + NADH
show the reaction diagram
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cholest-5-ene-3beta,7alpha-diol + NAD+ = 7alpha-hydroxycholest-4-en-3-one + NADH
show the reaction diagram
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geraniol + NAD+ = geranial + NADH
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cinnamyl alcohol + NAD+ = cinnamaldehyde + NADH + H+
show the reaction diagram
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sorbitol + NAD+ = D-fructose + NADH + H+
show the reaction diagram
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a long-chain (S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+
show the reaction diagram
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morphine + NAD+ = morphinone + NADH + H+
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vomifoliol + NAD+ = dehydrovomifoliol + NADH
show the reaction diagram
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trans-4-hydroxycyclohexanecarboxylate + NAD+ = 4-oxocyclohexanecarboxylate + NADH
show the reaction diagram
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(+)-cis-sabinol + NAD+ = (+)-sabinone + NADH
show the reaction diagram
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N-acetyl-D-mannosamine + NAD+ = N-acetyl-D-mannosaminolactone + NADH + H+
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3-(4-hydroxyphenyl)lactate + NAD+ = 4-hydroxyphenylpyruvate + NADH
show the reaction diagram
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N-acetyl-D-glucosamine + NAD+ = N-acetyl-D-glucosaminate + NADH
show the reaction diagram
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(4R,6S)-trans-carveol + NAD+ = (4R)-carvone + NADH
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cyclohexanol + NAD+ = cyclohexanone + NADH
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Galactitol-1-phosphate + NAD+ = L-Tagatose 6-phosphate + NADH
show the reaction diagram
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6-hydroxyhexanoate + NAD+ = 6-oxohexanoate + NADH
show the reaction diagram
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3-hydroxypimeloyl-CoA + NAD+ = 3-oxopimeloyl-CoA + NADH
show the reaction diagram
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sn-glycerol-1-phosphate + NAD+ = dihydroxyacetone phosphate + NADH
show the reaction diagram
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