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Information on EC 1.14.20.14 - hapalindole-type alkaloid chlorinase

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IUBMB Comments
The enzyme, characterized from hapalindole-type alkaloids-producing cyanobacteria, is a specialized iron(II)/2-oxoglutarate-dependent oxygenase that catalyses the chlorination of its substrates in a reaction that requires oxygen, chloride ions, iron(II) and 2-oxoglutarate.
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The enzyme appears in viruses and cellular organisms
Synonyms
ambO5, AmbO5 protein, welO5, WelO5 protein, WelO5*, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
12-epi-fischerindole U + 2-oxoglutarate + O2 + chloride = 12-epi-fischerindole G + succinate + CO2 + H2O
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(2)
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hapalindole U + 2-oxoglutarate + O2 + chloride = hapalindole G + succinate + CO2 + H2O
show the reaction diagram
(1)
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PATHWAY SOURCE
PATHWAYS
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