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Information on EC 1.1.1.95 - phosphoglycerate dehydrogenase

for references in articles please use BRENDA:EC1.1.1.95
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IUBMB Comments
This enzyme catalyses the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis. The reaction occurs predominantly in the direction of reduction. The enzyme from the bacterium Escherichia coli also catalyses the activity of EC 1.1.1.399, 2-oxoglutarate reductase .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
phgdh, 3-phosphoglycerate dehydrogenase, d-3-phosphoglycerate dehydrogenase, 3-pgdh, 3pgdh, ehpgdh, d-phosphoglycerate dehydrogenase, pgdh1, phosphoglycerate oxidoreductase, phosphoglyceric acid dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3-phospho-D-glycerate + NAD+ = 3-phosphooxypyruvate + NADH + H+
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