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6.2.1.2: medium-chain acyl-CoA ligase

This is an abbreviated version!
For detailed information about medium-chain acyl-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.2

Reaction

ATP
+
a medium-chain fatty acid
+
CoA
=
AMP
+
diphosphate
+
a medium-chain acyl-CoA

Synonyms

Acyl-activating enzyme, butanoate:CoA ligase (AMP-forming), butyrate-CoA ligase, Butyryl-CoA synthetase, Butyryl-coenzyme A synthetase, EloA, elongase, Fatty acid thiokinase (medium chain), L-(+)-3-Hydroxybutyryl CoA ligase, Macs, MACS2, medium chain acyl-CoA synthase, medium chain acyl-CoA synthetase, Medium chain acyl-coenzyme A synthetase, medium-chain acyl coenzyme A synthetase, medium-chain acyl-CoA synthetase 2, Mig protein, More, Short-chain acyl-CoA synthetase, Synthetase, butyryl conzyme A, xenobiotic/medium-chain fatty acid:CoA ligase, XM-ligase

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.2 medium-chain acyl-CoA ligase

General Stability

General Stability on EC 6.2.1.2 - medium-chain acyl-CoA ligase

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GENERAL STABILITY
ORGANISM
UNIPROT
LITERATURE
presence of 200 mM NaCl is essential for the stability of the enzyme and storage or conversions in buffer lacking NaCl resulted in rapid loss of activity