6.2.1.2: medium-chain acyl-CoA ligase

This is an abbreviated version!
For detailed information about medium-chain acyl-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.2

6.2.1.2

desaturase

polyunsaturated

pufas

docosahexaenoic

arachidonic

monounsaturated

eicosapentaenoic

linoleic

desaturation

elovl5

unsaturated

lc-pufas

acyl-coas

oleic

stearoyl-coa

very-long-chain

vlcfas

palmitoleic

delta6

stearic

alpha-linolenic

linseed

gamma-linolenic

alpina

stargardt

mortierella

isochrysis

3-ketoacyl-coa

erucic

cis-vaccenic

vaccenic

dihomo-gamma-linolenic

medicine

stearidonic

Reaction

Synonyms

Acyl-activating enzyme, butanoate:CoA ligase (AMP-forming), butyrate-CoA ligase, Butyryl-CoA synthetase, Butyryl-coenzyme A synthetase, EloA, elongase, Fatty acid thiokinase (medium chain), L-(+)-3-Hydroxybutyryl CoA ligase, Macs, MACS2, medium chain acyl-CoA synthase, medium chain acyl-CoA synthetase, Medium chain acyl-coenzyme A synthetase, medium-chain acyl coenzyme A synthetase, medium-chain acyl-CoA synthetase 2, Mig protein, More, Short-chain acyl-CoA synthetase, Synthetase, butyryl conzyme A, xenobiotic/medium-chain fatty acid:CoA ligase, XM-ligase

ECTree

6 Ligases

6.2 Forming carbon-sulfur bonds

6.2.1 Acid-thiol ligases

6.2.1.2 medium-chain acyl-CoA ligase

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Results	in table
4	Activating Compound
165	AA Sequence
1	Application
1	CAS Registry Number
6	Cloned(Commentary)
1	Cofactor
105	Disease/ Diagnostics
1	General Stability
1	IC50 Value
57	Inhibitors
3	kcat/KM [mM/s]
13	Ki Value [mM]
39	KM Value [mM]
16	Localization
15	Metals/Ions
15	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
33	Organism
14	Pathway
13	PDB ID
9	pH Optimum
2	pH Range
1	pH Stability
6	Protein Variants
17	Purification (Commentary)
3	Reaction
1	Reaction Type
32	Reference
32	Source Tissue
10	Specific Activity [micromol/min/mg]
1	Storage Stability
154	Substrates and Products (Substrate)
11	Subunits
30	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
10	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 6.2.1.2 - medium-chain acyl-CoA ligase

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130000

Bos taurus

dimeric form of enzyme, gel filtration

676

142000

Pseudomonas aeruginosa

disc gel electrophoresis

669

145000

Paecilomyces variotii

gel filtration

668

260000

Bos taurus

tetrameric form of enzyme, gel filtration

676

37000

Pseudomonas aeruginosa

4 * 37000, SDS-PAGE

669

38000

Bos taurus

x * 38000, SDS-PAGE

672

41000

2 entries

46500

Sus scrofa

gel filtration

650950

62600

Penicillium chrysogenum

O74725

x * 62600, recombinant enzyme, SDS-PAGE

690837

64000

Bos taurus

monomeric form of enzyme, gel filtration

676

65000

3 entries

74000

Paecilomyces variotii

2 * 74000, SDS-PAGE

668