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6.2.1.2: medium-chain acyl-CoA ligase

This is an abbreviated version!
For detailed information about medium-chain acyl-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.2

Reaction

ATP
+
a medium-chain fatty acid
 +
CoA
=
AMP
 +
diphosphate
 +
a medium-chain acyl-CoA

Synonyms

Acyl-activating enzyme, butanoate:CoA ligase (AMP-forming), butyrate-CoA ligase, Butyryl-CoA synthetase, Butyryl-coenzyme A synthetase, EloA, elongase, Fatty acid thiokinase (medium chain), L-(+)-3-Hydroxybutyryl CoA ligase, Macs, MACS2, medium chain acyl-CoA synthase, medium chain acyl-CoA synthetase, Medium chain acyl-coenzyme A synthetase, medium-chain acyl coenzyme A synthetase, medium-chain acyl-CoA synthetase 2, Mig protein, More, Short-chain acyl-CoA synthetase, Synthetase, butyryl conzyme A, xenobiotic/medium-chain fatty acid:CoA ligase, XM-ligase

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.2 medium-chain acyl-CoA ligase

Specific Activity

Specific Activity on EC 6.2.1.2 - medium-chain acyl-CoA ligase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.02
purified recombinant enzyme
0.023
-
cell extract, with 0.001 mM hexanoic acid as a substrate in 0.2 M Tris-HCl buffer (pH 8.5)
3.3
-
-
3.718
-
-
4.14
-
after 180fold purification, with 0.001 mM hexanoic acid as a substrate in 0.2 M Tris-HCl buffer (pH 8.5)
4.15
-
-
additional information