Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

4.6.1.20: ribonuclease U2

This is an abbreviated version!
For detailed information about ribonuclease U2, go to the full flat file.

Word Map on EC 4.6.1.20

Reaction

an [RNA fragment]-3'-adenosine-2',3'-cyclophosphate
+
H2O
=
an [RNA fragment]-3'-adenosine -3'-phosphate

Synonyms

EC 3.1.27.4, Pleospora RNase, Purine specific endoribonuclease, Purine-specific ribonuclease, Purine-specific RNase, Ribonuclease (purine), ribonuclease U2, ribonuclease U2A, ribonuclease U2B, Ribonuclease U3, RNase U2, RNase U2A, RNase U3, Trichoderma koningi RNase III, YoeB

ECTree

     4 Lyases
         4.6 Phosphorus-oxygen lyases
             4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
                4.6.1.20 ribonuclease U2

Engineering

Engineering on EC 4.6.1.20 - ribonuclease U2

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
H83Q
-
no enzymic activity
R65A
-
no enzymic activity
Y84A
-
no enzymic activity
Y84F
-
reduced enzymic activity
C1S/C54S
lacking one disulfide bridge, 60% of wild-type activity
E49A
mutant with non-specific ribonuclease activity and a tendency to undercut RNA
H101Q
devoid of detectable activity