3.4.23.15: renin
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For detailed information about renin, go to the full flat file.
Word Map on EC 3.4.23.15
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3.4.23.15
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hypertension
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aldosterone
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arterial
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urinary
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cardiovascular
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cardiac
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antihypertensive
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normotensive
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gastric
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glomerular
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natriuretic
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hemodynamic
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systolic
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diastolic
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sympathetic
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ras
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angiotensin-converting
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norepinephrine
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output
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adrenal
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blocker
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prostaglandin
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ventricular
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catecholamine
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diuretic
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creatinine
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hg
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electrolyte
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placebo
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vasopressin
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captopril
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vasodilator
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cortisol
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supine
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intrarenal
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renovascular
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conscious
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pressor
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posture
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acth
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noradrenaline
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losartan
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hypotensive
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mineralocorticoid
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vasoconstriction
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enalapril
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furosemide
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anp
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medicine
-
macula
-
pharmacology
-
aceis
-
diagnostics
- 3.4.23.15
- hypertension
- aldosterone
- arterial
- urinary
- cardiovascular
- cardiac
-
antihypertensive
-
normotensive
- gastric
- glomerular
-
natriuretic
-
hemodynamic
-
systolic
-
diastolic
-
sympathetic
- ras
-
angiotensin-converting
- norepinephrine
- output
- adrenal
-
blocker
- prostaglandin
- ventricular
- catecholamine
-
diuretic
- creatinine
- hg
-
electrolyte
-
placebo
- vasopressin
- captopril
-
vasodilator
- cortisol
-
supine
-
intrarenal
-
renovascular
-
conscious
-
pressor
-
posture
- acth
- noradrenaline
- losartan
-
hypotensive
-
mineralocorticoid
-
vasoconstriction
- enalapril
- furosemide
- anp
- medicine
-
macula
- pharmacology
-
aceis
- diagnostics
Reaction
cleavage of Leu-/- bond in angiotensinogen to generate angiotensin I =
Synonyms
angiotensin-forming enzyme, angiotensinogenase, EC 3.4.4.15, EC 3.4.99.19, prorenin, REN, SVAP, SVAP A1, SVAP B1, SVAP B2, venom aspartic protease
ECTree
3.4.23.15 reninAdvanced search results
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results (Expression
Expression on EC 3.4.23.15 - renin
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EXPRESSION 
ORGANISM
UNIPROT
LITERATURE
after 5 weeks of renal artery stenosis, plasma renin activity is 3fold greater than in sham-operated rabbits
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angiotensin II inhibits renin release from the juxtaglomerular cells in the kidney
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chronic sympatho-inhibition with rilmenidine (2.5 mg/kg/day) reduces basal plasma renin activity
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diuretics increase plasma renin concentration and plasma renin activity, as volume depletion stimulates the release of renin from the kidney
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renin inhibitors like aliskiren increase the plasma concentration of renin because they attenuate the negative feedback effect of angiotensin II on renin release
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renin release from juxtaglomerular cells is inhibited by Ca2+ and calcium-dependent phosphodiesterase 1C
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renin-angiotensin-aldosterone system blockade with angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers leads to exacerbated renin release through loss of negative-feedback inhibition
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the angiotensin type I receptor 1166C allele in homozygous form is characterized by low plasma renin levels
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the enzyme exhibits low mRNA expression levels in all stages of pre-adipocyte differentiation with no significant transcriptional increase up to day 21
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there are no significant differences in mRNA abundance between salinities or time for the enzyme gene
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there is an increase of renin activity in the kidney of TGM(rTon) mice when compared to control animals
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treatment with 0.05 mg urocortin 2 or 0.05 mg urocortin 2 plus 20 mg furosemide markedly reduces plasma renin activity
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treatment with 16 mg azelnidipine for 4 weeks does not affect plasma renin activity
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tubular renin protein is increased by angiotensin II (400 ng/kg/min infusion for 12 days) and angiotensin-converting enzyme inhibitor (lisinopril, 100 mg/l), but not by the combination of angiotensin II plus angiotensin-converting enzyme inhibitor
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