3.4.23.15: renin

This is an abbreviated version!
For detailed information about renin, go to the full flat file.

cleavage of Leu-/- bond in angiotensinogen to generate angiotensin I =

angiotensin-forming enzyme, angiotensinogenase, EC 3.4.4.15, EC 3.4.99.19, prorenin, REN, SVAP, SVAP A1, SVAP B1, SVAP B2, venom aspartic protease

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Results	in table
1	Activating Compound
205	AA Sequence
26	Application
1	CAS Registry Number
23	Cloned(Commentary)
9	Crystallization (Commentary)
38807	Disease/ Diagnostics
17	Expression
6	General Information
8	General Stability
283	IC50 Value
452	Inhibitors
3	kcat/KM [mM/s]
38	Ki Value [mM]
21	KM Value [mM]
15	Localization
41	Molecular Weight [Da]
65	Natural Substrates/ Products (Substrates)
171	Organism
191	PDB ID
17	pH Optimum
3	pH Range
1	pH Stability
23	Posttranslational Modification
6	Protein Variants
30	Purification (Commentary)
2	Reaction
1	Reaction Type
171	Reference
123	Source Tissue
40	Specific Activity [micromol/min/mg]
12	Storage Stability
111	Substrates and Products (Substrate)
12	Subunits
15	Synonyms
3	Temperature Optimum [°C]
8	Turnover Number [1/s]

KCat KM Value on EC 3.4.23.15 - renin

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250

angiotensinogen

at pH 7.4 and 37°C

6400

recombinant ovine angiotensinogen from CHO cells

at pH 7.2 and 37°C

8300

recombinant ovine angiotensinogen from Escherichia coli

at pH 7.2 and 37°C