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3.4.21.76: Myeloblastin

This is an abbreviated version!
For detailed information about Myeloblastin, go to the full flat file.

Word Map on EC 3.4.21.76

Reaction

Hydrolysis of proteins, including elastin, by preferential cleavage: -Ala-/- > -Val-/- =

Synonyms

AGP7, C-ANCA antigen, hPR-3, human leukocyte proteinase 3, human PR3, human proteinase 3, Leukocyte proteinase 3, Leukocyte proteinase 4, membrane proteinase 3, membrane-associated proteinase 3, mP3, mPR3, myeloblastin, neutrophil protease PR3, neutrophil proteinase 3, neutrophil serine protease, neutrophilic serine protease proteinase 3, P29, p29b, PMNL proteinase, Pr 3, PR-3, PR3, protease 3, proteinase 3, Proteinase PR-3, Proteinase-3, proteinase3, PRTN3, SAP3, secreted aspartic proteinase 3, surface proteinase 3, Wegener autoantigen, Wegener's autoantigen, Wegener's granulomatosis autoantigen, Xenopus PR3, xPR-3

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.21 Serine endopeptidases
                3.4.21.76 Myeloblastin

Molecular Weight

Molecular Weight on EC 3.4.21.76 - Myeloblastin

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22000
3 * 29000 + 1 * 22000, SDS-PAGE
29000
30000
32000
-
recombinant mutant N102Q and N147Q, immunoprecipitation
34000
-
recombinant PR3 wild-type, immunoprecipitation
36000
-
recombinant PR3 wild-type, immunoprecipitation
additional information
-
processing of proteinase 3 in U937 human myelomonocytic cell line: a 35000 MW precursor is converted into a 29000 MW mature form