3.4.21.41: complement subcomponent C1r
This is an abbreviated version!
For detailed information about complement subcomponent C1r, go to the full flat file.
Word Map on EC 3.4.21.41
Reaction
Selective cleavage of Lys(or Arg)-/-Ile bond in complement subcomponent C1s to form C_overbar_1s_ (EC 3.4.21.42) =
Synonyms
activated complement C1r, C1r, C1r protease, C1r serine protease, C1r-LP, C1rbar-esterase, complement C1r subcomponent-like protein, complement C1r, activated, complement protease C1r, complement subcomponent 1r, CUB, multiprotein complex C1, proteases C1r, serine protease C1r, Xld, xolloid
ECTree
3.4.21.41 complement subcomponent C1rAdvanced search results
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results (Cloned
Cloned on EC 3.4.21.41 - complement subcomponent C1r
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CLONED (Commentary) 
ORGANISM
UNIPROT
LITERATURE
baculovirus-mediated expression is used to produce fragments containing the SP domain and either 2 CCP modules (CCP1/2-SP) or only the second CCP module (CCP2-SP). In each case the wild-type species and two mutants stabilized in the proenzyme form by mutations at the cleavage site (R446Q) or at the active site serine residue (S637A) are produced
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CUB2-complement control protein 1 module expressed in Escherichia coli BL21(DE3) pLysS
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development and evaluation of a method for expression of recombinant full-length human C-terminally tagged C1q involving stable transfection of HEK 293-F mammalian cells
expression of complement control protein module 2 (I356-V433), complement control protein module 1 - complement control protein module 2 (I289-V433), CUB2 - complement control protein module 1 (Q173-D358) and CUB2 - complement control protein module 1 - complement control protein module 2 (Q173-V433)
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expression of modules: Q173-D358 (CUB2-complement control protein 1) and I356-V433 (complement control protein 2)
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expression of the isolated active catalytic region, containing the C-terminal serine protease domain, and two preceding complement control protein modules, of C1r in Escherichia coli strain BL21(DE3)
production of the CCP1-CCP2-SP, the CCP2-SP and the SP fragments in Escherichia coli
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recombinant expression of full-length C1r protease and the CUB1-EGF-CUB2 fragment with low yield
