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Literature summary for 3.4.21.41 extracted from

  • Nilojan, J.; Bathige, S.D.N.K.; Kugapreethan, R.; Yang, H.; Kim, M.J.; Nam, B.H.; Lee, J.
    Molecular features and the transcriptional and functional delineation of complement system activators C1r and C1s from Sebastes schlegelii (2018), Dev. Comp. Immunol., 81, 279-290 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 cells Sebastes schlegelii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
complement component C1s + H2O Sebastes schlegelii
-
activated complement component C1s + ?
-
?

Organism

Organism UniProt Comment Textmining
Sebastes schlegelii A0A2I6BQJ9 black rockfish
-

Purification (Commentary)

Purification (Comment) Organism
maltose affinity column chromatography Sebastes schlegelii

Source Tissue

Source Tissue Comment Organism Textmining
gill high expression Sebastes schlegelii
-
liver highest expression Sebastes schlegelii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
complement component C1s + H2O
-
Sebastes schlegelii activated complement component C1s + ?
-
?
succinylated casein + H2O
-
Sebastes schlegelii ?
-
?

Subunits

Subunits Comment Organism
? x * 69500, enzyme fused to maltose binding protein, SDS-PAGE Sebastes schlegelii
? x * 75900, calculated from amino acid sequence Sebastes schlegelii

Synonyms

Synonyms Comment Organism
C1r
-
Sebastes schlegelii

pI Value

Organism Comment pI Value Maximum pI Value
Sebastes schlegelii calculated from amino acid sequence
-
5.1

Expression

Organism Comment Expression
Sebastes schlegelii the enzyme mRNA expression is significantly upregulated in spleen and liver after pathologic stress with Streptococcus iniae up