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3.2.1.51: alpha-L-fucosidase

This is an abbreviated version!
For detailed information about alpha-L-fucosidase, go to the full flat file.

Word Map on EC 3.2.1.51

Reaction

an alpha-L-fucoside
+
H2O
=
L-fucose
 +
an alcohol

Synonyms

acid hydrolase, Afc2, Afc3, AFU, Alf1_Wf, alfA, alfB, alfC, alpha-fuc, alpha-fucosidase, alpha-L fucosidase, alpha-L-fucosidase, alpha-L-fucosidase 1, alpha-L-fucosidase 2, alpha-L-fucosidase I, alpha-L-fucosidase iso2, alpha-L-fucosidase isoenzyme 1, Alpha-L-fucoside fucohydrolase, alpha-L-fucoside fucohydrolase 2, alphafuc, bfo_2737, BgFUC, Eo0918, Eo3066, Eo3812, FpFucA, FucA, Fuca1, Fuca2, Fuca3, FucFA, fucosidase, alpha-L-1, tissue, h-Fuc, mfuc1, mfuc2, mfuc3, mfuc4, mfuc5, mfuc6, mfuc7, Pap-Alf, serum AFU, serum alpha-L-fucosidase, TfFuc1, TMalphafuc

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.51 alpha-L-fucosidase

Activating Compound

Activating Compound on EC 3.2.1.51 - alpha-L-fucosidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
1 mM, 1.2fold activation
azide
increases the rate of substrate cleavage in depending of azide concentration
bovine serum albumin
-
chemokine CCL1
-
1.8-fold increase of ALP-expression after 24-h stimulation
-
chemokine CCL5
-
2.2-fold increase of ALP-expression after 24-h stimulation
-
CN-
-
30% activation at 10 mM
dithiothreitol
-
13% activation at 0.2 mM
ethylenediaminetetraacetic acid
-
5% activation at 10 mM
formate
increases the rate of substrate cleavage in depending of azide concentration
KCl
-
17% activation at 300 mM
methanol
linear increase in enzyme-catalyzed cleavage of p-nitrophenyl alpha-L-fucoside and fucosyl fluoride
NaCl
small positive effect
Sodium azide
1M, enhanced enzyme activity, only in mutants
additional information
-