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3.2.1.51: alpha-L-fucosidase

This is an abbreviated version!
For detailed information about alpha-L-fucosidase, go to the full flat file.

Word Map on EC 3.2.1.51

Reaction

an alpha-L-fucoside
+
H2O
=
L-fucose
+
an alcohol

Synonyms

acid hydrolase, Afc2, Afc3, AFU, Alf1_Wf, alfA, alfB, alfC, alpha-fuc, alpha-fucosidase, alpha-L fucosidase, alpha-L-fucosidase, alpha-L-fucosidase 1, alpha-L-fucosidase 2, alpha-L-fucosidase I, alpha-L-fucosidase iso2, alpha-L-fucosidase isoenzyme 1, Alpha-L-fucoside fucohydrolase, alpha-L-fucoside fucohydrolase 2, alphafuc, bfo_2737, BgFUC, Eo0918, Eo3066, Eo3812, FpFucA, FucA, Fuca1, Fuca2, Fuca3, FucFA, fucosidase, alpha-L-1, tissue, h-Fuc, mfuc1, mfuc2, mfuc3, mfuc4, mfuc5, mfuc6, mfuc7, Pap-Alf, serum AFU, serum alpha-L-fucosidase, TfFuc1, TMalphafuc

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.51 alpha-L-fucosidase

pH Range

pH Range on EC 3.2.1.51 - alpha-L-fucosidase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3 - 5
3.5 - 6.3
-
pH 3.5: about 55% of maximal activity, pH 6.25: 50% of maximal activity
3.7 - 5.5
less than 50% of maximal activity above and below
4 - 6.5
pH 4.0: about 60% of maximal activity, pH 6.5: about 70% of maximal activity
4 - 7
-
pH 4.0: about 50% of maximal activity, pH 7.0: about 65% of maximal activity
4.5 - 6
-
optimal activity within
4.8 - 5.2
recombinant enzyme
5.5 - 7
5.5 - 7.5
-
high activity between
5.5 - 8.5
pH 5.5: about 40% of maximal activity, pH 8.5: about 35% of maximal activity
6 - 6.5
enzyme in active form
6 - 8.5
-
pH 6.0: about 30% of maximal activity, pH 8.5: about 50% of maximal activity
6.5 - 8.8
-
pH 6.5: about 50% of maximal activity, pH 8.8: about 55% of maximal activity
additional information
-
alpha-fucosidase from the uninfected semen displays a broad acidic pH range of 4.5–5.5 and a subsequent neutral optimum of pH 6.8–7.2. There is an absence of the neutral pH optimum for the pathological semen