3.1.1.8: cholinesterase

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For detailed information about cholinesterase, go to the full flat file.

Reaction

Synonyms

acyl choline acylhydrolase, acylcholine acyl-hydrolase, Acylcholine acylhydrolase, atypical cholinesterase, BChE, benzoylcholinesterase, BoBChE, BTCh, BTChI-ChE, BtChoEase, BuChE, butyrocholinesterase, butyryl-ChE, butyrylChE, butyrylcholine esterase, butyrylcholine-hydrolyzing enzyme, butyrylcholinesterase, butyrylcholinesterase K, calcium-activated butyrylcholinesterase, ChE, ChE-II, CholE, choline esterase, choline esterase II (unspecific), cholinesterase, dBChE, DjChE, Djche1, Djche2, EQ-BCHE, eqBChE, EqBuChE, esterase, butyrylcholine, esterase, choline, hBChE, HuBChE, mBuChE I, mBuChE II, monomeric butyrylcholinesterase I, monomeric butyrylcholinesterase II, More, non specific cholinesterase, non-specific cholinesterase, PChE, planarian cholinesterase, plasma cholinesterase, plasma esterase, plasmatic cholinesterase, PoBChE, propionylcholinesterase, pseudo choline esterase, pseudo cholinesterase, pseudocholinesterase, PTChI-ChE, rBChE, serum cholinesterase

ECTree

     3 Hydrolases

         3.1 Acting on ester bonds

             3.1.1 Carboxylic-ester hydrolases

                3.1.1.8 cholinesterase

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Results	in table
26	Activating Compound
30	AA Sequence
17	Application
1	CAS Registry Number
28	Cloned(Commentary)
8	Crystallization (Commentary)
13920	Disease/ Diagnostics
4	Expression
25	General Information
4	General Stability
605	IC50 Value
1641	Inhibitors
18	kcat/KM [mM/s]
215	Ki Value [mM]
228	KM Value [mM]
50	Localization
4	Metals/Ions
33	Molecular Weight [Da]
135	Natural Substrates/ Products (Substrates)
309	Organism
102	PDB ID
95	pH Optimum
9	pH Range
4	pH Stability
10	Posttranslational Modification
87	Protein Variants
41	Purification (Commentary)
15	Reaction
1	Reaction Type
309	Reference
328	Source Tissue
80	Specific Activity [micromol/min/mg]
18	Storage Stability
555	Substrates and Products (Substrate)
37	Subunits
427	Synonyms
1	Systematic Name
80	Temperature Optimum [°C]
1	Temperature Range [°C]
19	Temperature Stability [°C]
103	Turnover Number [1/s]

Expression

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Expression on EC 3.1.1.8 - cholinesterase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

hypoxanthine, at 0.01 mM reduces enzyme activity in the serum of 60-day-old rats while trolox and allopurinol, but not ascorbic acid, are able to prevent this reduction in activity

Rattus norvegicus

-

730237

reductions in the activity of cholinesterase occur in acute infection by Trypanosoma evansi in rats

Rattus norvegicus

-

714925

senescence-accelerated mouse-prone/8 mice show double BuChE activity in brain

Mus musculus

-

715985

type 2 diabetics with or without metabolic syndrome have significantly higher activity of butyrylcholinesterase than control group

Homo sapiens

-

713701