1.6.1.2: NAD(P)+ transhydrogenase (Re/Si-specific)

This is an abbreviated version!
For detailed information about NAD(P)+ transhydrogenase (Re/Si-specific), go to the full flat file.

Word Map on EC 1.6.1.2

Reaction

NADPH
+
NAD+
=
NADP+
+
NADH

Synonyms

dII, dIII, energy-linked transhydrogenase, energy-linked, mitochondrial transhydrogenase, H+-thase, mitochondrial transhydrogenase, NAD transhydrogenase, NAD(P) transhydrogenase, NADH transhydrogenase, NADH-NADP-transhydrogenase, NADPH transhydrogenase, NADPH-NAD oxidoreductase, NADPH-NAD transhydrogenase, NADPH:NAD+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, PNT, PntAB, proton-translocating nicotinamide nucleotide transhydrogenase, proton-translocating transhydrogenase, pyridine nucleotide transferase, pyridine nucleotide transhydrogenase, reversible mitochondrial membrane-associated transhydrogenase, transhydrogenase, transhydrogenase, nicotinamide adenine dinucleotide (phosphate)

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.1 With NAD+ or NADP+ as acceptor
                1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)

Engineering

Engineering on EC 1.6.1.2 - NAD(P)+ transhydrogenase (Re/Si-specific)

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A1008P
-
the mutation is associated with familial glucocorticoid deficiency
A533V
-
the mutation is associated with familial glucocorticoid deficiency
A553V
-
the mutation is associated with familial glucocorticoid deficiency
D277Y
-
the mutation is associated with left ventricular noncompaction
F215S
G200S
G664R
-
the mutation is associated with familial glucocorticoid deficiency
G678A
-
the mutation is associated with familial glucocorticoid deficiency
G678R
-
the mutation is associated with familial glucocorticoid deficiency
G862D
-
the mutation is associated with familial glucocorticoid deficiency
H365P
-
the mutation is associated with familial glucocorticoid deficiency
L977P
-
the mutation is associated with familial glucocorticoid deficiency
N1009K
-
the mutation is associated with familial glucocorticoid deficiency
P437L
-
the mutation is associated with familial glucocorticoid deficiency
S193N
T357A
-
the mutation is associated with familial glucocorticoid deficiency
Y201K
-
the mutation is associated with familial glucocorticoid deficiency
Y388S
-
the mutation is associated with familial glucocorticoid deficiency
E155W
-
dIII domain, displays similar catalytic properties as wild type, introduced tryptophan fluorescence is sensitive to the redox state of the bound nucleotide
Y235F
Y235N
additional information