1.6.1.2: NAD(P)+ transhydrogenase (Re/Si-specific)

This is an abbreviated version!
For detailed information about NAD(P)+ transhydrogenase (Re/Si-specific), go to the full flat file.

Word Map on EC 1.6.1.2

Reaction

NADPH
+
NAD+
=
NADP+
+
NADH

Synonyms

dII, dIII, energy-linked transhydrogenase, energy-linked, mitochondrial transhydrogenase, H+-thase, mitochondrial transhydrogenase, NAD transhydrogenase, NAD(P) transhydrogenase, NADH transhydrogenase, NADH-NADP-transhydrogenase, NADPH transhydrogenase, NADPH-NAD oxidoreductase, NADPH-NAD transhydrogenase, NADPH:NAD+ transhydrogenase, nicotinamide adenine dinucleotide (phosphate) transhydrogenase, nicotinamide nucleotide transhydrogenase, NNT, PNT, PntAB, proton-translocating nicotinamide nucleotide transhydrogenase, proton-translocating transhydrogenase, pyridine nucleotide transferase, pyridine nucleotide transhydrogenase, reversible mitochondrial membrane-associated transhydrogenase, transhydrogenase, transhydrogenase, nicotinamide adenine dinucleotide (phosphate)

ECTree

     1 Oxidoreductases
         1.6 Acting on NADH or NADPH
             1.6.1 With NAD+ or NADP+ as acceptor
                1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)

Engineering

Engineering on EC 1.6.1.2 - NAD(P)+ transhydrogenase (Re/Si-specific)

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A1008P
the mutation is associated with familial glucocorticoid deficiency
A533V
the mutation is associated with familial glucocorticoid deficiency
A553V
the mutation is associated with familial glucocorticoid deficiency
D277Y
the mutation is associated with left ventricular noncompaction
F215S
G200S
G664R
the mutation is associated with familial glucocorticoid deficiency
G678A
the mutation is associated with familial glucocorticoid deficiency
G678R
the mutation is associated with familial glucocorticoid deficiency
G862D
the mutation is associated with familial glucocorticoid deficiency
H365P
the mutation is associated with familial glucocorticoid deficiency
L977P
the mutation is associated with familial glucocorticoid deficiency
N1009K
the mutation is associated with familial glucocorticoid deficiency
P437L
the mutation is associated with familial glucocorticoid deficiency
S193N
T357A
the mutation is associated with familial glucocorticoid deficiency
Y201K
the mutation is associated with familial glucocorticoid deficiency
Y388S
the mutation is associated with familial glucocorticoid deficiency
E155W
-
dIII domain, displays similar catalytic properties as wild type, introduced tryptophan fluorescence is sensitive to the redox state of the bound nucleotide
Y235F
Y235N
additional information